These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 2987041)

  • 1. Murine mammary FM3A carcinoma cells transformed with the herpes simplex virus type 1 thymidine kinase gene are highly sensitive to the growth-inhibitory properties of (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
    Balzarini J; de Clercq E; Ayusawa D; Seno T
    FEBS Lett; 1985 Jun; 185(1):95-100. PubMed ID: 2987041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Highly selective cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine derivatives for murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Seno T
    Mol Pharmacol; 1985 Dec; 28(6):581-7. PubMed ID: 3001499
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Shimizu K; Seno T
    Mol Pharmacol; 1987 Sep; 32(3):410-6. PubMed ID: 2823092
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective inhibition of the proliferation of herpes simplex virus type 1 thymidine kinase gene-transformed murine mammary FM3A carcinoma cells by (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
    Balzarini J; De Clercq E; Ayusawa D; Shimizu K; Seno T
    Nucleic Acids Symp Ser; 1985; (16):283-6. PubMed ID: 3003708
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2.
    Balzarini J; Bohman C; De Clercq E
    J Biol Chem; 1993 Mar; 268(9):6332-7. PubMed ID: 8384209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
    Balzarini J; De Clercq E; Verbruggen A; Crumpacker C; Ayusawa D; Seno T
    Anticancer Res; 1986; 6(5):1077-84. PubMed ID: 2432829
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells.
    Balzarini J; Bohman C; Walker RT; de Clercq E
    Mol Pharmacol; 1994 Jun; 45(6):1253-8. PubMed ID: 8022417
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selection of HSV-1 TK gene-transfected murine mammary carcinoma cells resistant to (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and ganciclovir (GCV).
    Degrève B; De Clercq E; Balzarini J
    Gene Ther; 2000 Sep; 7(18):1543-52. PubMed ID: 11021592
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active: interaction of the (+)- and (-)-enantiomers of C-IDU and C-BVDU with the thymidine kinase of herpes simplex virus type 1.
    Balzarini J; De Clercq E; Baumgartner H; Bodenteich M; Griengl H
    Mol Pharmacol; 1990 Mar; 37(3):395-401. PubMed ID: 2156153
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel (E)-5-(2-iodovinyl)-2'-deoxyuridine derivatives as potential cytostatic agents against herpes simplex virus thymidine kinase gene transfected tumors.
    Balzarini J; Morin KW; Knaus EE; Wiebe LI; De Clercq E
    Gene Ther; 1995 Jul; 2(5):317-22. PubMed ID: 7671107
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Establishment of mutant murine mammary carcinoma FM3A cell strains transformed with the herpes simplex virus type 2 thymidine kinase gene.
    Shimizu K; Ren L; Ayusawa D; Seno T; Balzarini J; De Clercq E
    Cell Struct Funct; 1986 Sep; 11(3):295-301. PubMed ID: 3021345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine on the proliferation of herpes simplex virus type 1-transformed and thymidine kinase-deficient mouse cells.
    Bubley G; Crumpacker C; De Clercq E; Schnipper L
    Virology; 1983 Sep; 129(2):490-2. PubMed ID: 6312685
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds on herpes simplex virus (HSV)-infected cells and HSV thymidine kinase gene-transformed cells.
    Balzarini J; De Clercq E
    Methods Find Exp Clin Pharmacol; 1989 Jun; 11(6):379-89. PubMed ID: 2545982
    [No Abstract]   [Full Text] [Related]  

  • 14. Selective antiherpetic activity of carbocyclic analogues of (E)-5-(2-halogenovinyl)-2'-deoxyuridines: dependence on specific phosphorylation by viral thymidine kinase.
    De Clercq E; Balzarini J; Bernaerts R; Herdewijn P; Verbruggen A
    Biochem Biophys Res Commun; 1985 Jan; 126(1):397-403. PubMed ID: 2982373
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase.
    Grignet-Debrus C; Cool V; Baudson N; Degrève B; Balzarini J; De Leval L; Debrus S; Velu T; Calberg-Bacq CM
    Cancer Gene Ther; 2000 Feb; 7(2):215-23. PubMed ID: 10770629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Herpes simplex virus type 1 that exhibits herpes simplex virus type 2 sensitivity to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Docherty JJ; Dobson AT; Trimble JJ; Jennings BA
    Intervirology; 1991; 32(5):308-15. PubMed ID: 1657822
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selection of L cell sublines resistant to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Shiraki K; Vonka V; De Clercq E; Rapp F
    Intervirology; 1991; 32(4):228-33. PubMed ID: 1650764
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishment of mutant FM3A murine mammary carcinoma cell strains transformed with the herpes simplex virus type 1 thymidine kinase gene.
    Ayusawa D; Shimizu K; Seno T; Balzarini J; De Clercq E
    Jpn J Cancer Res; 1985 Oct; 76(10):984-8. PubMed ID: 3001011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. (E)-5-(2-bromovinyl)-2'-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase--expressing cells.
    Hamel W; Zirkel D; Mehdorn HM; Westphal M; Israel MA
    Cancer Gene Ther; 2001 May; 8(5):388-96. PubMed ID: 11477459
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential metabolism of (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVDU) by equine herpesvirus type 1- and herpes simplex virus-infected cells.
    Kit S; Ichimura H; De Clercq E
    Antiviral Res; 1987 Aug; 8(1):41-51. PubMed ID: 2825591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.