337 related articles for article (PubMed ID: 29859124)
1. Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis.
Shelkovnikova TA; Kukharsky MS; An H; Dimasi P; Alexeeva S; Shabir O; Heath PR; Buchman VL
Mol Neurodegener; 2018 Jun; 13(1):30. PubMed ID: 29859124
[TBL] [Abstract][Full Text] [Related]
2. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.
Nishimoto Y; Nakagawa S; Hirose T; Okano HJ; Takao M; Shibata S; Suyama S; Kuwako K; Imai T; Murayama S; Suzuki N; Okano H
Mol Brain; 2013 Jul; 6():31. PubMed ID: 23835137
[TBL] [Abstract][Full Text] [Related]
3. ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles.
An H; Skelt L; Notaro A; Highley JR; Fox AH; La Bella V; Buchman VL; Shelkovnikova TA
Acta Neuropathol Commun; 2019 Jan; 7(1):7. PubMed ID: 30642400
[TBL] [Abstract][Full Text] [Related]
4. Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
Wang C; Duan Y; Duan G; Wang Q; Zhang K; Deng X; Qian B; Gu J; Ma Z; Zhang S; Guo L; Liu C; Fang Y
Mol Cell; 2020 Aug; 79(3):443-458.e7. PubMed ID: 32649883
[TBL] [Abstract][Full Text] [Related]
5. The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients.
Yamashita T; Kwak S
Brain Res; 2014 Oct; 1584():28-38. PubMed ID: 24355598
[TBL] [Abstract][Full Text] [Related]
6. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.
Highley JR; Kirby J; Jansweijer JA; Webb PS; Hewamadduma CA; Heath PR; Higginbottom A; Raman R; Ferraiuolo L; Cooper-Knock J; McDermott CJ; Wharton SB; Shaw PJ; Ince PG
Neuropathol Appl Neurobiol; 2014 Oct; 40(6):670-85. PubMed ID: 24750229
[TBL] [Abstract][Full Text] [Related]
7. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
[TBL] [Abstract][Full Text] [Related]
8. TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.
Maekawa S; Leigh PN; King A; Jones E; Steele JC; Bodi I; Shaw CE; Hortobagyi T; Al-Sarraj S
Neuropathology; 2009 Dec; 29(6):672-83. PubMed ID: 19496940
[TBL] [Abstract][Full Text] [Related]
9. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.
Turner BJ; Bäumer D; Parkinson NJ; Scaber J; Ansorge O; Talbot K
BMC Neurosci; 2008 Oct; 9():104. PubMed ID: 18957104
[TBL] [Abstract][Full Text] [Related]
10. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Collins M; Riascos D; Kovalik T; An J; Krupa K; Krupa K; Hood BL; Conrads TP; Renton AE; Traynor BJ; Bowser R
Acta Neuropathol; 2012 Nov; 124(5):717-32. PubMed ID: 22993125
[TBL] [Abstract][Full Text] [Related]
11. TDP-43 knockdown in mouse model of ALS leads to dsRNA deposition, gliosis, and neurodegeneration in the spinal cord.
Milstead RA; Link CD; Xu Z; Hoeffer CA
Cereb Cortex; 2023 May; 33(10):5808-5816. PubMed ID: 36443249
[TBL] [Abstract][Full Text] [Related]
12. Compromised paraspeckle formation as a pathogenic factor in FUSopathies.
Shelkovnikova TA; Robinson HK; Troakes C; Ninkina N; Buchman VL
Hum Mol Genet; 2014 May; 23(9):2298-312. PubMed ID: 24334610
[TBL] [Abstract][Full Text] [Related]
13. A robust TDP-43 knock-in mouse model of ALS.
Huang SL; Wu LS; Lee M; Chang CW; Cheng WC; Fang YS; Chen YR; Cheng PL; Shen CJ
Acta Neuropathol Commun; 2020 Jan; 8(1):3. PubMed ID: 31964415
[TBL] [Abstract][Full Text] [Related]
14. [Clinical and pathological spectrum of TDP-43 associated ALS].
Onodera O; Yokoseki A; Tan CF; Ishihara T; Nishiira Y; Toyoshima Y; Kakita A; Nishizawa M; Takahashi H
Rinsho Shinkeigaku; 2010 Nov; 50(11):940-2. PubMed ID: 21921519
[TBL] [Abstract][Full Text] [Related]
15. Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis.
Cacabelos D; Ayala V; Granado-Serrano AB; Jové M; Torres P; Boada J; Cabré R; Ramírez-Núñez O; Gonzalo H; Soler-Cantero A; Serrano JC; Bellmunt MJ; Romero MP; Motilva MJ; Nonaka T; Hasegawa M; Ferrer I; Pamplona R; Portero-Otín M
Neurobiol Dis; 2016 Apr; 88():148-60. PubMed ID: 26805387
[TBL] [Abstract][Full Text] [Related]
16. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
[TBL] [Abstract][Full Text] [Related]
17. Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology.
Ince PG; Highley JR; Kirby J; Wharton SB; Takahashi H; Strong MJ; Shaw PJ
Acta Neuropathol; 2011 Dec; 122(6):657-71. PubMed ID: 22105541
[TBL] [Abstract][Full Text] [Related]
18. Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam.
Geser F; Winton MJ; Kwong LK; Xu Y; Xie SX; Igaz LM; Garruto RM; Perl DP; Galasko D; Lee VM; Trojanowski JQ
Acta Neuropathol; 2008 Jan; 115(1):133-45. PubMed ID: 17713769
[TBL] [Abstract][Full Text] [Related]
19. GPNMB ameliorates mutant TDP-43-induced motor neuron cell death.
Nagahara Y; Shimazawa M; Ohuchi K; Ito J; Takahashi H; Tsuruma K; Kakita A; Hara H
J Neurosci Res; 2017 Aug; 95(8):1647-1665. PubMed ID: 27935101
[TBL] [Abstract][Full Text] [Related]
20. Spinal cord extracts of amyotrophic lateral sclerosis spread TDP-43 pathology in cerebral organoids.
Tamaki Y; Ross JP; Alipour P; Castonguay CÉ; Li B; Catoire H; Rochefort D; Urushitani M; Takahashi R; Sonnen JA; Stifani S; Dion PA; Rouleau GA
PLoS Genet; 2023 Feb; 19(2):e1010606. PubMed ID: 36745687
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
