BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 29844464)

  • 1. Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition.
    Siddiqui FA; Prakasam G; Chattopadhyay S; Rehman AU; Padder RA; Ansari MA; Irshad R; Mangalhara K; Bamezai RNK; Husain M; Ali SM; Iqbal MA
    Sci Rep; 2018 May; 8(1):8323. PubMed ID: 29844464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
    Iqbal MA; Siddiqui FA; Gupta V; Chattopadhyay S; Gopinath P; Kumar B; Manvati S; Chaman N; Bamezai RN
    Mol Cancer; 2013 Jul; 12():72. PubMed ID: 23837608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
    Sun Q; Chen X; Ma J; Peng H; Wang F; Zha X; Wang Y; Jing Y; Yang H; Chen R; Chang L; Zhang Y; Goto J; Onda H; Chen T; Wang MR; Lu Y; You H; Kwiatkowski D; Zhang H
    Proc Natl Acad Sci U S A; 2011 Mar; 108(10):4129-34. PubMed ID: 21325052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.
    Iqbal MA; Bamezai RN
    PLoS One; 2012; 7(5):e36764. PubMed ID: 22574221
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture.
    Dong T; Yan Y; Chai H; Chen S; Xiong X; Sun D; Yu Y; Deng L; Cheng F
    Biomed Pharmacother; 2015 Feb; 69():277-84. PubMed ID: 25661370
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucose restriction reverses the Warburg effect and modulates PKM2 and mTOR expression in breast cancer cell lines.
    Tahtouh R; Wardi L; Sarkis R; Hachem R; Raad I; El Zein N; Hilal G
    Cell Mol Biol (Noisy-le-grand); 2019 Sep; 65(7):26-33. PubMed ID: 31880514
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer.
    Yadav S; Bhagat SD; Gupta A; Samaiya A; Srivastava A; Shukla S
    BMC Cancer; 2019 Nov; 19(1):1031. PubMed ID: 31675998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism.
    Wang HJ; Hsieh YJ; Cheng WC; Lin CP; Lin YS; Yang SF; Chen CC; Izumiya Y; Yu JS; Kung HJ; Wang WC
    Proc Natl Acad Sci U S A; 2014 Jan; 111(1):279-84. PubMed ID: 24344305
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells.
    Dey P; Kundu A; Sachan R; Park JH; Ahn MY; Yoon K; Lee J; Kim ND; Kim IS; Lee BM; Kim HS
    Cell Physiol Biochem; 2019; 52(6):1535-1552. PubMed ID: 31135122
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N6-isopentenyladenosine inhibits aerobic glycolysis in glioblastoma cells by targeting PKM2 expression and activity.
    Pagano C; Coppola L; Navarra G; Avilia G; Savarese B; Torelli G; Bruzzaniti S; Piemonte E; Galgani M; Laezza C; Bifulco M
    FEBS Open Bio; 2024 May; 14(5):843-854. PubMed ID: 38514913
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells.
    Huang L; Yu Z; Zhang T; Zhao X; Huang G
    PLoS One; 2014; 9(3):e92949. PubMed ID: 24658033
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms.
    Liu J; Wu N; Ma L; Liu M; Liu G; Zhang Y; Lin X
    PLoS One; 2014; 9(3):e91606. PubMed ID: 24626155
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Down-regulation of miR-214 inhibits proliferation and glycolysis in non-small-cell lung cancer cells via down-regulating the expression of hexokinase 2 and pyruvate kinase isozyme M2.
    Zhang K; Zhang M; Jiang H; Liu F; Liu H; Li Y
    Biomed Pharmacother; 2018 Sep; 105():545-552. PubMed ID: 29886375
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions.
    Bi YH; Han WQ; Li RF; Wang YJ; Du ZS; Wang XJ; Jiang Y
    World J Gastroenterol; 2019 Apr; 25(16):1936-1949. PubMed ID: 31086462
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical cancer.
    Zhu H; Wu J; Zhang W; Luo H; Shen Z; Cheng H; Zhu X
    Sci Rep; 2016 Aug; 6():30788. PubMed ID: 27492148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells.
    Park JH; Kundu A; Lee SH; Jiang C; Lee SH; Kim YS; Kyung SY; Park SH; Kim HS
    Int J Biol Sci; 2021; 17(8):1895-1908. PubMed ID: 34131394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKM2 Is Essential for Bladder Cancer Growth and Maintenance.
    Xia Y; Wang X; Liu Y; Shapiro E; Lepor H; Tang MS; Sun TT; Wu XR
    Cancer Res; 2022 Feb; 82(4):571-585. PubMed ID: 34903602
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IGF1 regulates PKM2 function through Akt phosphorylation.
    Salani B; Ravera S; Amaro A; Salis A; Passalacqua M; Millo E; Damonte G; Marini C; Pfeffer U; Sambuceti G; Cordera R; Maggi D
    Cell Cycle; 2015; 14(10):1559-67. PubMed ID: 25790097
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells.
    Yu Z; Zhao X; Huang L; Zhang T; Yang F; Xie L; Song S; Miao P; Zhao L; Sun X; Liu J; Huang G
    J Biol Chem; 2013 Dec; 288(49):35406-16. PubMed ID: 24142698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ECM1 promotes the Warburg effect through EGF-mediated activation of PKM2.
    Lee KM; Nam K; Oh S; Lim J; Lee T; Shin I
    Cell Signal; 2015 Feb; 27(2):228-35. PubMed ID: 25446258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.