311 related articles for article (PubMed ID: 29864685)
1. Benzimidazole scaffold based hybrid molecules for various inflammatory targets: Synthesis and evaluation.
Kaur G; Silakari O
Bioorg Chem; 2018 Oct; 80():24-35. PubMed ID: 29864685
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
3. Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition.
Ghanim AM; Rezq S; Ibrahim TS; Romero DG; Kothayer H
Eur J Med Chem; 2021 Jul; 219():113457. PubMed ID: 33892270
[TBL] [Abstract][Full Text] [Related]
4. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
El-Miligy MMM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SAM
Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
Abdelgawad MA; Labib MB; Ali WAM; Kamel G; Azouz AA; El-Nahass ES
Bioorg Chem; 2018 Aug; 78():103-114. PubMed ID: 29550530
[TBL] [Abstract][Full Text] [Related]
6. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
[TBL] [Abstract][Full Text] [Related]
7. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
Maghraby MT; Abou-Ghadir OMF; Abdel-Moty SG; Ali AY; Salem OIA
Bioorg Med Chem; 2020 Apr; 28(7):115403. PubMed ID: 32127262
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
Huang Y; Zhang B; Li J; Liu H; Zhang Y; Yang Z; Liu W
Eur J Med Chem; 2019 Oct; 180():41-50. PubMed ID: 31299586
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
Omar YM; Abdu-Allah HHM; Abdel-Moty SG
Bioorg Chem; 2018 Oct; 80():461-471. PubMed ID: 29986191
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
Gedawy EM; Kassab AE; El Kerdawy AM
Eur J Med Chem; 2020 Mar; 189():112066. PubMed ID: 31982653
[TBL] [Abstract][Full Text] [Related]
13. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
El-Miligy MM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SA
Future Med Chem; 2017 Apr; 9(5):443-468. PubMed ID: 28362117
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.
Abdelrahman MH; Youssif BGM; Abdelgawad MA; Abdelazeem AH; Ibrahim HM; Moustafa AEGA; Treamblu L; Bukhari SNA
Eur J Med Chem; 2017 Feb; 127():972-985. PubMed ID: 27837994
[TBL] [Abstract][Full Text] [Related]
15. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
Moussa G; Alaaeddine R; Alaeddine LM; Nassra R; Belal ASF; Ismail A; El-Yazbi AF; Abdel-Ghany YS; Hazzaa A
Eur J Med Chem; 2018 Jan; 144():635-650. PubMed ID: 29289887
[TBL] [Abstract][Full Text] [Related]
16. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
Abd El Razik HA; Badr MH; Atta AH; Mouneir SM; Abu-Serie MM
Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
[TBL] [Abstract][Full Text] [Related]
17. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
Abdelgawad MA; Labib MB; Abdel-Latif M
Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
Chaaban I; Rizk OH; Ibrahim TM; Henen SS; El-Khawass EM; Bayad AE; El-Ashmawy IM; Nematalla HA
Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
[TBL] [Abstract][Full Text] [Related]
19. Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes.
El-Miligy MMM; Al-Kubeisi AK; El-Zemity SR; Nassra RA; Abu-Serie MM; Hazzaa AA
Bioorg Chem; 2021 Oct; 115():105171. PubMed ID: 34303896
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
Özadalı K; Özkanlı F; Jain S; Rao PP; Velázquez-Martínez CA
Bioorg Med Chem; 2012 May; 20(9):2912-22. PubMed ID: 22475926
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]