BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 29842835)

  • 41. Systematic Profiling and Evaluation of Structure-based Kinase-Inhibitor Interactome in Cervical Cancer by Integrating In Silico Analyses and In Vitro Assays at Molecular and Cellular Levels.
    Zhu LX; Liu Q; Hua YF; Yang N; Zhang XG; Ding X
    Comput Biol Chem; 2019 Jun; 80():324-332. PubMed ID: 31078911
    [TBL] [Abstract][Full Text] [Related]  

  • 42. p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.
    Koldobskiy MA; Chakraborty A; Werner JK; Snowman AM; Juluri KR; Vandiver MS; Kim S; Heletz S; Snyder SH
    Proc Natl Acad Sci U S A; 2010 Dec; 107(49):20947-51. PubMed ID: 21078964
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Inositol Hexakisphosphate Kinase-3 Regulates the Morphology and Synapse Formation of Cerebellar Purkinje Cells via Spectrin/Adducin.
    Fu C; Xu J; Li RJ; Crawford JA; Khan AB; Ma TM; Cha JY; Snowman AM; Pletnikov MV; Snyder SH
    J Neurosci; 2015 Aug; 35(31):11056-67. PubMed ID: 26245967
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor.
    Voglmaier SM; Bembenek ME; Kaplin AI; Dormán G; Olszewski JD; Prestwich GD; Snyder SH
    Proc Natl Acad Sci U S A; 1996 Apr; 93(9):4305-10. PubMed ID: 8633060
    [TBL] [Abstract][Full Text] [Related]  

  • 45. TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway.
    Ghoshal S; Zhu Q; Asteian A; Lin H; Xu H; Ernst G; Barrow JC; Xu B; Cameron MD; Kamenecka TM; Chakraborty A
    Mol Metab; 2016 Oct; 5(10):903-917. PubMed ID: 27689003
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP
    Sahu S; Gordon J; Gu C; Sobhany M; Fiedler D; Stanley RE; Shears SB
    Biomolecules; 2023 Jan; 13(1):. PubMed ID: 36671538
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors.
    Heitmann T; Liao G; de León P; Ernst G; Buchler I; Wei H; Shlevkov E; Brown D; Fitzek M; Collier M; Smith DM; Barrow JC
    ACS Med Chem Lett; 2023 Dec; 14(12):1760-1766. PubMed ID: 38116421
    [TBL] [Abstract][Full Text] [Related]  

  • 48. A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP).
    Vainshtein I; Silveria S; Kaul P; Rouhani R; Eglen RM; Wang J
    J Biomol Screen; 2002 Dec; 7(6):507-14. PubMed ID: 14599348
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure.
    Park H; Chi O; Kim J; Hong S
    J Chem Inf Model; 2011 Nov; 51(11):2986-93. PubMed ID: 22017333
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Inositol pyrophosphates: between signalling and metabolism.
    Wilson MS; Livermore TM; Saiardi A
    Biochem J; 2013 Jun; 452(3):369-79. PubMed ID: 23725456
    [TBL] [Abstract][Full Text] [Related]  

  • 51. The Role of Inositol Hexakisphosphate Kinase in the Central Nervous System.
    Heitmann T; Barrow JC
    Biomolecules; 2023 Aug; 13(9):. PubMed ID: 37759717
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Control of XPR1-dependent cellular phosphate efflux by InsP
    Li X; Gu C; Hostachy S; Sahu S; Wittwer C; Jessen HJ; Fiedler D; Wang H; Shears SB
    Proc Natl Acad Sci U S A; 2020 Feb; 117(7):3568-3574. PubMed ID: 32019887
    [TBL] [Abstract][Full Text] [Related]  

  • 53. New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway.
    Nehmé R; Nehmé H; Saurat T; de-Tauzia ML; Buron F; Lafite P; Verrelle P; Chautard E; Morin P; Routier S; Bénédetti H
    Anal Bioanal Chem; 2014 Jun; 406(15):3743-54. PubMed ID: 24817345
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The design, annotation, and application of a kinase-targeted library.
    Xi H; Lunney EA
    Methods Mol Biol; 2011; 685():279-91. PubMed ID: 20981529
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.
    Comess KM; Sun C; Abad-Zapatero C; Goedken ER; Gum RJ; Borhani DW; Argiriadi M; Groebe DR; Jia Y; Clampit JE; Haasch DL; Smith HT; Wang S; Song D; Coen ML; Cloutier TE; Tang H; Cheng X; Quinn C; Liu B; Xin Z; Liu G; Fry EH; Stoll V; Ng TI; Banach D; Marcotte D; Burns DJ; Calderwood DJ; Hajduk PJ
    ACS Chem Biol; 2011 Mar; 6(3):234-44. PubMed ID: 21090814
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants.
    Desai M; Rangarajan P; Donahue JL; Williams SP; Land ES; Mandal MK; Phillippy BQ; Perera IY; Raboy V; Gillaspy GE
    Plant J; 2014 Nov; 80(4):642-53. PubMed ID: 25231822
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2.
    Chakraborty A; Werner JK; Koldobskiy MA; Mustafa AK; Juluri KR; Pietropaoli J; Snowman AM; Snyder SH
    Proc Natl Acad Sci U S A; 2011 Feb; 108(6):2205-9. PubMed ID: 21262846
    [TBL] [Abstract][Full Text] [Related]  

  • 58. The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment.
    Weaver JD; Wang H; Shears SB
    Biosci Rep; 2013 Feb; 33(2):e00022. PubMed ID: 23240582
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.
    Sharlow ER; Mustata Wilson G; Close D; Leimgruber S; Tandon M; Reed RB; Shun TY; Wang QJ; Wipf P; Lazo JS
    PLoS One; 2011; 6(10):e25134. PubMed ID: 21998636
    [TBL] [Abstract][Full Text] [Related]  

  • 60. A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    Gao Y; Davies SP; Augustin M; Woodward A; Patel UA; Kovelman R; Harvey KJ
    Biochem J; 2013 Apr; 451(2):313-28. PubMed ID: 23398362
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.