These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 29855382)

  • 1. Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.
    Nicholson AM; Zhou X; Perkerson RB; Parsons TM; Chew J; Brooks M; DeJesus-Hernandez M; Finch NA; Matchett BJ; Kurti A; Jansen-West KR; Perkerson E; Daughrity L; Castanedes-Casey M; Rousseau L; Phillips V; Hu F; Gendron TF; Murray ME; Dickson DW; Fryer JD; Petrucelli L; Rademakers R
    Acta Neuropathol Commun; 2018 May; 6(1):42. PubMed ID: 29855382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.
    Gallagher MD; Suh E; Grossman M; Elman L; McCluskey L; Van Swieten JC; Al-Sarraj S; Neumann M; Gelpi E; Ghetti B; Rohrer JD; Halliday G; Van Broeckhoven C; Seilhean D; Shaw PJ; Frosch MP; Alafuzoff I; Antonell A; Bogdanovic N; Brooks W; Cairns NJ; Cooper-Knock J; Cotman C; Cras P; Cruts M; De Deyn PP; DeCarli C; Dobson-Stone C; Engelborghs S; Fox N; Galasko D; Gearing M; Gijselinck I; Grafman J; Hartikainen P; Hatanpaa KJ; Highley JR; Hodges J; Hulette C; Ince PG; Jin LW; Kirby J; Kofler J; Kril J; Kwok JB; Levey A; Lieberman A; Llado A; Martin JJ; Masliah E; McDermott CJ; McKee A; McLean C; Mead S; Miller CA; Miller J; Munoz DG; Murrell J; Paulson H; Piguet O; Rossor M; Sanchez-Valle R; Sano M; Schneider J; Silbert LC; Spina S; van der Zee J; Van Langenhove T; Warren J; Wharton SB; White CL; Woltjer RL; Trojanowski JQ; Lee VM; Van Deerlin V; Chen-Plotkin AS
    Acta Neuropathol; 2014 Mar; 127(3):407-18. PubMed ID: 24442578
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia.
    van Blitterswijk M; Mullen B; Nicholson AM; Bieniek KF; Heckman MG; Baker MC; DeJesus-Hernandez M; Finch NA; Brown PH; Murray ME; Hsiung GY; Stewart H; Karydas AM; Finger E; Kertesz A; Bigio EH; Weintraub S; Mesulam M; Hatanpaa KJ; White CL; Strong MJ; Beach TG; Wszolek ZK; Lippa C; Caselli R; Petrucelli L; Josephs KA; Parisi JE; Knopman DS; Petersen RC; Mackenzie IR; Seeley WW; Grinberg LT; Miller BL; Boylan KB; Graff-Radford NR; Boeve BF; Dickson DW; Rademakers R
    Acta Neuropathol; 2014 Mar; 127(3):397-406. PubMed ID: 24385136
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes.
    Busch JI; Unger TL; Jain N; Tyler Skrinak R; Charan RA; Chen-Plotkin AS
    Hum Mol Genet; 2016 Jul; 25(13):2681-2697. PubMed ID: 27126638
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72.
    Davidson YS; Barker H; Robinson AC; Thompson JC; Harris J; Troakes C; Smith B; Al-Saraj S; Shaw C; Rollinson S; Masuda-Suzukake M; Hasegawa M; Pickering-Brown S; Snowden JS; Mann DM
    Acta Neuropathol Commun; 2014 Jun; 2():70. PubMed ID: 24950788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients.
    Mordes DA; Prudencio M; Goodman LD; Klim JR; Moccia R; Limone F; Pietilainen O; Chowdhary K; Dickson DW; Rademakers R; Bonini NM; Petrucelli L; Eggan K
    Acta Neuropathol Commun; 2018 Jul; 6(1):55. PubMed ID: 29973287
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient mice.
