BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 29842835)

  • 1. Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors.
    Puhl-Rubio AC; Stashko MA; Wang H; Hardy PB; Tyagi V; Li B; Wang X; Kireev D; Jessen HJ; Frye SV; Shears SB; Pearce KH
    SLAS Discov; 2018 Oct; 23(9):982-988. PubMed ID: 29842835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors.
    Baughman BM; Wang H; An Y; Kireev D; Stashko MA; Jessen HJ; Pearce KH; Frye SV; Shears SB
    PLoS One; 2016; 11(10):e0164378. PubMed ID: 27736936
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and characterization of novel isoform-selective IP6K1 inhibitors.
    Wormald MM; Ernst G; Wei H; Barrow JC
    Bioorg Med Chem Lett; 2019 Oct; 29(19):126628. PubMed ID: 31445853
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TNP and its analogs: Modulation of IP6K and CYP3A4 inhibition.
    Lee S; Park BB; Kwon H; Kim V; Jeon JS; Lee R; Subedi M; Lim T; Ha H; An D; Kim J; Kim D; Kim SK; Kim S; Byun Y
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):269-279. PubMed ID: 34894957
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KO of 5-InsP
    Gu C; Nguyen HN; Ganini D; Chen Z; Jessen HJ; Gu Z; Wang H; Shears SB
    Proc Natl Acad Sci U S A; 2017 Nov; 114(45):11968-11973. PubMed ID: 29078269
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates.
    Padmanabhan U; Dollins DE; Fridy PC; York JD; Downes CP
    J Biol Chem; 2009 Apr; 284(16):10571-82. PubMed ID: 19208622
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
    Gu C; Stashko MA; Puhl-Rubio AC; Chakraborty M; Chakraborty A; Frye SV; Pearce KH; Wang X; Shears SB; Wang H
    J Med Chem; 2019 Feb; 62(3):1443-1454. PubMed ID: 30624931
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase- and lipase inhibitors of inositide metabolism deplete IP
    Rajasekaran SS; Illies C; Shears SB; Wang H; Ayala TS; Martins JO; Daré E; Berggren PO; Barker CJ
    Cell Signal; 2018 Jan; 42():127-133. PubMed ID: 29042286
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio.
    Wundenberg T; Grabinski N; Lin H; Mayr GW
    Biochem J; 2014 Aug; 462(1):173-84. PubMed ID: 24865181
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals.
    Moritoh Y; Abe SI; Akiyama H; Kobayashi A; Koyama R; Hara R; Kasai S; Watanabe M
    Nat Commun; 2021 Aug; 12(1):4847. PubMed ID: 34381031
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of flavonoid-based IP6K2 inhibitors.
    Ahn M; Park SE; Choi J; Choi J; Choi D; An D; Jeon H; Oh S; Lee K; Kim J; Jang J; Kim S; Byun Y
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2193866. PubMed ID: 37013838
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases.
    Mukherjee S; Haubner J; Chakraborty A
    Molecules; 2020 Mar; 25(6):. PubMed ID: 32204420
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.
    Gu C; Nguyen HN; Hofer A; Jessen HJ; Dai X; Wang H; Shears SB
    J Biol Chem; 2017 Mar; 292(11):4544-4555. PubMed ID: 28126903
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family.
    Wang H; DeRose EF; London RE; Shears SB
    Nat Commun; 2014 Jun; 5():4178. PubMed ID: 24956979
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective inhibition of inositol hexakisphosphate kinases (IP6Ks) enhances mesenchymal stem cell engraftment and improves therapeutic efficacy for myocardial infarction.
    Zhang Z; Liang D; Gao X; Zhao C; Qin X; Xu Y; Su T; Sun D; Li W; Wang H; Liu B; Cao F
    Basic Res Cardiol; 2014 Jul; 109(4):417. PubMed ID: 24847908
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inositol phosphate kinases: Expanding the biological significance of the universal core of the protein kinase fold.
    Shears SB; Wang H
    Adv Biol Regul; 2019 Jan; 71():118-127. PubMed ID: 30392847
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity.
    Wormald M; Liao G; Kimos M; Barrow J; Wei H
    PLoS One; 2017; 12(11):e0188852. PubMed ID: 29186181
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
    Aguirre T; Dornan GL; Hostachy S; Neuenschwander M; Seyffarth C; Haucke V; Schütz A; von Kries JP; Fiedler D
    Elife; 2023 Oct; 12():. PubMed ID: 37843983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase.
    Fu C; Xu J; Cheng W; Rojas T; Chin AC; Snowman AM; Harraz MM; Snyder SH
    Proc Natl Acad Sci U S A; 2017 Feb; 114(8):2036-2041. PubMed ID: 28154132
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway.
    Sarmah B; Wente SR
    Proc Natl Acad Sci U S A; 2010 Nov; 107(46):19921-6. PubMed ID: 20980661
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.