These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 29770599)

  • 1. Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains.
    Dalle Vedove A; Spiliotopoulos D; D'Agostino VG; Marchand JR; Unzue A; Nevado C; Lolli G; Caflisch A
    ChemMedChem; 2018 Jul; 13(14):1479-1487. PubMed ID: 29770599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
    Chen P; Chaikuad A; Bamborough P; Bantscheff M; Bountra C; Chung CW; Fedorov O; Grandi P; Jung D; Lesniak R; Lindon M; Müller S; Philpott M; Prinjha R; Rogers C; Selenski C; Tallant C; Werner T; Willson TM; Knapp S; Drewry DH
    J Med Chem; 2016 Feb; 59(4):1410-24. PubMed ID: 25799074
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of BAZ2A bromodomain ligands.
    Spiliotopoulos D; Wamhoff EC; Lolli G; Rademacher C; Caflisch A
    Eur J Med Chem; 2017 Oct; 139():564-572. PubMed ID: 28837921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reevaluation of bromodomain ligands targeting BAZ2A.
    Cazzanelli G; Vedove AD; Parolin E; D'Agostino VG; Unzue A; Nevado C; Caflisch A; Lolli G
    Protein Sci; 2023 Sep; 32(9):e4752. PubMed ID: 37574751
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography.
    Lolli G; Caflisch A
    ACS Chem Biol; 2016 Mar; 11(3):800-7. PubMed ID: 26942307
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The "Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains.
    Unzue A; Zhao H; Lolli G; Dong J; Zhu J; Zechner M; Dolbois A; Caflisch A; Nevado C
    J Med Chem; 2016 Apr; 59(7):3087-97. PubMed ID: 26982797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking.
    Marchand JR; Dalle Vedove A; Lolli G; Caflisch A
    J Chem Inf Model; 2017 Oct; 57(10):2584-2597. PubMed ID: 28862840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a BAZ2A Bromodomain Hit Compound by Fragment Joining.
    Dalle Vedove A; Cazzanelli G; Corsi J; Sedykh M; D'Agostino VG; Caflisch A; Lolli G
    ACS Bio Med Chem Au; 2021 Dec; 1(1):5-10. PubMed ID: 36147311
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B.
    Drouin L; McGrath S; Vidler LR; Chaikuad A; Monteiro O; Tallant C; Philpott M; Rogers C; Fedorov O; Liu M; Akhtar W; Hayes A; Raynaud F; Müller S; Knapp S; Hoelder S
    J Med Chem; 2015 Mar; 58(5):2553-9. PubMed ID: 25719566
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding Selectivity of Inhibitors toward Bromodomains BAZ2A and BAZ2B Uncovered by Multiple Short Molecular Dynamics Simulations and MM-GBSA Calculations.
    Wang L; Wang Y; Yang Z; Xu S; Li H
    ACS Omega; 2021 May; 6(18):12036-12049. PubMed ID: 34056358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors.
    Romero FA; Taylor AM; Crawford TD; Tsui V; Côté A; Magnuson S
    J Med Chem; 2016 Feb; 59(4):1271-98. PubMed ID: 26572217
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small molecule inhibitors of bromodomain-acetyl-lysine interactions.
    Brand M; Measures AR; Wilson BG; Cortopassi WA; Alexander R; Höss M; Hewings DS; Rooney TP; Paton RS; Conway SJ
    ACS Chem Biol; 2015 Jan; 10(1):22-39. PubMed ID: 25549280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent and selective bivalent inhibitors of BET bromodomains.
    Waring MJ; Chen H; Rabow AA; Walker G; Bobby R; Boiko S; Bradbury RH; Callis R; Clark E; Dale I; Daniels DL; Dulak A; Flavell L; Holdgate G; Jowitt TA; Kikhney A; McAlister M; Méndez J; Ogg D; Patel J; Petteruti P; Robb GR; Robers MB; Saif S; Stratton N; Svergun DI; Wang W; Whittaker D; Wilson DM; Yao Y
    Nat Chem Biol; 2016 Dec; 12(12):1097-1104. PubMed ID: 27775716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing.
    Dalle Vedove A; Cazzanelli G; Batiste L; Marchand JR; Spiliotopoulos D; Corsi J; D'Agostino VG; Caflisch A; Lolli G
    ACS Med Chem Lett; 2022 Sep; 13(9):1434-1443. PubMed ID: 36105334
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico fragment-based drug design with SEED.
    Marchand JR; Caflisch A
    Eur J Med Chem; 2018 Aug; 156():907-917. PubMed ID: 30064119
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of selective inhibitors for cyclic AMP response element-binding protein: a combined ligand and structure-based resources pipeline.
    Muneer I; Ul Qamar MT; Tusleem K; Abdul Rauf S; Hussain HMJ; Siddiqi AR
    Anticancer Drugs; 2019 Apr; 30(4):363-373. PubMed ID: 30499778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
    Karim RM; Chan A; Zhu JY; Schönbrunn E
    J Med Chem; 2020 Mar; 63(6):3227-3237. PubMed ID: 32091206
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
    Theodoulou NH; Bamborough P; Bannister AJ; Becher I; Bit RA; Che KH; Chung CW; Dittmann A; Drewes G; Drewry DH; Gordon L; Grandi P; Leveridge M; Lindon M; Michon AM; Molnar J; Robson SC; Tomkinson NC; Kouzarides T; Prinjha RK; Humphreys PG
    J Med Chem; 2016 Feb; 59(4):1425-39. PubMed ID: 25856009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective recognition of acetylated histones by bromodomains in transcriptional co-activators.
    Hassan AH; Awad S; Al-Natour Z; Othman S; Mustafa F; Rizvi TA
    Biochem J; 2007 Feb; 402(1):125-33. PubMed ID: 17049045
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach.
    Miller DC; Martin MP; Adhikari S; Brennan A; Endicott JA; Golding BT; Hardcastle IR; Heptinstall A; Hobson S; Jennings C; Molyneux L; Ng Y; Wedge SR; Noble MEM; Cano C
    Org Biomol Chem; 2018 Mar; 16(11):1843-1850. PubMed ID: 29469144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.