These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

367 related articles for article (PubMed ID: 29845435)

  • 1. Molecular insight on the non-covalent interactions between carbapenems and L,D-transpeptidase 2 from Mycobacterium tuberculosis: ONIOM study.
    Ntombela T; Fakhar Z; Ibeji CU; Govender T; Maguire GEM; Lamichhane G; Kruger HG; Honarparvar B
    J Comput Aided Mol Des; 2018 Jun; 32(6):687-701. PubMed ID: 29845435
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The catalytic role of water in the binding site of l,d-transpeptidase 2 within acylation mechanism: A QM/MM (ONIOM) modelling.
    Ibeji CU; Tolufashe GF; Ntombela T; Govender T; Maguire GEM; Lamichhane G; Kruger HG; Honarparvar B
    Tuberculosis (Edinb); 2018 Dec; 113():222-230. PubMed ID: 30514506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt
    Bianchet MA; Pan YH; Basta LAB; Saavedra H; Lloyd EP; Kumar P; Mattoo R; Townsend CA; Lamichhane G
    BMC Biochem; 2017 May; 18(1):8. PubMed ID: 28545389
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition mechanism of L,D-transpeptidase 5 in presence of the β-lactams using ONIOM method.
    Tolufashe GF; Sabe VT; Ibeji CU; Lawal MM; Govender T; Maguire GEM; Lamichhane G; Kruger HG; Honarparvar B
    J Mol Graph Model; 2019 Mar; 87():204-210. PubMed ID: 30554066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains.
    Kim HS; Kim J; Im HN; Yoon JY; An DR; Yoon HJ; Kim JY; Min HK; Kim SJ; Lee JY; Han BW; Suh SW
    Acta Crystallogr D Biol Crystallogr; 2013 Mar; 69(Pt 3):420-31. PubMed ID: 23519417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis.
    Correale S; Ruggiero A; Capparelli R; Pedone E; Berisio R
    Acta Crystallogr D Biol Crystallogr; 2013 Sep; 69(Pt 9):1697-706. PubMed ID: 23999293
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis.
    Li WJ; Li DF; Hu YL; Zhang XE; Bi LJ; Wang DC
    Cell Res; 2013 May; 23(5):728-31. PubMed ID: 23588382
    [No Abstract]   [Full Text] [Related]  

  • 8. Structural and biochemical analyses of the Ldt
    Wang X; Gu X; Zhang C; Zhao F; Deng K
    Biochem Biophys Res Commun; 2020 Feb; 523(1):6-9. PubMed ID: 31822344
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure and Inhibitor Specificity of L,D-Transpeptidase (LdtMt2) from Mycobacterium tuberculosis and Antibiotic Resistance: Calcium Binding Promotes Dimer Formation.
    Gokulan K; Khare S; Cerniglia CE; Foley SL; Varughese KI
    AAPS J; 2018 Mar; 20(2):44. PubMed ID: 29524047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 1-β-methyl group confers a lower affinity of l,d-transpeptidase Ldt
    Zhao F; Hou YJ; Zhang Y; Wang DC; Li DF
    Biochem Biophys Res Commun; 2019 Mar; 510(2):254-260. PubMed ID: 30686533
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Simulating the inhibition reaction of Mycobacterium tuberculosis L,D-transpeptidase 2 by carbapenems.
    Silva JR; Govender T; Maguire GE; Kruger HG; Lameira J; Roitberg AE; Alves CN
    Chem Commun (Camb); 2015 Aug; 51(63):12560-2. PubMed ID: 26153571
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding and processing of β-lactam antibiotics by the transpeptidase Ldt
    Steiner EM; Schneider G; Schnell R
    FEBS J; 2017 Mar; 284(5):725-741. PubMed ID: 28075068
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2.
    Silva JR; Bishai WR; Govender T; Lamichhane G; Maguire GE; Kruger HG; Lameira J; Alves CN
    J Biomol Struct Dyn; 2016; 34(2):304-17. PubMed ID: 25762064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inactivation of Mycobacterium tuberculosis l,d-transpeptidase LdtMt₁ by carbapenems and cephalosporins.
    Dubée V; Triboulet S; Mainardi JL; Ethève-Quelquejeu M; Gutmann L; Marie A; Dubost L; Hugonnet JE; Arthur M
    Antimicrob Agents Chemother; 2012 Aug; 56(8):4189-95. PubMed ID: 22615283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of potent L,D-transpeptidase 5 inhibitors for Mycobacterium tuberculosis as potential anti-TB leads: virtual screening and molecular dynamics simulations.
    Sabe VT; Tolufashe GF; Ibeji CU; Maseko SB; Govender T; Maguire GEM; Lamichhane G; Honarparvar B; Kruger HG
    J Mol Model; 2019 Oct; 25(11):328. PubMed ID: 31656981
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the binding free energies of FDA approved drugs against subtype B and C-SA HIV PR: ONIOM approach.
    Sanusi ZK; Govender T; Maguire GEM; Maseko SB; Lin J; Kruger HG; Honarparvar B
    J Mol Graph Model; 2017 Sep; 76():77-85. PubMed ID: 28711760
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic insight on the inhibition of D, D-carboxypeptidase from
    Ntombela T; Seupersad A; Maseko S; Ibeji CU; Tolufashe G; Maphumulo SI; Naicker T; Baijnath S; Maguire GEM; Govender T; Lamichhane G; Honarparvar B; Kruger HG
    J Biomol Struct Dyn; 2022 Oct; 40(17):7645-7655. PubMed ID: 33719919
    [No Abstract]   [Full Text] [Related]  

  • 18. Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2.
    Erdemli SB; Gupta R; Bishai WR; Lamichhane G; Amzel LM; Bianchet MA
    Structure; 2012 Dec; 20(12):2103-15. PubMed ID: 23103390
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors.
    Gupta R; Al-Kharji NMSA; Alqurafi MA; Nguyen TQ; Chai W; Quan P; Malhotra R; Simcox BS; Mortimer P; Brammer Basta LA; Rohde KH; Buynak JD
    ACS Infect Dis; 2021 Aug; 7(8):2425-2436. PubMed ID: 34191496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the Mycobacterium tuberculosis transpeptidase Ldt
    de Munnik M; Lohans CT; Lang PA; Langley GW; Malla TR; Tumber A; Schofield CJ; Brem J
    Chem Commun (Camb); 2019 Aug; 55(69):10214-10217. PubMed ID: 31380528
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.