BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 29771176)

  • 1. Potential use of CXCL12/CXCR4 and sonic hedgehog pathways as therapeutic targets in medulloblastoma.
    Amarante MK; Vitiello GAF; Rosa MH; Mancilla IA; Watanabe MAE
    Acta Oncol; 2018 Sep; 57(9):1134-1142. PubMed ID: 29771176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration.
    Yuan L; Zhang H; Liu J; Rubin JB; Cho YJ; Shu HK; Schniederjan M; MacDonald TJ
    Mol Cancer; 2013 Mar; 12():18. PubMed ID: 23497290
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted treatment for sonic hedgehog-dependent medulloblastoma.
    Kieran MW
    Neuro Oncol; 2014 Aug; 16(8):1037-47. PubMed ID: 24951114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reprogramming Medulloblastoma-Propagating Cells by a Combined Antagonism of Sonic Hedgehog and CXCR4.
    Ward SA; Warrington NM; Taylor S; Kfoury N; Luo J; Rubin JB
    Cancer Res; 2017 Mar; 77(6):1416-1426. PubMed ID: 28031228
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of CXCL12 and CXCR4 in normal cerebellar development and medulloblastoma.
    Ozawa PM; Ariza CB; Ishibashi CM; Fujita TC; Banin-Hirata BK; Oda JM; Watanabe MA
    Int J Cancer; 2016 Jan; 138(1):10-3. PubMed ID: 25400097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma.
    Sengupta R; Dubuc A; Ward S; Yang L; Northcott P; Woerner BM; Kroll K; Luo J; Taylor MD; Wechsler-Reya RJ; Rubin JB
    Cancer Res; 2012 Jan; 72(1):122-32. PubMed ID: 22052462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
    Milla LA; Arros A; Espinoza N; Remke M; Kool M; Taylor MD; Pfister SM; Wainwright BJ; Palma V
    Int J Cancer; 2014 Jan; 134(1):21-31. PubMed ID: 23775842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma.
    Lospinoso Severini L; Ghirga F; Bufalieri F; Quaglio D; Infante P; Di Marcotullio L
    Expert Opin Ther Targets; 2020 Nov; 24(11):1159-1181. PubMed ID: 32990091
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells.
    Elamin MH; Shinwari Z; Hendrayani SF; Al-Hindi H; Al-Shail E; Khafaga Y; Al-Kofide A; Aboussekhra A
    Mol Carcinog; 2010 Mar; 49(3):302-14. PubMed ID: 20025076
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
    Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
    Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks.
    Po A; Abballe L; Sabato C; Gianno F; Chiacchiarini M; Catanzaro G; De Smaele E; Giangaspero F; Ferretti E; Miele E; Besharat ZM
    Int J Mol Sci; 2018 Aug; 19(8):. PubMed ID: 30096798
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
    Singh AR; Joshi S; Zulcic M; Alcaraz M; Garlich JR; Morales GA; Cho YJ; Bao L; Levy ML; Newbury R; Malicki D; Messer K; Crawford J; Durden DL
    PLoS One; 2016; 11(3):e0150836. PubMed ID: 26938241
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis.
    Lin Z; Li S; Sheng H; Cai M; Ma LY; Hu L; Xu S; Yu LS; Zhang N
    J Cancer Res Clin Oncol; 2016 Dec; 142(12):2469-2478. PubMed ID: 27601167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New Approaches in Targeted Therapy for Medulloblastoma in Children.
    Maier H; Dalianis T; Kostopoulou ON
    Anticancer Res; 2021 Apr; 41(4):1715-1726. PubMed ID: 33813375
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.
    Pambid MR; Berns R; Adomat HH; Hu K; Triscott J; Maurer N; Zisman N; Ramaswamy V; Hawkins CE; Taylor MD; Dunham C; Guns E; Dunn SE
    Pediatr Blood Cancer; 2014 Jan; 61(1):107-15. PubMed ID: 23940083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model.
    Tan IL; Arifa RDN; Rallapalli H; Kana V; Lao Z; Sanghrajka RM; Sumru Bayin N; Tanne A; Wojcinski A; Korshunov A; Bhardwaj N; Merad M; Turnbull DH; Lafaille JJ; Joyner AL
    Oncogene; 2021 Jan; 40(2):396-407. PubMed ID: 33159168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Engineered biomimetic nanoparticle for dual targeting of the cancer stem-like cell population in sonic hedgehog medulloblastoma.
    Kim J; Dey A; Malhotra A; Liu J; Ahn SI; Sei YJ; Kenney AM; MacDonald TJ; Kim Y
    Proc Natl Acad Sci U S A; 2020 Sep; 117(39):24205-24212. PubMed ID: 32934143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Restore the brake on tumor progression.
    Gordon RE; Zhang L; Yang ZJ
    Biochem Pharmacol; 2017 Aug; 138():1-6. PubMed ID: 28389227
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.
    Dang MT; Gonzalez MV; Gaonkar KS; Rathi KS; Young P; Arif S; Zhai L; Alam Z; Devalaraja S; To TKJ; Folkert IW; Raman P; Rokita JL; Martinez D; Taroni JN; Shapiro JA; Greene CS; Savonen C; Mafra F; Hakonarson H; Curran T; Haldar M
    Cell Rep; 2021 Mar; 34(13):108917. PubMed ID: 33789113
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nkx2-2as Suppression Contributes to the Pathogenesis of Sonic Hedgehog Medulloblastoma.
    Zhang Y; Wang T; Wang S; Xiong Y; Zhang R; Zhang X; Zhao J; Yang AG; Wang L; Jia L
    Cancer Res; 2018 Feb; 78(4):962-973. PubMed ID: 29229597
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.