426 related articles for article (PubMed ID: 29859519)
1. [Bioanalysis in the development of antibody-drug conjugates].
Li XL; Chen XY; Zhong DF
Yao Xue Xue Bao; 2016 Apr; 51(4):517-28. PubMed ID: 29859519
[TBL] [Abstract][Full Text] [Related]
2. Bioanalysis of antibody-drug conjugates: American Association of Pharmaceutical Scientists Antibody-Drug Conjugate Working Group position paper.
Gorovits B; Alley SC; Bilic S; Booth B; Kaur S; Oldfield P; Purushothama S; Rao C; Shord S; Siguenza P
Bioanalysis; 2013 May; 5(9):997-1006. PubMed ID: 23641692
[TBL] [Abstract][Full Text] [Related]
3. Current Analytical Strategies for Antibody-Drug Conjugates in Biomatrices.
Qin Q; Gong L
Molecules; 2022 Sep; 27(19):. PubMed ID: 36234836
[TBL] [Abstract][Full Text] [Related]
4. Characterization of intact antibody-drug conjugates from plasma/serum in vivo by affinity capture capillary liquid chromatography-mass spectrometry.
Xu K; Liu L; Saad OM; Baudys J; Williams L; Leipold D; Shen B; Raab H; Junutula JR; Kim A; Kaur S
Anal Biochem; 2011 May; 412(1):56-66. PubMed ID: 21216214
[TBL] [Abstract][Full Text] [Related]
5. Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates.
Sun X; Ponte JF; Yoder NC; Laleau R; Coccia J; Lanieri L; Qiu Q; Wu R; Hong E; Bogalhas M; Wang L; Dong L; Setiady Y; Maloney EK; Ab O; Zhang X; Pinkas J; Keating TA; Chari R; Erickson HK; Lambert JM
Bioconjug Chem; 2017 May; 28(5):1371-1381. PubMed ID: 28388844
[TBL] [Abstract][Full Text] [Related]
6. Practical considerations for the pharmacokinetic and immunogenic assessment of antibody-drug conjugates.
Sauerborn M; van Dongen W
BioDrugs; 2014 Aug; 28(4):383-91. PubMed ID: 24842227
[TBL] [Abstract][Full Text] [Related]
7. Antibody-drug conjugate bioanalysis using LB-LC-MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays.
Wang J; Gu H; Liu A; Kozhich A; Rangan V; Myler H; Luo L; Wong R; Sun H; Wang B; Vezina HE; Deshpande S; Zhang Y; Yang Z; Olah TV; Aubry AF; Arnold ME; Pillutla R; DeSilva B
Bioanalysis; 2016 Jul; 8(13):1383-401. PubMed ID: 27277879
[TBL] [Abstract][Full Text] [Related]
8. Considerations for the nonclinical safety evaluation of antibody drug conjugates for oncology.
Roberts SA; Andrews PA; Blanset D; Flagella KM; Gorovits B; Lynch CM; Martin PL; Kramer-Stickland K; Thibault S; Warner G
Regul Toxicol Pharmacol; 2013 Dec; 67(3):382-91. PubMed ID: 24012707
[TBL] [Abstract][Full Text] [Related]
9. Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs.
Behrens CR; Ha EH; Chinn LL; Bowers S; Probst G; Fitch-Bruhns M; Monteon J; Valdiosera A; Bermudez A; Liao-Chan S; Wong T; Melnick J; Theunissen JW; Flory MR; Houser D; Venstrom K; Levashova Z; Sauer P; Migone TS; van der Horst EH; Halcomb RL; Jackson DY
Mol Pharm; 2015 Nov; 12(11):3986-98. PubMed ID: 26393951
[TBL] [Abstract][Full Text] [Related]
10. Bioanalytical assay strategies for the development of antibody-drug conjugate biotherapeutics.
Kaur S; Xu K; Saad OM; Dere RC; Carrasco-Triguero M
Bioanalysis; 2013 Jan; 5(2):201-26. PubMed ID: 23330562
[TBL] [Abstract][Full Text] [Related]
11. Calculated conjugated payload from immunoassay and LC-MS intact protein analysis measurements of antibody-drug conjugate.
Rago B; Clark T; King L; Zhang J; Tumey LN; Li F; Barletta F; Wei C; Leal M; Hansel S; Han X
Bioanalysis; 2016 Nov; 8(21):2205-2217. PubMed ID: 27682846
[TBL] [Abstract][Full Text] [Related]
12. Development and Translational Application of an Integrated, Mechanistic Model of Antibody-Drug Conjugate Pharmacokinetics.
Sukumaran S; Zhang C; Leipold DD; Saad OM; Xu K; Gadkar K; Samineni D; Wang B; Milojic-Blair M; Carrasco-Triguero M; Rubinfeld B; Fielder P; Lin K; Ramanujan S
AAPS J; 2017 Jan; 19(1):130-140. PubMed ID: 27679517
[TBL] [Abstract][Full Text] [Related]
13. Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC-MS/MS approach: Assay development, validation, and a case study.
Liu A; Kozhich A; Passmore D; Gu H; Wong R; Zambito F; Rangan VS; Myler H; Aubry AF; Arnold ME; Wang J
J Chromatogr B Analyt Technol Biomed Life Sci; 2015 Oct; 1002():54-62. PubMed ID: 26310897
[TBL] [Abstract][Full Text] [Related]
14. A new anti-human Fc method to capture and analyze ADCs for characterization of drug distribution and the drug-to-antibody ratio in serum from pre-clinical species.
Excoffier M; Janin-Bussat MC; Beau-Larvor C; Troncy L; Corvaia N; Beck A; Klinguer-Hamour C
J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1032():149-154. PubMed ID: 27267073
[TBL] [Abstract][Full Text] [Related]
15. Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.
Debaene F; Boeuf A; Wagner-Rousset E; Colas O; Ayoub D; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
Anal Chem; 2014 Nov; 86(21):10674-83. PubMed ID: 25270580
[TBL] [Abstract][Full Text] [Related]
16. Immunoprecipitation middle-up LC-MS for in vivo drug-to-antibody ratio determination for antibody-drug conjugates.
Davis JA; Kagan M; Read J; Walles M; Hatsis P
Bioanalysis; 2017 Oct; 9(20):1535-1549. PubMed ID: 29072490
[TBL] [Abstract][Full Text] [Related]
17. Current methods for the synthesis of homogeneous antibody-drug conjugates.
Sochaj AM; Świderska KW; Otlewski J
Biotechnol Adv; 2015 Nov; 33(6 Pt 1):775-84. PubMed ID: 25981886
[TBL] [Abstract][Full Text] [Related]
18. In vivo testing of drug-linker stability.
Abecassis PY; Amara C
Methods Mol Biol; 2013; 1045():101-16. PubMed ID: 23913143
[TBL] [Abstract][Full Text] [Related]
19. Characterization of the drug-to-antibody ratio distribution for antibody-drug conjugates in plasma/serum.
Xu K; Liu L; Dere R; Mai E; Erickson R; Hendricks A; Lin K; Junutula JR; Kaur S
Bioanalysis; 2013 May; 5(9):1057-71. PubMed ID: 23641696
[TBL] [Abstract][Full Text] [Related]
20. Characterization of antibody-drug conjugates by mass spectrometry: advances and future trends.
Huang RY; Chen G
Drug Discov Today; 2016 May; 21(5):850-5. PubMed ID: 27080148
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]