BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

59 related articles for article (PubMed ID: 29773504)

  • 1. Discovery of novel 20S proteasome inhibitors by rational topology-based scaffold hopping of bortezomib.
    Xu Y; Yang X; Chen Y; Chen H; Sun H; Li W; Xie Q; Yu L; Shao L
    Bioorg Med Chem Lett; 2018 Jul; 28(12):2148-2152. PubMed ID: 29773504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bortezomib Inhibits Open Configurations of the 20S Proteasome.
    Henderson LW; Gautam AKS; Sharon EM; Johnson CR; Rommel NG; Anthony AJ; Russell DH; Jarrold MF; Matouschek A; Clemmer DE
    J Am Soc Mass Spectrom; 2024 Jun; 35(6):1063-1068. PubMed ID: 38748611
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substituted quinolines as noncovalent proteasome inhibitors.
    McDaniel TJ; Lansdell TA; Dissanayake AA; Azevedo LM; Claes J; Odom AL; Tepe JJ
    Bioorg Med Chem; 2016 Jun; 24(11):2441-2450. PubMed ID: 27112450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies.
    Lei M; Feng H; Wang C; Li H; Shi J; Wang J; Liu Z; Chen S; Hu S; Zhu Y
    Bioorg Med Chem; 2016 Jun; 24(11):2576-2588. PubMed ID: 27117691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols.
    Glynn SJ; Gaffney KJ; Sainz MA; Louie SG; Petasis NA
    Org Biomol Chem; 2015 Apr; 13(13):3887-99. PubMed ID: 25669488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment.
    Wang H; Wu Z; Cao Y; Gao L; Shao J; Zhao Y; Zhang J; Zhou Y; Wei G; Li J; Zhu H
    Bioorg Chem; 2023 Sep; 138():106626. PubMed ID: 37295239
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immunoproteasome β5i-Selective Dipeptidomimetic Inhibitors.
    Singh PK; Fan H; Jiang X; Shi L; Nathan CF; Lin G
    ChemMedChem; 2016 Oct; 11(19):2127-2131. PubMed ID: 27561172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of proteasome subunit selectivity of syringolins.
    Tatsumi K; Kitahata S; Komatani Y; Katsuyama A; Yakushiji F; Ichikawa S
    Bioorg Med Chem; 2024 May; 106():117733. PubMed ID: 38704960
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rational design of proteasome inhibitors based on the structure of the endogenous inhibitor PI31/Fub1.
    Velez B; Razi A; Hubbard RD; Walsh R; Rawson S; Tian G; Finley D; Hanna J
    Proc Natl Acad Sci U S A; 2023 Dec; 120(51):e2308417120. PubMed ID: 38091293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Highly Selective Inhibitors of the Human Constitutive Proteasome β5c Chymotryptic Subunit.
    Zhan W; Li D; Saha P; Wang R; Zhang H; Ajay AK; Deban C; Sukenick G; Azzi J; Lin G
    J Med Chem; 2023 Jan; 66(2):1172-1185. PubMed ID: 36608337
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The proteasome controls ESCRT-III-mediated cell division in an archaeon.
    Tarrason Risa G; Hurtig F; Bray S; Hafner AE; Harker-Kirschneck L; Faull P; Davis C; Papatziamou D; Mutavchiev DR; Fan C; Meneguello L; Arashiro Pulschen A; Dey G; Culley S; Kilkenny M; Souza DP; Pellegrini L; de Bruin RAM; Henriques R; Snijders AP; Šarić A; Lindås AC; Robinson NP; Baum B
    Science; 2020 Aug; 369(6504):. PubMed ID: 32764038
    [No Abstract]   [Full Text] [Related]  

  • 12. Discovery of an Inhibitor of the Proteasome Subunit Rpn11.
    Perez C; Li J; Parlati F; Rouffet M; Ma Y; Mackinnon AL; Chou TF; Deshaies RJ; Cohen SM
    J Med Chem; 2017 Feb; 60(4):1343-1361. PubMed ID: 28191850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-Activity Relationship Studies of Antimalarial
    Zhang H; Ginn J; Zhan W; Leung A; Liu YJ; Toita A; Okamoto R; Wong TT; Imaeda T; Hara R; Michino M; Yukawa T; Chelebieva S; Tumwebaze PK; Vendome J; Beuming T; Sato K; Aso K; Rosenthal PJ; Cooper RA; Liverton N; Foley M; Meinke PT; Nathan CF; Kirkman LA; Lin G
    J Med Chem; 2023 Jan; 66(2):1484-1508. PubMed ID: 36630286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macrocyclic Peptides that Selectively Inhibit the
    Zhang H; Hsu HC; Kahne SC; Hara R; Zhan W; Jiang X; Burns-Huang K; Ouellette T; Imaeda T; Okamoto R; Kawasaki M; Michino M; Wong TT; Toita A; Yukawa T; Moraca F; Vendome J; Saha P; Sato K; Aso K; Ginn J; Meinke PT; Foley M; Nathan CF; Darwin KH; Li H; Lin G
    J Med Chem; 2021 May; 64(9):6262-6272. PubMed ID: 33949190
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome - insights into the enzyme activation mechanism.
    Witkowska J; Giżyńska M; Grudnik P; Golik P; Karpowicz P; Giełdoń A; Dubin G; Jankowska E
    Sci Rep; 2017 Jul; 7(1):6177. PubMed ID: 28733623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth.
    de Souza RTMP; Freire VF; Gubiani JR; Ferreira RO; Trivella DBB; Moraes FC; Paradas WC; Salgado LT; Pereira RC; Amado Filho GM; Ferreira AG; Williams DE; Andersen RJ; Molinski TF; Berlinck RGS
    J Nat Prod; 2018 Oct; 81(10):2296-2300. PubMed ID: 30281303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elemene sensitizes pancreatic cancer cells to bortezomib by enhancing proteasome inhibition via molecular patch mechanism.
    Hou S; Li Z; Chen X; Wang W; Duan T; Scampavia L; Yuan Y; Spicer TP; Chen X; Xie T
    Signal Transduct Target Ther; 2023 Feb; 8(1):87. PubMed ID: 36849489
    [No Abstract]   [Full Text] [Related]  

  • 18. Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation.
    Sun S; Fushimi M; Rossetti T; Kaur N; Ferreira J; Miller M; Quast J; van den Heuvel J; Steegborn C; Levin LR; Buck J; Myers RW; Kargman S; Liverton N; Meinke PT; Huggins DJ
    J Chem Inf Model; 2023 May; 63(9):2828-2841. PubMed ID: 37060320
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Addition to "Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation".
    Sun S; Fushimi M; Rossetti T; Kaur N; Ferreira J; Miller M; Quast J; van den Heuvel J; Steegborn C; Levin LR; Buck J; Myers RW; Kargman S; Liverton N; Meinke PT; Huggins DJ
    J Chem Inf Model; 2024 Feb; 64(3):1106. PubMed ID: 38258980
    [No Abstract]   [Full Text] [Related]  

  • 20. Theoretical Evaluation of Novel Thermolysin Inhibitors from
    Lamazares E; MacLeod-Carey D; Miranda FP; Mena-Ulecia K
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33451037
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.