BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 29860433)

  • 1. Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
    Tapias V; Jainuddin S; Ahuja M; Stack C; Elipenahli C; Vignisse J; Gerges M; Starkova N; Xu H; Starkov AA; Bettendorff L; Hushpulian DM; Smirnova NA; Gazaryan IG; Kaidery NA; Wakade S; Calingasan NY; Thomas B; Gibson GE; Dumont M; Beal MF
    Hum Mol Genet; 2018 Aug; 27(16):2874-2892. PubMed ID: 29860433
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.
    Stack C; Jainuddin S; Elipenahli C; Gerges M; Starkova N; Starkov AA; Jové M; Portero-Otin M; Launay N; Pujol A; Kaidery NA; Thomas B; Tampellini D; Beal MF; Dumont M
    Hum Mol Genet; 2014 Jul; 23(14):3716-32. PubMed ID: 24556215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nrf2 Suppresses Oxidative Stress and Inflammation in
    Uruno A; Matsumaru D; Ryoke R; Saito R; Kadoguchi S; Saigusa D; Saito T; Saido TC; Kawashima R; Yamamoto M
    Mol Cell Biol; 2020 Feb; 40(6):. PubMed ID: 31932477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
    Li L; Li WJ; Zheng XR; Liu QL; Du Q; Lai YJ; Liu SQ
    Mol Med; 2022 Jan; 28(1):11. PubMed ID: 35093024
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.
    Pan X; Gong N; Zhao J; Yu Z; Gu F; Chen J; Sun X; Zhao L; Yu M; Xu Z; Dong W; Qin Y; Fei G; Zhong C; Xu TL
    Brain; 2010 May; 133(Pt 5):1342-51. PubMed ID: 20385653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
    Ren P; Chen J; Li B; Zhang M; Yang B; Guo X; Chen Z; Cheng H; Wang P; Wang S; Wang N; Zhang G; Wu X; Ma D; Guan D; Zhao R
    Oxid Med Cell Longev; 2020; 2020():3050971. PubMed ID: 32454936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.
    Rosenmann H; Grigoriadis N; Eldar-Levy H; Avital A; Rozenstein L; Touloumi O; Behar L; Ben-Hur T; Avraham Y; Berry E; Segal M; Ginzburg I; Abramsky O
    Exp Neurol; 2008 Jul; 212(1):71-84. PubMed ID: 18490011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
    Cazzaro S; Woo JA; Wang X; Liu T; Rego S; Kee TR; Koh Y; Vázquez-Rosa E; Pieper AA; Kang DE
    Proc Natl Acad Sci U S A; 2023 Jul; 120(30):e2217128120. PubMed ID: 37463212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease.
    Sun Y; Xu L; Zheng D; Wang J; Liu G; Mo Z; Liu C; Zhang W; Yu J; Xing C; He L; Zhuang C
    Redox Biol; 2023 Aug; 64():102793. PubMed ID: 37385075
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset.
    Dionísio PA; Amaral JD; Ribeiro MF; Lo AC; D'Hooge R; Rodrigues CM
    Neurobiol Aging; 2015 Jan; 36(1):228-40. PubMed ID: 25443293
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutic Approaches to Alzheimer's Disease Through Modulation of NRF2.
    Bahn G; Jo DG
    Neuromolecular Med; 2019 Mar; 21(1):1-11. PubMed ID: 30617737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Artemether Activation of AMPK/GSK3
    Li S; Zhao X; Lazarovici P; Zheng W
    Oxid Med Cell Longev; 2019; 2019():1862437. PubMed ID: 31871541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line.
    Cui B; Zhang S; Wang Y; Guo Y
    Biomed Pharmacother; 2019 Jan; 109():112-119. PubMed ID: 30396067
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selenepezil, a Selenium-Containing Compound, Exerts Neuroprotective Effect via Modulation of the Keap1-Nrf2-ARE Pathway and Attenuates Aβ-Induced Cognitive Impairment in Vivo.
    Yan J; Pang Y; Zhuang J; Lin H; Zhang Q; Han L; Ke P; Zhuang J; Huang X
    ACS Chem Neurosci; 2019 Jun; 10(6):2903-2914. PubMed ID: 31035749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P301S-hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau-induced synaptic toxicities.
    Xie JZ; Zhang Y; Li SH; Wei H; Yu HL; Zhou QZ; Wei LY; Ke D; Wang Q; Yang Y; Wang JZ
    Clin Transl Med; 2022 Aug; 12(8):e1003. PubMed ID: 35917404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice.
    Zhang YH; Wang DW; Xu SF; Zhang S; Fan YG; Yang YY; Guo SQ; Wang S; Guo T; Wang ZY; Guo C
    Redox Biol; 2018 Apr; 14():535-548. PubMed ID: 29126071
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy.
    Cuadrado A; Kügler S; Lastres-Becker I
    Redox Biol; 2018 Apr; 14():522-534. PubMed ID: 29121589
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
    Jiwaji Z; Tiwari SS; Avilés-Reyes RX; Hooley M; Hampton D; Torvell M; Johnson DA; McQueen J; Baxter P; Sabari-Sankar K; Qiu J; He X; Fowler J; Febery J; Gregory J; Rose J; Tulloch J; Loan J; Story D; McDade K; Smith AM; Greer P; Ball M; Kind PC; Matthews PM; Smith C; Dando O; Spires-Jones TL; Johnson JA; Chandran S; Hardingham GE
    Nat Commun; 2022 Jan; 13(1):135. PubMed ID: 35013236
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in
    Bian Y; Chen Y; Wang X; Cui G; Ung COL; Lu JH; Cong W; Tang B; Lee SM
    J Adv Res; 2021 Dec; 34():1-12. PubMed ID: 35024177
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance.
    Jiang T; Yu JT; Zhu XC; Zhang QQ; Cao L; Wang HF; Tan MS; Gao Q; Qin H; Zhang YD; Tan L
    Neuropharmacology; 2014 Oct; 85():121-30. PubMed ID: 24880087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.