143 related articles for article (PubMed ID: 2977647)
1. Inhibition of intestinal pyrimidine nucleoside phosphorylases.
Wientjes MG; Au JL
Pharm Res; 1987 Oct; 4(5):425-8. PubMed ID: 2977647
[TBL] [Abstract][Full Text] [Related]
2. Effect of uridine coadministration on 5'-deoxy-5-fluorouridine disposition in rats.
Au JL; Wientjes MG; Bramer SL
Cancer Chemother Pharmacol; 1988; 22(1):5-10. PubMed ID: 2969304
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of 5'-deoxy-5-fluorouridine phosphorolysis by acyclopyrimidinenucleosides in intestinal tissue homogenates.
Hamada A; Fukushima S; Saneyoshi M; Kawaguchi T; Nakano M
Biol Pharm Bull; 1995 Jan; 18(1):172-5. PubMed ID: 7735236
[TBL] [Abstract][Full Text] [Related]
4. Modulation of the pharmacokinetics of 5'-deoxy-5-fluorouridine and 5-fluorouracil in rats by oral co-administration of acyclothymidine.
Hamada A; Fukushima S; Saneyoshi M; Shimizu S; Kawaguchi T; Nakano M
Biol Pharm Bull; 1996 May; 19(5):729-32. PubMed ID: 8741584
[TBL] [Abstract][Full Text] [Related]
5. [Conversion of 5'-deoxy-5-fluorouridine to 5-FU by pyrimidine nucleoside phosphorylases in normal and tumor tissues from rodents bearing tumors and cancer patients].
Miwa M; Nishimura J; Kamiyama T; Ishitsuka H
Gan To Kagaku Ryoho; 1987 Oct; 14(10):2924-9. PubMed ID: 2959206
[TBL] [Abstract][Full Text] [Related]
6. Effect of coadministered uridine on intestinal first-pass metabolism of 5'-deoxy-5-fluorouridine in conscious rats--an evaluation by method of portal-systemic concentration difference.
Sawai Y; Yamaoka K; Nakagawa T
Pharm Res; 1998 Jul; 15(7):1007-11. PubMed ID: 9688052
[TBL] [Abstract][Full Text] [Related]
7. Differential effects of acyclothymidine, a potent pyrimidine nucleoside phosphorylase inhibitor, on the pharmacokinetics of doxifluridine in rabbits via oral administration.
Hamada A; Fukushima S; Morinaga A; Saneyoshi M; Kawaguchi T; Nakano M
Biol Pharm Bull; 1993 Dec; 16(12):1297-300. PubMed ID: 8130783
[TBL] [Abstract][Full Text] [Related]
8. Antitumor activity of 5'-deoxy-5-fluorouridine in human digestive organ cancer xenografts and pyrimidine nucleoside phosphorylase activity in normal and neoplastic tissues from human digestive organs.
Nio Y; Kimura H; Tsubono M; Tseng CC; Kawabata K; Masai Y; Hayashi H; Meyer C; Fukumoto M; Tobe T
Anticancer Res; 1992; 12(4):1141-6. PubMed ID: 1386969
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of 5'-deoxy-5-fluorouridine phosphorolysis by acyclothymidine in tumor cell homogenates.
Hamada A; Nakano M; Shimidzu S; Hasegawa T; Kawaguchi T
Biol Pharm Bull; 1997 Aug; 20(8):935-8. PubMed ID: 9300147
[TBL] [Abstract][Full Text] [Related]
10. [5'-Deoxy-5-fluorouridine enzymatic activation from the masked compound to 5-fluorouracil in human malignant tissues].
Hara Y
Gan To Kagaku Ryoho; 1984 Oct; 11(10):2133-43. PubMed ID: 6237613
[TBL] [Abstract][Full Text] [Related]
11. Differential selectivity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in cultured human B lymphocytes and mouse L1210 leukemia.
Au JL; Rustum YM; Minowada J; Srivastava BI
Biochem Pharmacol; 1983 Feb; 32(3):541-6. PubMed ID: 6221728
[TBL] [Abstract][Full Text] [Related]
12. Comparative antitumor activity and intestinal toxicity of 5'-deoxy-5-fluorouridine and its prodrug trimethoxybenzoyl-5'-deoxy-5-fluorocytidine.
