140 related articles for article (PubMed ID: 29799749)
1. Design, Synthesis, and Evaluation of Novel p-(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex.
Peng W; Sun ZY; Zhang Q; Cheng SQ; Wang SK; Wang XN; Kuang GT; Su XX; Tan JH; Huang ZS; Ou TM
J Med Chem; 2018 Aug; 61(15):6629-6646. PubMed ID: 29799749
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation.
Sun JW; Zou J; Zheng Y; Yuan H; Xie YZ; Wang XN; Ou TM
Eur J Med Chem; 2024 May; 271():116406. PubMed ID: 38688064
[TBL] [Abstract][Full Text] [Related]
3. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
Lu YJ; Ou TM; Tan JH; Hou JQ; Shao WY; Peng D; Sun N; Wang XD; Wu WB; Bu XZ; Huang ZS; Ma DL; Wong KY; Gu LQ
J Med Chem; 2008 Oct; 51(20):6381-92. PubMed ID: 18821749
[TBL] [Abstract][Full Text] [Related]
4. New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC Transcription.
Liu HY; Chen AC; Yin QK; Li Z; Huang SM; Du G; He JH; Zan LP; Wang SK; Xu YH; Tan JH; Ou TM; Li D; Gu LQ; Huang ZS
J Med Chem; 2017 Jul; 60(13):5438-5454. PubMed ID: 28603988
[TBL] [Abstract][Full Text] [Related]
5. Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives.
Wang XD; Ou TM; Lu YJ; Li Z; Xu Z; Xi C; Tan JH; Huang SL; An LK; Li D; Gu LQ; Huang ZS
J Med Chem; 2010 Jun; 53(11):4390-8. PubMed ID: 20481493
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.
Zhou JL; Lu YJ; Ou TM; Zhou JM; Huang ZS; Zhu XF; Du CJ; Bu XZ; Ma L; Gu LQ; Li YM; Chan AS
J Med Chem; 2005 Nov; 48(23):7315-21. PubMed ID: 16279791
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase.
Guyen B; Schultes CM; Hazel P; Mann J; Neidle S
Org Biomol Chem; 2004 Apr; 2(7):981-8. PubMed ID: 15034620
[TBL] [Abstract][Full Text] [Related]
8. Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design.
Dai J; Carver M; Hurley LH; Yang D
J Am Chem Soc; 2011 Nov; 133(44):17673-80. PubMed ID: 21967482
[TBL] [Abstract][Full Text] [Related]
9. Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter.
Boddupally PV; Hahn S; Beman C; De B; Brooks TA; Gokhale V; Hurley LH
J Med Chem; 2012 Jul; 55(13):6076-86. PubMed ID: 22691117
[TBL] [Abstract][Full Text] [Related]
10. Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe.
Chen SB; Hu MH; Liu GC; Wang J; Ou TM; Gu LQ; Huang ZS; Tan JH
J Am Chem Soc; 2016 Aug; 138(33):10382-5. PubMed ID: 27508892
[TBL] [Abstract][Full Text] [Related]
11. Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
Ou TM; Lu YJ; Zhang C; Huang ZS; Wang XD; Tan JH; Chen Y; Ma DL; Wong KY; Tang JC; Chan AS; Gu LQ
J Med Chem; 2007 Apr; 50(7):1465-74. PubMed ID: 17346034
[TBL] [Abstract][Full Text] [Related]
12. Investigating the NRAS 5' UTR as a target for small molecules.
Balaratnam S; Torrey ZR; Calabrese DR; Banco MT; Yazdani K; Liang X; Fullenkamp CR; Seshadri S; Holewinski RJ; Andresson T; Ferré-D'Amaré AR; Incarnato D; Schneekloth JS
Cell Chem Biol; 2023 Jun; 30(6):643-657.e8. PubMed ID: 37257453
[TBL] [Abstract][Full Text] [Related]
13. Targeting G-quadruplex nucleic acids with heterocyclic alkaloids and their derivatives.
Xiong YX; Huang ZS; Tan JH
Eur J Med Chem; 2015 Jun; 97():538-51. PubMed ID: 25466923
[TBL] [Abstract][Full Text] [Related]
14. Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines.
Zhou JM; Zhu XF; Lu YJ; Deng R; Huang ZS; Mei YP; Wang Y; Huang WL; Liu ZC; Gu LQ; Zeng YX
Oncogene; 2006 Jan; 25(4):503-11. PubMed ID: 16170347
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, G-quadruplex stabilisation, docking studies, and effect on cancer cells of indolo[3,2-b]quinolines with one, two, or three basic side chains.
Lavrado J; Borralho PM; Ohnmacht SA; Castro RE; Rodrigues CM; Moreira R; dos Santos DJ; Neidle S; Paulo A
ChemMedChem; 2013 Oct; 8(10):1648-61. PubMed ID: 23960016
[TBL] [Abstract][Full Text] [Related]
16. An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex.
Kawauchi K; Sugimoto W; Yasui T; Murata K; Itoh K; Takagi K; Tsuruoka T; Akamatsu K; Tateishi-Karimata H; Sugimoto N; Miyoshi D
Nat Commun; 2018 Jun; 9(1):2271. PubMed ID: 29891945
[TBL] [Abstract][Full Text] [Related]
17. Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives.
Wu Y; Zan LP; Wang XD; Lu YJ; Ou TM; Lin J; Huang ZS; Gu LQ
Biochim Biophys Acta; 2014 Sep; 1840(9):2970-7. PubMed ID: 24931695
[TBL] [Abstract][Full Text] [Related]
18. Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2.
Zhang Y; Zeng D; Cao J; Wang M; Shu B; Kuang G; Ou TM; Tan JH; Gu LQ; Huang ZS; Li D
Biochim Biophys Acta Gen Subj; 2017 Dec; 1861(12):3246-3256. PubMed ID: 28943299
[TBL] [Abstract][Full Text] [Related]
19. Different cytotoxicities and cellular localizations of novel quindoline derivatives with or without boronic acid modifications in cancer cells.
Yin R; Zhang M; Hao C; Wang W; Qiu P; Wan S; Zhang L; Jiang T
Chem Commun (Camb); 2013 Oct; 49(76):8516-8. PubMed ID: 23942773
[TBL] [Abstract][Full Text] [Related]
20. Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation.
Cammas A; Dubrac A; Morel B; Lamaa A; Touriol C; Teulade-Fichou MP; Prats H; Millevoi S
RNA Biol; 2015; 12(3):320-9. PubMed ID: 25826664
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
