BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 29857136)

  • 1. Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach.
    Paixão P; Bermejo M; Hens B; Tsume Y; Dickens J; Shedden K; Salehi N; Koenigsknecht MJ; Baker JR; Hasler WL; Lionberger R; Fan J; Wysocki J; Wen B; Lee A; Frances A; Amidon GE; Yu A; Benninghoff G; Löbenberg R; Talattof A; Sun D; Amidon GL
    Eur J Pharm Biopharm; 2018 Aug; 129():162-174. PubMed ID: 29857136
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.
    Koenigsknecht MJ; Baker JR; Wen B; Frances A; Zhang H; Yu A; Zhao T; Tsume Y; Pai MP; Bleske BE; Zhang X; Lionberger R; Lee A; Amidon GL; Hasler WL; Sun D
    Mol Pharm; 2017 Dec; 14(12):4295-4304. PubMed ID: 28937221
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools.
    Hens B; Brouwers J; Anneveld B; Corsetti M; Symillides M; Vertzoni M; Reppas C; Turner DB; Augustijns P
    Eur J Pharm Sci; 2014 Oct; 63():233-42. PubMed ID: 25064697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.
    Paixão P; Bermejo M; Hens B; Tsume Y; Dickens J; Shedden K; Salehi N; Koenigsknecht MJ; Baker JR; Hasler WL; Lionberger R; Fan J; Wysocki J; Wen B; Lee A; Frances A; Amidon GE; Yu A; Benninghoff G; Löbenberg R; Talattof A; Sun D; Amidon GL
    Mol Pharm; 2018 Dec; 15(12):5468-5478. PubMed ID: 30417648
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring the impact of real-life dosing conditions on intraluminal and systemic concentrations of atazanavir in parallel with gastric motility recording in healthy subjects.
    Hens B; Masuy I; Deloose E; Mols R; Tack J; Augustijns P
    Eur J Pharm Biopharm; 2020 May; 150():66-76. PubMed ID: 32113916
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantification of gastrointestinal liquid volumes and distribution following a 240 mL dose of water in the fasted state.
    Mudie DM; Murray K; Hoad CL; Pritchard SE; Garnett MC; Amidon GL; Gowland PA; Spiller RC; Amidon GE; Marciani L
    Mol Pharm; 2014 Sep; 11(9):3039-47. PubMed ID: 25115349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of the GastroDuo as an in Vitro Dissolution Tool To Simulate the Gastric Emptying of the Postprandial Stomach.
    Schick P; Sager M; Wegner F; Wiedmann M; Schapperer E; Weitschies W; Koziolek M
    Mol Pharm; 2019 Nov; 16(11):4651-4660. PubMed ID: 31593480
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of surfactants, gastric emptying, and dosage form on supersaturation of dipyridamole in an in vitro model simulating the stomach and duodenum.
    Mitra A; Fadda HM
    Mol Pharm; 2014 Aug; 11(8):2835-44. PubMed ID: 25025699
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir.
    Shono Y; Jantratid E; Dressman JB
    Eur J Pharm Biopharm; 2011 Oct; 79(2):349-56. PubMed ID: 21527341
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Application of the GastroDuo to study the interplay of drug release and gastric emptying in case of immediate release Aspirin formulations.
    Schick P; Sager M; Voelker M; Weitschies W; Koziolek M
    Eur J Pharm Biopharm; 2020 Jun; 151():9-17. PubMed ID: 32268191
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gastrointestinal and Systemic Disposition of Diclofenac under Fasted and Fed State Conditions Supporting the Evaluation of in Vitro Predictive Tools.
    Van Den Abeele J; Schilderink R; Schneider F; Mols R; Minekus M; Weitschies W; Brouwers J; Tack J; Augustijns P
    Mol Pharm; 2017 Dec; 14(12):4220-4232. PubMed ID: 28621952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis.
    Salehi N; Kuminek G; Al-Gousous J; Sperry DC; Greenwood DE; Waltz NM; Amidon GL; Ziff RM; Amidon GE
    Mol Pharm; 2021 Sep; 18(9):3326-3341. PubMed ID: 34428047
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans.
    Shono Y; Jantratid E; Kesisoglou F; Reppas C; Dressman JB
    Eur J Pharm Biopharm; 2010 Sep; 76(1):95-104. PubMed ID: 20576487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of In Vitro Dissolution Testing Methods to Simulate Fed Conditions for Immediate Release Solid Oral Dosage Forms.
    Lex TR; Rodriguez JD; Zhang L; Jiang W; Gao Z
    AAPS J; 2022 Mar; 24(2):40. PubMed ID: 35277760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug dissolution and transit in a heterogenous gastric chyme after fed administration: Semi-mechanistic modeling and simulations for an immediate-release and orodispersible tablets containing a poorly soluble drug.
    Danielak D; Gajda M; Bołtromiuk T; Sulikowska K; Kubiak B; Romański M
    Eur J Pharm Biopharm; 2024 Jul; 200():114341. PubMed ID: 38795785
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gastric Water Emptying under Fed State Clinical Trial Conditions Is as Fast as under Fasted Conditions.
    Grimm M; Scholz E; Koziolek M; Kühn JP; Weitschies W
    Mol Pharm; 2017 Dec; 14(12):4262-4271. PubMed ID: 28930464
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time.
    Yu A; Jackson T; Tsume Y; Koenigsknecht M; Wysocki J; Marciani L; Amidon GL; Frances A; Baker JR; Hasler W; Wen B; Pai A; Sun D
    AAPS J; 2017 Nov; 19(6):1682-1690. PubMed ID: 28980204
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.
    Hens B; Tsume Y; Bermejo M; Paixao P; Koenigsknecht MJ; Baker JR; Hasler WL; Lionberger R; Fan J; Dickens J; Shedden K; Wen B; Wysocki J; Loebenberg R; Lee A; Frances A; Amidon G; Yu A; Benninghoff G; Salehi N; Talattof A; Sun D; Amidon GL
    Mol Pharm; 2017 Dec; 14(12):4281-4294. PubMed ID: 28737409
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans.
    Higaki K; Choe SY; Löbenberg R; Welage LS; Amidon GL
    Eur J Pharm Biopharm; 2008 Sep; 70(1):313-25. PubMed ID: 18434110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of a three compartment in vitro gastrointestinal simulator dissolution apparatus to predict in vivo dissolution.
    Takeuchi S; Tsume Y; Amidon GE; Amidon GL
    J Pharm Sci; 2014 Nov; 103(11):3416-3422. PubMed ID: 25251982
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.