410 related articles for article (PubMed ID: 29803726)
1. Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.
Jurášek M; Černohorská M; Řehulka J; Spiwok V; Sulimenko T; Dráberová E; Darmostuk M; Gurská S; Frydrych I; Buriánová R; Ruml T; Hajdúch M; Bartůněk P; Dráber P; Džubák P; Drašar PB; Sedlák D
J Steroid Biochem Mol Biol; 2018 Oct; 183():68-79. PubMed ID: 29803726
[TBL] [Abstract][Full Text] [Related]
2. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
[TBL] [Abstract][Full Text] [Related]
3. An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics.
Rai A; Surolia A; Panda D
PLoS One; 2012; 7(8):e44311. PubMed ID: 22952952
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
Wang Z; Yang D; Mohanakrishnan AK; Fanwick PE; Nampoothiri P; Hamel E; Cushman M
J Med Chem; 2000 Jun; 43(12):2419-29. PubMed ID: 10882369
[TBL] [Abstract][Full Text] [Related]
5. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site.
Cushman M; He HM; Katzenellenbogen JA; Lin CM; Hamel E
J Med Chem; 1995 Jun; 38(12):2041-9. PubMed ID: 7783135
[TBL] [Abstract][Full Text] [Related]
7. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Guzmán EA; Xu Q; Pitts TP; Mitsuhashi KO; Baker C; Linley PA; Oestreicher J; Tendyke K; Winder PL; Suh EM; Wright AE
Int J Cancer; 2016 Nov; 139(9):2116-26. PubMed ID: 27376928
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of aryl dihydrothiazol acyl shikonin ester derivatives as anticancer agents through microtubule stabilization.
Lin HY; Li ZK; Bai LF; Baloch SK; Wang F; Qiu HY; Wang X; Qi JL; Yang RW; Wang XM; Yang YH
Biochem Pharmacol; 2015 Jul; 96(2):93-106. PubMed ID: 25957661
[TBL] [Abstract][Full Text] [Related]
9. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
Acharya BR; Chatterjee A; Ganguli A; Bhattacharya S; Chakrabarti G
Biochimie; 2014 Feb; 97():78-91. PubMed ID: 24113316
[TBL] [Abstract][Full Text] [Related]
10. Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.
Rathinasamy K; Jindal B; Asthana J; Singh P; Balaji PV; Panda D
BMC Cancer; 2010 May; 10():213. PubMed ID: 20482847
[TBL] [Abstract][Full Text] [Related]
11. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Du T; Lin S; Ji M; Xue N; Liu Y; Zhang Z; Zhang K; Zhang J; Zhang Y; Wang Q; Sheng L; Li Y; Lu D; Chen X; Xu H
Cancer Lett; 2020 Dec; 495():22-32. PubMed ID: 32931884
[TBL] [Abstract][Full Text] [Related]
12. Microtubule Targeting Agents as Cancer Chemotherapeutics: An Overview of Molecular Hybrids as Stabilizing and Destabilizing Agents.
Tangutur AD; Kumar D; Krishna KV; Kantevari S
Curr Top Med Chem; 2017; 17(22):2523-2537. PubMed ID: 28056738
[TBL] [Abstract][Full Text] [Related]
13. Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition.
Jurášek M; Řehulka J; Hrubá L; Ivanová A; Gurská S; Mokshyna O; Trousil P; Huml L; Polishchuk P; Hajdúch M; Drašar PB; Džubák P
Bioorg Chem; 2023 Feb; 131():106334. PubMed ID: 36592487
[TBL] [Abstract][Full Text] [Related]
14. Estradiol and testosterone have opposite effects on microtubule polymerization.
Kipp JL; Ramirez VD
Neuroendocrinology; 2003 Apr; 77(4):258-72. PubMed ID: 12766326
[TBL] [Abstract][Full Text] [Related]
15. A steroid derivative with paclitaxel-like effects on tubulin polymerization.
Verdier-Pinard P; Wang Z; Mohanakrishnan AK; Cushman M; Hamel E
Mol Pharmacol; 2000 Mar; 57(3):568-75. PubMed ID: 10692498
[TBL] [Abstract][Full Text] [Related]
16. 2-Methoxymethylestradiol: a new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics.
Brueggemeier RW; Bhat AS; Lovely CJ; Coughenour HD; Joomprabutra S; Weitzel DH; Vandre DD; Yusuf F; Burak WE
J Steroid Biochem Mol Biol; 2001 Aug; 78(2):145-56. PubMed ID: 11566439
[TBL] [Abstract][Full Text] [Related]
17. Indicine N-oxide binds to tubulin at a distinct site and inhibits the assembly of microtubules: a mechanism for its cytotoxic activity.
Appadurai P; Rathinasamy K
Toxicol Lett; 2014 Feb; 225(1):66-77. PubMed ID: 24300171
[TBL] [Abstract][Full Text] [Related]
18. Cellular, Biophysical and in Silico Binding Study of β-Estradiol-6-one 6- (O-carboxy methyl Oxime) with Tubulin in Search of Antimitotic Derivative of 2-Methoxy Estradiol.
Malla A; Bose A; Sur R; Gupta S
Cell Biochem Biophys; 2023 Jun; 81(2):269-283. PubMed ID: 37233844
[TBL] [Abstract][Full Text] [Related]
19. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
Viola G; Cecconet L; Leszl A; Basso G; Brun P; Salvador A; Dall'Acqua F; Diana P; Barraja P; Cirrincione G
Cancer Chemother Pharmacol; 2009 Nov; 64(6):1235-51. PubMed ID: 19363609
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
