160 related articles for article (PubMed ID: 29856012)
1. Assessing Autophagic Activity and Aggregate Formation of Mutant Huntingtin in Mammalian Cells.
Stamatakou E; Zhu Y; Rubinsztein DC
Methods Mol Biol; 2018; 1780():17-29. PubMed ID: 29856012
[TBL] [Abstract][Full Text] [Related]
2. Midazolam Enhances Mutant Huntingtin Protein Accumulation via Impairment of Autophagic Degradation In Vitro.
Zhang J; Dai W; Geng P; Zhang L; Tan Q; Cheng D; Wei P; Yang Z; Zhang L; Gu E; Xu G; Liang C; Liu X
Cell Physiol Biochem; 2018; 48(2):683-691. PubMed ID: 30025395
[TBL] [Abstract][Full Text] [Related]
3. Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
Chen Y; Xu S; Wang N; Ma Q; Peng P; Yu Y; Zhang L; Ying Z; Wang H
Neurotox Res; 2019 Jul; 36(1):108-116. PubMed ID: 30924108
[TBL] [Abstract][Full Text] [Related]
4. Glyceraldehyde-3-Phosphate Dehydrogenase Facilitates Macroautophagic Degradation of Mutant Huntingtin Protein Aggregates.
Chaudhary S; Dhiman A; Dilawari R; Chaubey GK; Talukdar S; Modanwal R; Patidar A; Malhotra H; Raje CI; Raje M
Mol Neurobiol; 2021 Nov; 58(11):5790-5798. PubMed ID: 34406601
[TBL] [Abstract][Full Text] [Related]
5. Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.
Banerjee M; Datta M; Bhattacharyya NP
Int J Biochem Cell Biol; 2017 Jan; 82():1-9. PubMed ID: 27840155
[TBL] [Abstract][Full Text] [Related]
6. LC3-II Tagging and Western Blotting for Monitoring Autophagic Activity in Mammalian Cells.
Streeter A; Menzies FM; Rubinsztein DC
Methods Mol Biol; 2016; 1303():161-70. PubMed ID: 26235065
[TBL] [Abstract][Full Text] [Related]
7. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ; Zhang YY; Fu YH; Zhang H; Li HX; Li QF; Li HL; Tan RK; Jiang CX; Jiang W; Li ZX; Luo C; Lu BX; Dang YJ
Acta Pharmacol Sin; 2021 Oct; 42(10):1556-1566. PubMed ID: 33495516
[TBL] [Abstract][Full Text] [Related]
8. N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.
Chen MZ; Mok SA; Ormsby AR; Muchowski PJ; Hatters DM
J Huntingtons Dis; 2017; 6(1):79-91. PubMed ID: 28339398
[TBL] [Abstract][Full Text] [Related]
9. Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies.
Sarkar S; Ravikumar B; Floto RA; Rubinsztein DC
Cell Death Differ; 2009 Jan; 16(1):46-56. PubMed ID: 18636076
[TBL] [Abstract][Full Text] [Related]
10. Polyglutamine tracts regulate beclin 1-dependent autophagy.
Ashkenazi A; Bento CF; Ricketts T; Vicinanza M; Siddiqi F; Pavel M; Squitieri F; Hardenberg MC; Imarisio S; Menzies FM; Rubinsztein DC
Nature; 2017 May; 545(7652):108-111. PubMed ID: 28445460
[TBL] [Abstract][Full Text] [Related]
11. Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity.
Zhu Y; Li C; Tao X; Brazill JM; Park J; Diaz-Perez Z; Zhai RG
Proc Natl Acad Sci U S A; 2019 Sep; 116(38):19165-19175. PubMed ID: 31484760
[TBL] [Abstract][Full Text] [Related]
12. Autophagic Flux Assessment in Colorectal Cancer Cells.
Lauzier A; Jean S
Methods Mol Biol; 2018; 1765():167-175. PubMed ID: 29589307
[TBL] [Abstract][Full Text] [Related]
13. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.
Li Z; Wang C; Wang Z; Zhu C; Li J; Sha T; Ma L; Gao C; Yang Y; Sun Y; Wang J; Sun X; Lu C; Difiglia M; Mei Y; Ding C; Luo S; Dang Y; Ding Y; Fei Y; Lu B
Nature; 2019 Nov; 575(7781):203-209. PubMed ID: 31666698
[TBL] [Abstract][Full Text] [Related]
14. Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation.
Radwan M; Lilley JD; Ang CS; Reid GE; Hatters DM
PLoS One; 2020; 15(8):e0233247. PubMed ID: 32857759
[TBL] [Abstract][Full Text] [Related]
15. Visualization of prion-like transfer in Huntington's disease models.
Jansen AH; Batenburg KL; Pecho-Vrieseling E; Reits EA
Biochim Biophys Acta Mol Basis Dis; 2017 Mar; 1863(3):793-800. PubMed ID: 28040507
[TBL] [Abstract][Full Text] [Related]
16. Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance.
Martin DDO; Schmidt ME; Nguyen YT; Lazic N; Hayden MR
FASEB J; 2019 Mar; 33(3):3190-3197. PubMed ID: 30423259
[TBL] [Abstract][Full Text] [Related]
17. Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.
Yue F; Li W; Zou J; Chen Q; Xu G; Huang H; Xu Z; Zhang S; Gallinari P; Wang F; McKeehan WL; Liu L
Aging (Albany NY); 2015 Oct; 7(10):839-53. PubMed ID: 26540094
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways.
Moily NS; Ormsby AR; Stojilovic A; Ramdzan YM; Diesch J; Hannan RD; Zajac MS; Hannan AJ; Oshlack A; Hatters DM
Mol Cell Neurosci; 2017 Sep; 83():103-112. PubMed ID: 28743452
[TBL] [Abstract][Full Text] [Related]
19. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
Luo H; Cao L; Liang X; Du A; Peng T; Li H
Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
[TBL] [Abstract][Full Text] [Related]
20. The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy.
Ylä-Anttila P; Gupta S; Masucci MG
Autophagy; 2021 Nov; 17(11):3461-3474. PubMed ID: 33509017
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
