1848 related articles for article (PubMed ID: 29784049)
1. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
Rangaraju S; Dammer EB; Raza SA; Rathakrishnan P; Xiao H; Gao T; Duong DM; Pennington MW; Lah JJ; Seyfried NT; Levey AI
Mol Neurodegener; 2018 May; 13(1):24. PubMed ID: 29784049
[TBL] [Abstract][Full Text] [Related]
2. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.
Rangaraju S; Dammer EB; Raza SA; Gao T; Xiao H; Betarbet R; Duong DM; Webster JA; Hales CM; Lah JJ; Levey AI; Seyfried NT
Mol Neurodegener; 2018 Jun; 13(1):34. PubMed ID: 29954413
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα.
Gao T; Jernigan J; Raza SA; Dammer EB; Xiao H; Seyfried NT; Levey AI; Rangaraju S
Glia; 2019 Oct; 67(10):1958-1975. PubMed ID: 31301160
[TBL] [Abstract][Full Text] [Related]
4. Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease.
Ramesha S; Rayaprolu S; Bowen CA; Giver CR; Bitarafan S; Nguyen HM; Gao T; Chen MJ; Nwabueze N; Dammer EB; Engstrom AK; Xiao H; Pennati A; Seyfried NT; Katz DJ; Galipeau J; Wulff H; Waller EK; Wood LB; Levey AI; Rangaraju S
Proc Natl Acad Sci U S A; 2021 Mar; 118(11):. PubMed ID: 33649184
[TBL] [Abstract][Full Text] [Related]
5. Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept.
Maezawa I; Nguyen HM; Di Lucente J; Jenkins DP; Singh V; Hilt S; Kim K; Rangaraju S; Levey AI; Wulff H; Jin LW
Brain; 2018 Feb; 141(2):596-612. PubMed ID: 29272333
[TBL] [Abstract][Full Text] [Related]
6. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation.
Rangaraju S; Raza SA; Pennati A; Deng Q; Dammer EB; Duong D; Pennington MW; Tansey MG; Lah JJ; Betarbet R; Seyfried NT; Levey AI
J Neuroinflammation; 2017 Jun; 14(1):128. PubMed ID: 28651603
[TBL] [Abstract][Full Text] [Related]
7. Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease.
Sobue A; Komine O; Hara Y; Endo F; Mizoguchi H; Watanabe S; Murayama S; Saito T; Saido TC; Sahara N; Higuchi M; Ogi T; Yamanaka K
Acta Neuropathol Commun; 2021 Jan; 9(1):1. PubMed ID: 33402227
[TBL] [Abstract][Full Text] [Related]
8. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease.
Rayaprolu S; Gao T; Xiao H; Ramesha S; Weinstock LD; Shah J; Duong DM; Dammer EB; Webster JA; Lah JJ; Wood LB; Betarbet R; Levey AI; Seyfried NT; Rangaraju S
Mol Neurodegener; 2020 May; 15(1):28. PubMed ID: 32381088
[TBL] [Abstract][Full Text] [Related]
9. RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.
Ofengeim D; Mazzitelli S; Ito Y; DeWitt JP; Mifflin L; Zou C; Das S; Adiconis X; Chen H; Zhu H; Kelliher MA; Levin JZ; Yuan J
Proc Natl Acad Sci U S A; 2017 Oct; 114(41):E8788-E8797. PubMed ID: 28904096
[TBL] [Abstract][Full Text] [Related]
10. Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.
Ma C; Hunt JB; Kovalenko A; Liang H; Selenica MB; Orr MB; Zhang B; Gensel JC; Feola DJ; Gordon MN; Morgan D; Bickford PC; Lee DC
Front Immunol; 2021; 12():628156. PubMed ID: 34046031
[TBL] [Abstract][Full Text] [Related]
11. Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease.
Cai Z; Hussain MD; Yan LJ
Int J Neurosci; 2014 May; 124(5):307-21. PubMed ID: 23930978
[TBL] [Abstract][Full Text] [Related]
12. Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer's disease by restoring microglial function via a PPAR-γ-dependent mechanism.
Medrano-Jiménez E; Jiménez-Ferrer Carrillo I; Pedraza-Escalona M; Ramírez-Serrano CE; Álvarez-Arellano L; Cortés-Mendoza J; Herrera-Ruiz M; Jiménez-Ferrer E; Zamilpa A; Tortoriello J; Pedraza-Alva G; Pérez-Martínez L
J Neuroinflammation; 2019 Jul; 16(1):143. PubMed ID: 31291963
[TBL] [Abstract][Full Text] [Related]
13. Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR; Pham KD; Cox JEJ; Keck AW; Ko S; Ampadu FA; Porter HL; Ansere VA; Kulpa A; Kellogg CM; Machalinski AH; Thomas MA; Wright Z; Chucair-Elliott AJ; Freeman WM
J Neuroinflammation; 2023 Aug; 20(1):188. PubMed ID: 37587511
[TBL] [Abstract][Full Text] [Related]
14. Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid β-Protein Oligomers.
Xu H; Gelyana E; Rajsombath M; Yang T; Li S; Selkoe D
J Neurosci; 2016 Aug; 36(35):9041-56. PubMed ID: 27581448
[TBL] [Abstract][Full Text] [Related]
15. Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia.
Hüttenrauch M; Ogorek I; Klafki H; Otto M; Stadelmann C; Weggen S; Wiltfang J; Wirths O
Acta Neuropathol Commun; 2018 Oct; 6(1):108. PubMed ID: 30340518
[TBL] [Abstract][Full Text] [Related]
16. Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer's Disease.
Xu YJ; Au NPB; Ma CHE
Front Aging Neurosci; 2022; 14():896852. PubMed ID: 35693341
[TBL] [Abstract][Full Text] [Related]
17. Microglial motility in Alzheimer's disease and after Aβ42 immunotherapy: a human post-mortem study.
Franco-Bocanegra DK; George B; Lau LC; Holmes C; Nicoll JAR; Boche D
Acta Neuropathol Commun; 2019 Nov; 7(1):174. PubMed ID: 31703599
[TBL] [Abstract][Full Text] [Related]
18. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease.
Rangaraju S; Gearing M; Jin LW; Levey A
J Alzheimers Dis; 2015; 44(3):797-808. PubMed ID: 25362031
[TBL] [Abstract][Full Text] [Related]
19. DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Daily KP; Badr A; Eltobgy M; Estfanous S; Whitham O; Tan MH; Carafice C; Krause K; McNamara A; Hamilton K; Houle S; Gupta S; Gupta GA; Madhu S; Fitzgerald J; Saadey AA; Laster B; Yan P; Webb A; Zhang X; Pietrzak M; Kokiko-Cochran ON; Ghoneim HE; Amer AO
Alzheimers Res Ther; 2024 Feb; 16(1):29. PubMed ID: 38326859
[TBL] [Abstract][Full Text] [Related]
20. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Sudwarts A; Ramesha S; Gao T; Ponnusamy M; Wang S; Hansen M; Kozlova A; Bitarafan S; Kumar P; Beaulieu-Abdelahad D; Zhang X; Collier L; Szekeres C; Wood LB; Duan J; Thinakaran G; Rangaraju S
Mol Neurodegener; 2022 May; 17(1):33. PubMed ID: 35526014
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
