BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 29803840)

  • 1. Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling.
    Verheijen M; Schrooders Y; Gmuender H; Nudischer R; Clayton O; Hynes J; Niederer S; Cordes H; Kuepfer L; Kleinjans J; Caiment F
    Toxicol Lett; 2018 Sep; 294():184-192. PubMed ID: 29803840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment.
    Chaudhari U; Nemade H; Wagh V; Gaspar JA; Ellis JK; Srinivasan SP; Spitkovski D; Nguemo F; Louisse J; Bremer S; Hescheler J; Keun HC; Hengstler JG; Sachinidis A
    Arch Toxicol; 2016 Nov; 90(11):2763-2777. PubMed ID: 26537877
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells.
    Takeda M; Miyagawa S; Fukushima S; Saito A; Ito E; Harada A; Matsuura R; Iseoka H; Sougawa N; Mochizuki-Oda N; Matsusaki M; Akashi M; Sawa Y
    Tissue Eng Part C Methods; 2018 Jan; 24(1):56-67. PubMed ID: 28967302
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes.
    Chaudhari U; Ellis JK; Wagh V; Nemade H; Hescheler J; Keun HC; Sachinidis A
    Amino Acids; 2017 Dec; 49(12):1955-1963. PubMed ID: 28421296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plasmatic and chamber-specific modulation of cardiac microRNAs in an acute model of DOX-induced cardiotoxicity.
    Gioffré S; Ricci V; Vavassori C; Ruggeri C; Chiesa M; Alfieri I; Zorzan S; Buzzetti M; Milano G; Scopece A; Castiglioni L; Sironi L; Pompilio G; Colombo GI; D'Alessandra Y
    Biomed Pharmacother; 2019 Feb; 110():1-8. PubMed ID: 30453253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dosing depending on SIRT3 activity attenuates doxorubicin-induced cardiotoxicity via elevated tolerance against mitochondrial dysfunction and oxidative stress.
    Yang N; Ma H; Jiang Z; Niu L; Zhang X; Liu Y; Wang Y; Cheng S; Deng Y; Qi H; Wang Z
    Biochem Biophys Res Commun; 2019 Sep; 517(1):111-117. PubMed ID: 31303273
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes.
    Chaudhari U; Nemade H; Gaspar JA; Hescheler J; Hengstler JG; Sachinidis A
    Arch Toxicol; 2016 Dec; 90(12):3087-3098. PubMed ID: 26842497
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.
    Cui N; Wu F; Lu WJ; Bai R; Ke B; Liu T; Li L; Lan F; Cui M
    J Cell Mol Med; 2019 Jul; 23(7):4627-4639. PubMed ID: 31106979
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Doxorubicin induces cardiomyocyte pyroptosis via the TINCR-mediated posttranscriptional stabilization of NLR family pyrin domain containing 3.
    Meng L; Lin H; Zhang J; Lin N; Sun Z; Gao F; Luo H; Ni T; Luo W; Chi J; Guo H
    J Mol Cell Cardiol; 2019 Nov; 136():15-26. PubMed ID: 31445005
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes.
    Maillet A; Tan K; Chai X; Sadananda SN; Mehta A; Ooi J; Hayden MR; Pouladi MA; Ghosh S; Shim W; Brunham LR
    Sci Rep; 2016 May; 6():25333. PubMed ID: 27142468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. miRNA Expression Profiles in Isolated Ventricular Cardiomyocytes: Insights into Doxorubicin-Induced Cardiotoxicity.
    Domínguez Romero Y; Montoya Ortiz G; Novoa Herrán S; Osorio Mendez J; Gomez Grosso LA
    Int J Mol Sci; 2024 May; 25(10):. PubMed ID: 38791311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Long noncoding RNA LINC00339 aggravates doxorubicin-induced cardiomyocyte apoptosis by targeting MiR-484.
    Li J; Li L; Li X; Wu S
    Biochem Biophys Res Commun; 2018 Sep; 503(4):3038-3043. PubMed ID: 30170730
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity.
    Koleini N; Kardami E
    Oncotarget; 2017 Jul; 8(28):46663-46680. PubMed ID: 28445146
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Biophysical Systems Approach to Identifying the Pathways of Acute and Chronic Doxorubicin Mitochondrial Cardiotoxicity.
    de Oliveira BL; Niederer S
    PLoS Comput Biol; 2016 Nov; 12(11):e1005214. PubMed ID: 27870850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitigation of doxorubicin-induced cardiotoxicity by dichloroacetate: potential roles of restoration of PGC-1α/SIRT3 signaling and suppression of oxidative stress and apoptosis.
    Saleh MF; Elsayad ME; Goda AE
    Eur Rev Med Pharmacol Sci; 2021 Nov; 25(21):6573-6584. PubMed ID: 34787860
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell-derived cardiomyocytes.
    Louisse J; Wüst RCI; Pistollato F; Palosaari T; Barilari M; Macko P; Bremer S; Prieto P
    Toxicol In Vitro; 2017 Aug; 42():182-190. PubMed ID: 28456566
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autophagic dysregulation in doxorubicin cardiomyopathy.
    Bartlett JJ; Trivedi PC; Pulinilkunnil T
    J Mol Cell Cardiol; 2017 Mar; 104():1-8. PubMed ID: 28108310
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats.
    Pereira GC; Pereira SP; Pereira FB; Lourenço N; Lumini JA; Pereira CV; Bjork JA; Magalhães J; Ascensão A; Wieckowski MR; Moreno AJ; Wallace KB; Oliveira PJ
    Toxicol Sci; 2019 May; 169(1):137-150. PubMed ID: 30698778
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity.
    Vaidya TR; Mody H; Franco YL; Brown A; Ait-Oudhia S
    AAPS J; 2021 Jan; 23(1):18. PubMed ID: 33404976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of COX5A protects H9c2 cells against doxorubicin-induced cardiotoxicity.
    Zhang P; Chen Z; Lu D; Wu Y; Fan M; Qian J; Ge J
    Biochem Biophys Res Commun; 2020 Mar; 524(1):43-49. PubMed ID: 31980176
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.