BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 29875165)

  • 1. Critical role for the Tsc1-mTORC1 pathway in β-cell mass in Pdx1-deficient mice.
    Sun J; Mao L; Yang H; Ren D
    J Endocrinol; 2018 Aug; 238(2):151-163. PubMed ID: 29875165
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency.
    Ren D; Sun J; Wang C; Ye H; Mao L; Cheng EH; Bell GI; Polonsky KS
    Diabetes; 2014 Aug; 63(8):2744-50. PubMed ID: 24658302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes.
    Fujimoto K; Ford EL; Tran H; Wice BM; Crosby SD; Dorn GW; Polonsky KS
    J Clin Invest; 2010 Nov; 120(11):4031-9. PubMed ID: 20978346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pancreatic and duodenal homeobox-1 (PDX1) contributes to β-cell mass expansion and proliferation induced by Akt/PKB pathway.
    Jara MA; Werneck-De-Castro JP; Lubaczeuski C; Johnson JD; Bernal-Mizrachi E
    Islets; 2020 Mar; 12(2):32-40. PubMed ID: 32876522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pancreatic β-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak.
    Sun J; Mao LQ; Polonsky KS; Ren DC
    J Biol Chem; 2016 Jun; 291(26):13529-34. PubMed ID: 27137932
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency.
    Fujimoto K; Chen Y; Polonsky KS; Dorn GW
    Proc Natl Acad Sci U S A; 2010 Jun; 107(22):10214-9. PubMed ID: 20479245
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation.
    Fujimoto K; Hanson PT; Tran H; Ford EL; Han Z; Johnson JD; Schmidt RE; Green KG; Wice BM; Polonsky KS
    J Biol Chem; 2009 Oct; 284(40):27664-73. PubMed ID: 19654319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative regulation of c-Myc transcription by pancreas duodenum homeobox-1.
    Chen L; Yan HX; Chen J; Yang W; Liu Q; Zhai B; Cao HF; Liu SQ; Wu MC; Wang HY
    Endocrinology; 2007 May; 148(5):2168-80. PubMed ID: 17317781
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TSC1 deletion in fibroblasts alleviates lipopolysaccharide-induced acute kidney injury.
    Shen J; Cui ZK; Yao F; Li K; Zhang Y; Chen Z; Zhou Y; Xu S; Zhang Y; Jiang W; Zhang H; Tan K; Liu A; Bai X
    Clin Sci (Lond); 2018 Oct; 132(19):2087-2101. PubMed ID: 30185506
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
    Kohara K; Obata A; Kimura T; Shimoda M; Moriuchi S; Okauchi S; Hirukawa H; Mune T; Kaku K; Kaneto H
    Endocr J; 2019 Jan; 66(1):43-50. PubMed ID: 30333365
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress.
    Sachdeva MM; Claiborn KC; Khoo C; Yang J; Groff DN; Mirmira RG; Stoffers DA
    Proc Natl Acad Sci U S A; 2009 Nov; 106(45):19090-5. PubMed ID: 19855005
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A PDX1-ATF transcriptional complex governs β cell survival during stress.
    Juliana CA; Yang J; Cannon CE; Good AL; Haemmerle MW; Stoffers DA
    Mol Metab; 2018 Nov; 17():39-48. PubMed ID: 30174228
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GPR120 protects lipotoxicity-induced pancreatic β-cell dysfunction through regulation of PDX1 expression and inhibition of islet inflammation.
    Wang Y; Xie T; Zhang D; Leung PS
    Clin Sci (Lond); 2019 Jan; 133(1):101-116. PubMed ID: 30523046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.
    An R; da Silva Xavier G; Semplici F; Vakhshouri S; Hao HX; Rutter J; Pagano MA; Meggio F; Pinna LA; Rutter GA
    Biochem Biophys Res Commun; 2010 Aug; 399(2):155-61. PubMed ID: 20637728
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development.
    Elghazi L; Blandino-Rosano M; Alejandro E; Cras-Méneur C; Bernal-Mizrachi E
    Mol Metab; 2017 Jun; 6(6):560-573. PubMed ID: 28580286
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATF5 regulates β-cell survival during stress.
    Juliana CA; Yang J; Rozo AV; Good A; Groff DN; Wang SZ; Green MR; Stoffers DA
    Proc Natl Acad Sci U S A; 2017 Feb; 114(6):1341-1346. PubMed ID: 28115692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
    Haji N; Riebe I; Aguilar-Valles A; Artinian J; Laplante I; Lacaille JC
    Mol Autism; 2020 May; 11(1):29. PubMed ID: 32375878
    [TBL] [Abstract][Full Text] [Related]  

  • 18. mTORC1 signaling and regulation of pancreatic β-cell mass.
    Blandino-Rosano M; Chen AY; Scheys JO; Alejandro EU; Gould AP; Taranukha T; Elghazi L; Cras-Méneur C; Bernal-Mizrachi E
    Cell Cycle; 2012 May; 11(10):1892-902. PubMed ID: 22544327
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TAZ promotes PDX1-mediated insulinogenesis.
    Jeong MG; Kim HK; Lee G; Won HY; Yoon DH; Hwang ES
    Cell Mol Life Sci; 2022 Mar; 79(3):186. PubMed ID: 35279781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.
    Maganti AV; Maier B; Tersey SA; Sampley ML; Mosley AL; Özcan S; Pachaiyappan B; Woster PM; Hunter CS; Stein R; Mirmira RG
    J Biol Chem; 2015 Apr; 290(15):9812-22. PubMed ID: 25713082
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.