BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 29780379)

  • 1. Point Mutation of a Non-Elastase-Binding Site in Human α1-Antitrypsin Alters Its Anti-Inflammatory Properties.
    Lior Y; Zaretsky M; Ochayon DE; Lotysh D; Baranovski BM; Schuster R; Guttman O; Aharoni A; Lewis EC
    Front Immunol; 2018; 9():759. PubMed ID: 29780379
    [TBL] [Abstract][Full Text] [Related]  

  • 2. S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination.
    Kaner Z; Engelman R; Schuster R; Rider P; Greenberg D; Av-Gay Y; Benhar M; Lewis EC
    Front Immunol; 2019; 10():590. PubMed ID: 31001247
    [No Abstract]   [Full Text] [Related]  

  • 3. Single amino acid substitutions in recombinant plant-derived human α1-proteinase inhibitor confer enhanced stability and functional efficacy.
    Jha S; Sanyal I; Amla DV
    Biochim Biophys Acta; 2014 Jan; 1840(1):416-27. PubMed ID: 24090883
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase.
    Jonigk D; Al-Omari M; Maegel L; Müller M; Izykowski N; Hong J; Hong K; Kim SH; Dorsch M; Mahadeva R; Laenger F; Kreipe H; Braun A; Shahaf G; Lewis EC; Welte T; Dinarello CA; Janciauskiene S
    Proc Natl Acad Sci U S A; 2013 Sep; 110(37):15007-12. PubMed ID: 23975926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human α1-antitrypsin modifies B-lymphocyte responses during allograft transplantation.
    Mizrahi M; Cal P; Rosenthal M; Ochayon D; Shahaf G; Kaner Z; Kachker P; Lewis EC
    Immunology; 2013 Nov; 140(3):362-73. PubMed ID: 23829472
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Curcumin inhibits tumor proliferation induced by neutrophil elastase through the upregulation of α1-antitrypsin in lung cancer.
    Xu Y; Zhang J; Han J; Pan X; Cao Y; Guo H; Pan Y; An Y; Li X
    Mol Oncol; 2012 Aug; 6(4):405-17. PubMed ID: 22507634
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of directed evolution and back-to-consensus algorithms to human alpha1-antitrypsin leads to diminished anti-protease activity and augmented anti-inflammatory activities.
    Lior Y; Jasevitch M; Ochayon DE; Zaretsky M; Lewis EC; Aharoni A
    Cell Immunol; 2020 Sep; 355():104135. PubMed ID: 32703529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector.
    Lu Y; Choi YK; Campbell-Thompson M; Li C; Tang Q; Crawford JM; Flotte TR; Song S
    J Gene Med; 2006 Jun; 8(6):730-5. PubMed ID: 16518879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection.
    Shahaf G; Moser H; Ozeri E; Mizrahi M; Abecassis A; Lewis EC
    Mol Med; 2011; 17(9-10):1000-11. PubMed ID: 21670848
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Accelerated Wound Border Closure Using a Microemulsion Containing Non-Inhibitory Recombinant α1-Antitrypsin.
    Gimmon A; Sherker L; Kojukarov L; Zaknoun M; Lior Y; Fadel T; Schuster R; Lewis EC; Silberstein E
    Int J Mol Sci; 2022 Jul; 23(13):. PubMed ID: 35806370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation.
    Abecassis A; Schuster R; Shahaf G; Ozeri E; Green R; Ochayon DE; Rider P; Lewis EC
    Cell Mol Immunol; 2014 Jul; 11(4):377-86. PubMed ID: 25000533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acute phase protein α1-antitrypsin reduces the bacterial burden in mice by selective modulation of innate cell responses.
    Kaner Z; Ochayon DE; Shahaf G; Baranovski BM; Bahar N; Mizrahi M; Lewis EC
    J Infect Dis; 2015 May; 211(9):1489-98. PubMed ID: 25389308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Implication of interfering antibody formation and apoptosis as two different mechanisms leading to variable duration of adenovirus-mediated transgene expression in immune-competent mice.
    Schowalter DB; Himeda CL; Winther BL; Wilson CB; Kay MA
    J Virol; 1999 Jun; 73(6):4755-66. PubMed ID: 10233936
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.
    Filion ML; Bhakta V; Nguyen LH; Liaw PS; Sheffield WP
    Biochemistry; 2004 Nov; 43(46):14864-72. PubMed ID: 15544357
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The design of a new truncated and engineered alpha1-antitrypsin based on theoretical studies: an antiprotease therapeutics for pulmonary diseases.
    Pirooznia N; Hasannia S; Arab SS; Lotfi AS; Ghanei M; Shali A
    Theor Biol Med Model; 2013 May; 10():36. PubMed ID: 23705923
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Local regulation of neutrophil elastase activity by endogenous α1-antitrypsin in lipopolysaccharide-primed hematological cells.
    Dokai M; Madoiwa S; Yasumoto A; Kashiwakura Y; Ishiwata A; Sakata A; Makino N; Ohmori T; Mimuro J; Sakata Y
    Thromb Res; 2011 Sep; 128(3):283-92. PubMed ID: 21624645
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monoclonal antibodies to the reactive centre loop (RCL) of human corticosteroid-binding globulin (CBG) can protect against proteolytic cleavage.
    Lewis JG; Elder PA
    J Steroid Biochem Mol Biol; 2017 Jul; 171():247-253. PubMed ID: 28411181
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity.
    Ordóñez A; Pérez J; Tan L; Dickens JA; Motamedi-Shad N; Irving JA; Haq I; Ekeowa U; Marciniak SJ; Miranda E; Lomas DA
    FASEB J; 2015 Jun; 29(6):2667-78. PubMed ID: 25757566
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Asn347 Glycosylation of Corticosteroid-binding Globulin Fine-tunes the Host Immune Response by Modulating Proteolysis by Pseudomonas aeruginosa and Neutrophil Elastase.
    Sumer-Bayraktar Z; Grant OC; Venkatakrishnan V; Woods RJ; Packer NH; Thaysen-Andersen M
    J Biol Chem; 2016 Aug; 291(34):17727-42. PubMed ID: 27339896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
    Ryu SE; Choi HJ; Kwon KS; Lee KN; Yu MH
    Structure; 1996 Oct; 4(10):1181-92. PubMed ID: 8939743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.