BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

621 related articles for article (PubMed ID: 29793751)

  • 1. Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
    Batran RZ; Kassem AF; Abbas EMH; Elseginy SA; Mounier MM
    Bioorg Med Chem; 2018 Jul; 26(12):3474-3490. PubMed ID: 29793751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G; Liu W; Gong Z; Huang Y; Li Y; Peng Z
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):139-144. PubMed ID: 31724435
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S; Tokala R; Bajaj DM; Nagesh N; Bokara KK; Kiranmai G; Lakshmi UJ; Vadlamani S; Talla V; Shankaraiah N
    Bioorg Chem; 2019 Dec; 93():103317. PubMed ID: 31586714
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, molecular docking and biological evaluation of 1-phenylsulphonyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as novel potential tubulin assembling inhibitors.
    Wang YT; Cai XC; Shi TQ; Zhang YL; Wang ZC; Liu CH; Zhu HL
    Chem Biol Drug Des; 2017 Jul; 90(1):112-118. PubMed ID: 28032450
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
    Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
    Wang G; Peng Z; Li Y
    Chem Pharm Bull (Tokyo); 2019 Jul; 67(7):725-728. PubMed ID: 30982797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R
    Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M; Bayoumi AH; Elgamal K; Elmorsy A; Ihmaid S; Ahmed HEA
    Molecules; 2017 Dec; 23(1):. PubMed ID: 29280968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.
    Kumar NP; Thatikonda S; Tokala R; Kumari SS; Lakshmi UJ; Godugu C; Shankaraiah N; Kamal A
    Bioorg Med Chem; 2018 May; 26(8):1996-2008. PubMed ID: 29525336
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V; Pindiprolu SKSS; Sana S; Ramamurty DSVNM; Madasi JRK; Vadlamani S
    Anticancer Agents Med Chem; 2021; 21(8):1047-1055. PubMed ID: 32981511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
    Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Romagnoli R; Prencipe F; Oliva P; Baraldi S; Baraldi PG; Brancale A; Ferla S; Hamel E; Bortolozzi R; Viola G
    Bioorg Chem; 2018 Oct; 80():361-374. PubMed ID: 29986184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and molecular docking studies of new furochromone derivatives as p38α MAPK inhibitors targeting human breast cancer MCF-7 cells.
    Amin KM; Syam YM; Anwar MM; Ali HI; Abdel-Ghani TM; Serry AM
    Bioorg Med Chem; 2017 Apr; 25(8):2423-2436. PubMed ID: 28291685
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D; Liu Y; Yan W; Wang C; Bai P; Wang T; Tang M; Wang X; Yang Z; Ma B; Ma L; Lei L; Wang F; Xu B; Zhou Y; Yang T; Chen L
    J Med Chem; 2016 Jun; 59(12):5721-39. PubMed ID: 27213819
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of (E)-3-(3,4-dihydroxyphenyl)acrylylpiperazine derivatives as a new class of tubulin polymerization inhibitors.
    Yin Y; Qiao F; Jiang LY; Wang SF; Sha S; Wu X; Lv PC; Zhu HL
    Bioorg Med Chem; 2014 Aug; 22(15):4285-92. PubMed ID: 24916028
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N; Nekkanti S; Brahma UR; Praveen Kumar N; Deshpande N; Prasanna D; Senwar KR; Jaya Lakshmi U
    Bioorg Med Chem; 2017 Sep; 25(17):4805-4816. PubMed ID: 28774575
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and biological evaluation of novel 2,3-Di-O-Aryl/Alkyl sulfonate derivatives of l-ascorbic acid: Efficient access to novel anticancer agents via in vitro screening, tubulin polymerization inhibition, molecular docking study and ADME predictions.
    Deshmukh SR; Nalkar AS; Sarkate AP; Tiwari SV; Lokwani DK; Thopate SR
    Bioorg Chem; 2024 Jun; 147():107402. PubMed ID: 38688199
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.
    Kamal A; Kumar GB; Vishnuvardhan MV; Shaik AB; Reddy VS; Mahesh R; Sayeeda IB; Kapure JS
    Org Biomol Chem; 2015 Apr; 13(13):3963-81. PubMed ID: 25721862
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    Kamal A; Balakrishna M; Nayak VL; Shaik TB; Faazil S; Nimbarte VD
    ChemMedChem; 2014 Dec; 9(12):2766-80. PubMed ID: 25313981
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M; El Deeb MA; Elzahabi HSA; Elkaeed EB; Mehany ABM; Eissa IH
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):640-658. PubMed ID: 33588683
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.