Ninomiya Y; Miwa M; Eda H; Sahara H; Fujimoto K; Ishida M; Umeda I; Yokose K; Ishitsuka H
Jpn J Cancer Res; 1990 Feb; 81(2):188-95. PubMed ID: 2139643
[TBL] [Abstract][Full Text] [Related]
13. [The study of 5-FU levels and pyrimidine nucleoside phosphorylase (PyNPase) activity in human breast cancer tissue after administration of 5'-deoxy-5-fluorouridine (5'-DFUR)].
Yayoi E; Takatsuka Y; Miyauchi K; Hirai T; Aikawa T; Maeura Y; Kaji M; Kitada M; Kotsuma Y; Satomi T
Gan To Kagaku Ryoho; 1990 Jul; 17(7):1371-4. PubMed ID: 2142401
[No Abstract] [Full Text] [Related]
14. Role of uridine phosphorylase for antitumor activity of 5'-deoxy-5-fluorouridine.
Ishitsuka H; Miwa M; Takemoto K; Fukuoka K; Itoga A; Maruyama HB
Gan; 1980 Feb; 71(1):112-23. PubMed ID: 6445847
[TBL] [Abstract][Full Text] [Related]
15. [Investigation of 5-fluorouracil (5-FU) levels and pyrimidine nucleoside phosphorylase activities in the tissues from patients with uterine cervical and ovarian cancers after oral administration of 5'-DFUR].
Noda K; Watanabe Y; Ikeda M; Takeuchi K; Hasegawa K; Kinugasa M; Sekiba K; Kobashi Y; Ohiwa T; Odagiri H
Gan To Kagaku Ryoho; 1991 Dec; 18(15):2551-5. PubMed ID: 1836128
[TBL] [Abstract][Full Text] [Related]
16. Effects of orally administered 5-fluorouracil and its derivative 5'-deoxy-5-fluorouridine on 7,12-dimethylbenz[a]anthracene-induced breast carcinomas in rats.
Sawada Y; Ohno T; Shimoyama T; Uematsu K; Odagiri H
J Int Med Res; 1991; 19(3):249-70. PubMed ID: 1834492
[TBL] [Abstract][Full Text] [Related]
17. Tumor specific conversion of a pyrimidine antimetabolite.
Hartmann HR; Bollag W
Adv Exp Med Biol; 1984; 165 Pt B():411-4. PubMed ID: 6232832
[TBL] [Abstract][Full Text] [Related]
18. Differences in activities and substrate specificity of human and murine pyrimidine nucleoside phosphorylases: implications for chemotherapy with 5-fluoropyrimidines.
el Kouni MH; el Kouni MM; Naguib FN
Cancer Res; 1993 Aug; 53(16):3687-93. PubMed ID: 8339277
[TBL] [Abstract][Full Text] [Related]
19. Moment analysis of intestinal first-pass metabolism by portal-systemic concentration difference in single conscious rat using 5'-deoxy-5-fluorouridine and 5-fluorouracil as model drug system.
Sawai Y; Yamaoka K; Takemura A; Nakagawa T
J Pharm Sci; 1997 Nov; 86(11):1269-72. PubMed ID: 9383738
[TBL] [Abstract][Full Text] [Related]
20. [Correlation between pyrimidine nucleoside phosphorylase (PyNPase)/thymidine phosphorylase/platelet-derived endothelial cell growth factor and histological prognostic factor, and influence of 5'-deoxy-5-fluorouridine (5'-DFUR) administration on PyNPase activities and serum immunosuppressive acidic protein levels. A study group of oral anti-cancer drugs in Seiban/Tajima area].
Satoh B; Ohtoshi M; Ishida Y; Hen-mi K; Kaneko I; Soda M; Sugihara J; Shibagaki F; Iwai N; Nakamura T; Yamasaki T; Matsumoto S
Gan To Kagaku Ryoho; 1998 Feb; 25(3):359-64. PubMed ID: 9492829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
