227 related articles for article (PubMed ID: 29788210)
1. Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung.
Ashmore JH; Luo S; Watson CJW; Lazarus P
Carcinogenesis; 2018 Jul; 39(8):1079-1088. PubMed ID: 29788210
[TBL] [Abstract][Full Text] [Related]
2. Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung.
Atalla A; Maser E
Toxicology; 1999 Nov; 139(1-2):155-66. PubMed ID: 10614696
[TBL] [Abstract][Full Text] [Related]
3. Expression and NNK reducing activities of carbonyl reductase and 11beta-hydroxysteroid dehydrogenase type 1 in human lung.
Finckh C; Atalla A; Nagel G; Stinner B; Maser E
Chem Biol Interact; 2001 Jan; 130-132(1-3):761-73. PubMed ID: 11306092
[TBL] [Abstract][Full Text] [Related]
4. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
Prokopczyk B; Trushin N; Leszczynska J; Waggoner SE; El-Bayoumy K
Carcinogenesis; 2001 Jan; 22(1):107-14. PubMed ID: 11159748
[TBL] [Abstract][Full Text] [Related]
5. Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
Breyer-Pfaff U; Martin HJ; Ernst M; Maser E
Drug Metab Dispos; 2004 Sep; 32(9):915-22. PubMed ID: 15319331
[TBL] [Abstract][Full Text] [Related]
6. The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols.
Trushin N; Leder G; El-Bayoumy K; Hoffmann D; Beger HG; Henne-Bruns D; Ramadani M; Prokopczyk B
Langenbecks Arch Surg; 2008 Jul; 393(4):571-9. PubMed ID: 18259773
[TBL] [Abstract][Full Text] [Related]
7. Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta.
Atalla A; Maser E
Chem Biol Interact; 2001 Jan; 130-132(1-3):737-48. PubMed ID: 11306090
[TBL] [Abstract][Full Text] [Related]
8. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
Collazo NR; Sultatos LG
Biochem Pharmacol; 1995 Nov; 50(11):1933-41. PubMed ID: 8615875
[TBL] [Abstract][Full Text] [Related]
9. Carbonyl reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytosolic enzymes in human liver and lung.
Maser E; Stinner B; Atalla A
Cancer Lett; 2000 Feb; 148(2):135-44. PubMed ID: 10695989
[TBL] [Abstract][Full Text] [Related]
10. 11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.
Maser E
Cancer Res; 1998 Jul; 58(14):2996-3003. PubMed ID: 9679962
[TBL] [Abstract][Full Text] [Related]
11. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
Upadhyaya P; Kenney PM; Hochalter JB; Wang M; Hecht SS
Carcinogenesis; 1999 Aug; 20(8):1577-82. PubMed ID: 10426810
[TBL] [Abstract][Full Text] [Related]
12. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Upadhyaya P; Kalscheuer S; Hochalter JB; Villalta PW; Hecht SS
Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
[TBL] [Abstract][Full Text] [Related]
13. Stereospecific Metabolism of the Tobacco-Specific Nitrosamine, NNAL.
Kozlovich S; Chen G; Lazarus P
Chem Res Toxicol; 2015 Nov; 28(11):2112-9. PubMed ID: 26452127
[TBL] [Abstract][Full Text] [Related]
14. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
Guo Z; Smith TJ; Thomas PE; Yang CS
Arch Biochem Biophys; 1992 Oct; 298(1):279-86. PubMed ID: 1524438
[TBL] [Abstract][Full Text] [Related]
15. Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol.
Atalla A; Breyer-Pfaff U; Maser E
Xenobiotica; 2000 Aug; 30(8):755-69. PubMed ID: 11037109
[TBL] [Abstract][Full Text] [Related]
16. Formation of NADP(H) analogs of tobacco-specific nitrosamines in rat liver and pancreatic microsomes.
Peterson LA; Ng DK; Stearns RA; Hecht SS
Chem Res Toxicol; 1994; 7(5):599-608. PubMed ID: 7841337
[TBL] [Abstract][Full Text] [Related]
17. Metastasis to the F344 Rat Pancreas from Lung Cancer Induced by 4-(Methylnitrosamino)- 1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)- 1-butanol, Constituents of Tobacco Products.
Kovi RC; Johnson CS; Balbo S; Hecht SS; O'Sullivan MG
Toxicol Pathol; 2018 Feb; 46(2):184-192. PubMed ID: 29390940
[TBL] [Abstract][Full Text] [Related]
18. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
Staretz ME; Murphy SE; Patten CJ; Nunes MG; Koehl W; Amin S; Koenig LA; Guengerich FP; Hecht SS
Drug Metab Dispos; 1997 Feb; 25(2):154-62. PubMed ID: 9029045
[TBL] [Abstract][Full Text] [Related]
19. Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4.
Wiener D; Doerge DR; Fang JL; Upadhyaya P; Lazarus P
Drug Metab Dispos; 2004 Jan; 32(1):72-9. PubMed ID: 14709623
[TBL] [Abstract][Full Text] [Related]
20. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
Richter E; Engl J; Friesenegger S; Tricker AR
Chem Res Toxicol; 2009 Jun; 22(6):1008-17. PubMed ID: 19408892
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
