BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 29869097)

  • 1. Patched-2 functions to limit Patched-1 deficient skin cancer growth.
    Veenstra VL; Dingjan I; Waasdorp C; Damhofer H; van der Wal AC; van Laarhoven HW; Medema JP; Bijlsma MF
    Cell Oncol (Dordr); 2018 Aug; 41(4):427-437. PubMed ID: 29869097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.
    Fleet AJ; Hamel PA
    J Biol Chem; 2018 Oct; 293(43):16583-16595. PubMed ID: 30166346
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Patched1 and Patched2 inhibit Smoothened non-cell autonomously.
    Roberts B; Casillas C; Alfaro AC; Jägers C; Roelink H
    Elife; 2016 Aug; 5():. PubMed ID: 27552050
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.
    Zhulyn O; Nieuwenhuis E; Liu YC; Angers S; Hui CC
    Dev Biol; 2015 Jan; 397(2):191-202. PubMed ID: 25448692
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alternative activation of hedgehog pathway induced by ultraviolet B radiation: preliminary study.
    Lesiak A; Sobolewska-Sztychny D; Bednarski IA; Wódz K; Sobjanek M; Woźniacka A; Narbutt J
    Clin Exp Dermatol; 2018 Jul; 43(5):518-524. PubMed ID: 29424103
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression profile of sonic hedgehog signaling-related molecules in basal cell carcinoma.
    Kim HS; Kim YS; Lee C; Shin MS; Kim JW; Jang BG
    PLoS One; 2019; 14(11):e0225511. PubMed ID: 31756206
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct roles of PTCH2 splice variants in Hedgehog signalling.
    Rahnama F; Toftgård R; Zaphiropoulos PG
    Biochem J; 2004 Mar; 378(Pt 2):325-34. PubMed ID: 14613484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ptch2 mediates the Shh response in Ptch1-/- cells.
    Alfaro AC; Roberts B; Kwong L; Bijlsma MF; Roelink H
    Development; 2014 Sep; 141(17):3331-9. PubMed ID: 25085974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
    Kim Y; Lee J; Seppala M; Cobourne MT; Kim SH
    Nat Commun; 2020 Apr; 11(1):1994. PubMed ID: 32332736
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
    Holtz AM; Peterson KA; Nishi Y; Morin S; Song JY; Charron F; McMahon AP; Allen BL
    Development; 2013 Aug; 140(16):3423-34. PubMed ID: 23900540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PTCH2, a novel human patched gene, undergoing alternative splicing and up-regulated in basal cell carcinomas.
    Zaphiropoulos PG; Undén AB; Rahnama F; Hollingsworth RE; Toftgård R
    Cancer Res; 1999 Feb; 59(4):787-92. PubMed ID: 10029063
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.
    Villani RM; Adolphe C; Palmer J; Waters MJ; Wainwright BJ
    Cancer Prev Res (Phila); 2010 Oct; 3(10):1222-34. PubMed ID: 20858761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient.
    Adolphe C; Junker JP; Lyubimova A; van Oudenaarden A; Wainwright B
    J Invest Dermatol; 2017 Jan; 137(1):179-186. PubMed ID: 27498049
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of two patched receptors for the vertebrate hedgehog protein family.
    Carpenter D; Stone DM; Brush J; Ryan A; Armanini M; Frantz G; Rosenthal A; de Sauvage FJ
    Proc Natl Acad Sci U S A; 1998 Nov; 95(23):13630-4. PubMed ID: 9811851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Novel Mechanism for Activation of GLI1 by Nuclear SMO That Escapes Anti-SMO Inhibitors.
    Rahman MM; Hazan A; Selway JL; Herath DS; Harwood CA; Pirzado MS; Atkar R; Kelsell DP; Linton KJ; Philpott MP; Neill GW
    Cancer Res; 2018 May; 78(10):2577-2588. PubMed ID: 29463581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Patched2 modulates tumorigenesis in patched1 heterozygous mice.
    Lee Y; Miller HL; Russell HR; Boyd K; Curran T; McKinnon PJ
    Cancer Res; 2006 Jul; 66(14):6964-71. PubMed ID: 16849540
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice.
    Mancuso M; Pazzaglia S; Tanori M; Hahn H; Merola P; Rebessi S; Atkinson MJ; Di Majo V; Covelli V; Saran A
    Cancer Res; 2004 Feb; 64(3):934-41. PubMed ID: 14871823
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Immunohistochemical evaluation of Sonic Hedgehog signaling pathway proteins (Shh, Ptch1, Ptch2, Smo, Gli1, Gli2, and Gli3) in sporadic and syndromic odontogenic keratocysts.
    Hoyos Cadavid AM; Kaminagakura E; Rodrigues MFSD; Pinto CAL; Teshima THN; Alves FA
    Clin Oral Investig; 2019 Jan; 23(1):153-159. PubMed ID: 29564556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas.
    Albert B; Hahn H
    Adv Exp Med Biol; 2014; 810():329-41. PubMed ID: 25207374
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation.
    Adolphe C; Nieuwenhuis E; Villani R; Li ZJ; Kaur P; Hui CC; Wainwright BJ
    J Invest Dermatol; 2014 Jul; 134(7):1981-1990. PubMed ID: 24492243
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.