BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 29800599)

  • 1. Transcriptome analysis for the scale-down of a CHO cell fed-batch process.
    Alsayyari AA; Pan X; Dalm C; van der Veen JW; Vriezen N; Hageman JA; Wijffels RH; Martens DE
    J Biotechnol; 2018 Aug; 279():61-72. PubMed ID: 29800599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of TAP Ambr 250 disposable bioreactors, as a reliable scale-down model for biologics process development.
    Xu P; Clark C; Ryder T; Sparks C; Zhou J; Wang M; Russell R; Scott C
    Biotechnol Prog; 2017 Mar; 33(2):478-489. PubMed ID: 27977912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High throughput automated microbial bioreactor system used for clone selection and rapid scale-down process optimization.
    Velez-Suberbie ML; Betts JPJ; Walker KL; Robinson C; Zoro B; Keshavarz-Moore E
    Biotechnol Prog; 2018 Jan; 34(1):58-68. PubMed ID: 28748655
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Scale-down model qualification of ambr® 250 high-throughput mini-bioreactor system for two commercial-scale mAb processes.
    Manahan M; Nelson M; Cacciatore JJ; Weng J; Xu S; Pollard J
    Biotechnol Prog; 2019 Nov; 35(6):e2870. PubMed ID: 31207168
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation.
    Fan Y; Jimenez Del Val I; Müller C; Wagtberg Sen J; Rasmussen SK; Kontoravdi C; Weilguny D; Andersen MR
    Biotechnol Bioeng; 2015 Mar; 112(3):521-35. PubMed ID: 25220616
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
    Figueroa B; Ailor E; Osborne D; Hardwick JM; Reff M; Betenbaugh MJ
    Biotechnol Bioeng; 2007 Jul; 97(4):877-92. PubMed ID: 17099908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development.
    Janakiraman V; Kwiatkowski C; Kshirsagar R; Ryll T; Huang YM
    Biotechnol Prog; 2015; 31(6):1623-32. PubMed ID: 26317495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of a scale-up strategy for Chinese hamster ovary cell culture processes using the k
    Doi T; Kajihara H; Chuman Y; Kuwae S; Kaminagayoshi T; Omasa T
    Biotechnol Prog; 2020 Sep; 36(5):e3000. PubMed ID: 32298540
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ambr
    Warr SRC
    Methods Mol Biol; 2020; 2095():43-67. PubMed ID: 31858462
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteomic analysis of micro-scale bioreactors as scale-down model for a mAb producing CHO industrial fed-batch platform.
    Bertrand V; Vogg S; Villiger TK; Stettler M; Broly H; Soos M; Morbidelli M
    J Biotechnol; 2018 Aug; 279():27-36. PubMed ID: 29719200
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors.
    Tan JG; Lee YY; Wang T; Yap MG; Tan TW; Ng SK
    Biotechnol J; 2015 May; 10(5):790-800. PubMed ID: 25740626
    [TBL] [Abstract][Full Text] [Related]  

  • 12. S-Sulfocysteine simplifies fed-batch processes and increases the CHO specific productivity via anti-oxidant activity.
    Hecklau C; Pering S; Seibel R; Schnellbaecher A; Wehsling M; Eichhorn T; Hagen Jv; Zimmer A
    J Biotechnol; 2016 Jan; 218():53-63. PubMed ID: 26654938
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Automated dynamic fed-batch process and media optimization for high productivity cell culture process development.
    Lu F; Toh PC; Burnett I; Li F; Hudson T; Amanullah A; Li J
    Biotechnol Bioeng; 2013 Jan; 110(1):191-205. PubMed ID: 22767053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Segmented linear modeling of CHO fed-batch culture and its application to large scale production.
    Ben Yahia B; Gourevitch B; Malphettes L; Heinzle E
    Biotechnol Bioeng; 2017 Apr; 114(4):785-797. PubMed ID: 27869296
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Establishment and optimization of a high-throughput mimic perfusion model in ambr
    Jin L; Wang ZS; Cao Y; Sun RQ; Zhou H; Cao RY
    Biotechnol Lett; 2021 Feb; 43(2):423-433. PubMed ID: 33185810
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality.
    Yang WC; Lu J; Kwiatkowski C; Yuan H; Kshirsagar R; Ryll T; Huang YM
    Biotechnol Prog; 2014; 30(3):616-25. PubMed ID: 24574326
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transcriptomics as a tool for assessing the scalability of mammalian cell perfusion systems.
    Jayapal KP; Goudar CT
    Adv Biochem Eng Biotechnol; 2014; 139():227-43. PubMed ID: 23949697
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic engineering of CHO cells to alter lactate metabolism during fed-batch cultures.
    Toussaint C; Henry O; Durocher Y
    J Biotechnol; 2016 Jan; 217():122-31. PubMed ID: 26603123
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Application of bioreactor design principles and multivariate analysis for development of cell culture scale down models.
    Tescione L; Lambropoulos J; Paranandi MR; Makagiansar H; Ryll T
    Biotechnol Bioeng; 2015 Jan; 112(1):84-97. PubMed ID: 25042258
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The impact of pH inhomogeneities on CHO cell physiology and fed-batch process performance - two-compartment scale-down modelling and intracellular pH excursion.
    Brunner M; Braun P; Doppler P; Posch C; Behrens D; Herwig C; Fricke J
    Biotechnol J; 2017 Jul; 12(7):. PubMed ID: 28078826
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.