    Zhou X; Brooks M; Jiang P; Koga S; Zuberi AR; Baker MC; Parsons TM; Castanedes-Casey M; Phillips V; Librero AL; Kurti A; Fryer JD; Bu G; Lutz C; Dickson DW; Rademakers R
    EMBO Rep; 2020 Oct; 21(10):e50197. PubMed ID: 32761777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defining the association of TMEM106B variants among frontotemporal lobar degeneration patients with GRN mutations and C9orf72 repeat expansions.
    Lattante S; Le Ber I; Galimberti D; Serpente M; Rivaud-Péchoux S; Camuzat A; Clot F; Fenoglio C; ; Scarpini E; Brice A; Kabashi E
    Neurobiol Aging; 2014 Nov; 35(11):2658.e1-2658.e5. PubMed ID: 25085782
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency.
    Zhou X; Sun L; Brady OA; Murphy KA; Hu F
    Acta Neuropathol Commun; 2017 Jan; 5(1):9. PubMed ID: 28126008
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion.
    Bieniek KF; Murray ME; Rutherford NJ; Castanedes-Casey M; DeJesus-Hernandez M; Liesinger AM; Baker MC; Boylan KB; Rademakers R; Dickson DW
    Acta Neuropathol; 2013 Feb; 125(2):289-302. PubMed ID: 23053135
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The association between repeat number in C9orf72 and phenotypic variability in Turkish patients with frontotemporal lobar degeneration.
    Erzurumluoglu E; Cilingir O; Ozbabalik Adapinar BD; Bilgic B; Kocagil S; Ozen H; Durak Aras B; Yenilmez C; Artan S
    Neurobiol Aging; 2019 Apr; 76():216.e1-216.e7. PubMed ID: 30685122
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype.
    Cooper-Knock J; Shaw PJ; Kirby J
    Acta Neuropathol; 2014 Mar; 127(3):333-45. PubMed ID: 24493408
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lack of a protective effect of the Tmem106b "protective SNP" in the Grn knockout mouse model for frontotemporal lobar degeneration.
    Cabron AS; Borgmeyer U; Richter J; Peisker H; Gutbrod K; Dörmann P; Capell A; Damme M
    Acta Neuropathol Commun; 2023 Jan; 11(1):21. PubMed ID: 36707901
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells.
    Leskelä S; Huber N; Hoffmann D; Rostalski H; Remes AM; Takalo M; Hiltunen M; Haapasalo A
    Biochim Biophys Acta Mol Cell Res; 2021 Jun; 1868(7):119021. PubMed ID: 33775797
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Viral delivery of
    Herranz-Martin S; Chandran J; Lewis K; Mulcahy P; Higginbottom A; Walker C; Valenzuela IMY; Jones RA; Coldicott I; Iannitti T; Akaaboune M; El-Khamisy SF; Gillingwater TH; Shaw PJ; Azzouz M
    Dis Model Mech; 2017 Jul; 10(7):859-868. PubMed ID: 28550099
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease.
    Sakae N; Bieniek KF; Zhang YJ; Ross K; Gendron TF; Murray ME; Rademakers R; Petrucelli L; Dickson DW
    Acta Neuropathol Commun; 2018 Jul; 6(1):63. PubMed ID: 30029693
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain.
    Busch JI; Martinez-Lage M; Ashbridge E; Grossman M; Van Deerlin VM; Hu F; Lee VM; Trojanowski JQ; Chen-Plotkin AS
    Acta Neuropathol Commun; 2013 Jul; 1():36. PubMed ID: 24252750
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways.
    Chen-Plotkin AS; Unger TL; Gallagher MD; Bill E; Kwong LK; Volpicelli-Daley L; Busch JI; Akle S; Grossman M; Van Deerlin V; Trojanowski JQ; Lee VM
    J Neurosci; 2012 Aug; 32(33):11213-27. PubMed ID: 22895706
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.
    Werner G; Damme M; Schludi M; Gnörich J; Wind K; Fellerer K; Wefers B; Wurst W; Edbauer D; Brendel M; Haass C; Capell A
    EMBO Rep; 2020 Oct; 21(10):e50241. PubMed ID: 32929860
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.