BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 29879455)

  • 1. hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α
    Segeritz CP; Rashid ST; de Brito MC; Serra MP; Ordonez A; Morell CM; Kaserman JE; Madrigal P; Hannan NRF; Gatto L; Tan L; Wilson AA; Lilley K; Marciniak SJ; Gooptu B; Lomas DA; Vallier L
    J Hepatol; 2018 Oct; 69(4):851-860. PubMed ID: 29879455
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency.
    Ordóñez A; Snapp EL; Tan L; Miranda E; Marciniak SJ; Lomas DA
    Hepatology; 2013 May; 57(5):2049-60. PubMed ID: 23197448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. α1-Antitrypsin deficiency.
    Greene CM; Marciniak SJ; Teckman J; Ferrarotti I; Brantly ML; Lomas DA; Stoller JK; McElvaney NG
    Nat Rev Dis Primers; 2016 Jul; 2():16051. PubMed ID: 27465791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency.
    Yip E; Giousoh A; Fung C; Wilding B; Prakash MD; Williams C; Verkade H; Bryson-Richardson RJ; Bird PI
    Biol Chem; 2019 Nov; 400(12):1603-1616. PubMed ID: 31091192
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency.
    Lawless MW; Greene CM; Mulgrew A; Taggart CC; O'Neill SJ; McElvaney NG
    J Immunol; 2004 May; 172(9):5722-6. PubMed ID: 15100318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
    Khodayari N; Wang RL; Oshins R; Lu Y; Millett M; Aranyos AM; Mostofizadeh S; Scindia Y; Flagg TO; Brantly M
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells.
    Yusa K; Rashid ST; Strick-Marchand H; Varela I; Liu PQ; Paschon DE; Miranda E; Ordóñez A; Hannan NR; Rouhani FJ; Darche S; Alexander G; Marciniak SJ; Fusaki N; Hasegawa M; Holmes MC; Di Santo JP; Lomas DA; Bradley A; Vallier L
    Nature; 2011 Oct; 478(7369):391-4. PubMed ID: 21993621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α
    Khodayari N; Oshins R; Alli AA; Tuna KM; Holliday LS; Krotova K; Brantly M
    J Biol Chem; 2019 Apr; 294(16):6240-6252. PubMed ID: 30833329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The molecular and cellular pathology of α₁-antitrypsin deficiency.
    Gooptu B; Dickens JA; Lomas DA
    Trends Mol Med; 2014 Feb; 20(2):116-27. PubMed ID: 24374162
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.
    Tafaleng EN; Chakraborty S; Han B; Hale P; Wu W; Soto-Gutierrez A; Feghali-Bostwick CA; Wilson AA; Kotton DN; Nagaya M; Strom SC; Roy-Chowdhury J; Stolz DB; Perlmutter DH; Fox IJ
    Hepatology; 2015 Jul; 62(1):147-57. PubMed ID: 25690322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The selective advantage of alpha1-antitrypsin deficiency.
    Lomas DA
    Am J Respir Crit Care Med; 2006 May; 173(10):1072-7. PubMed ID: 16439713
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatocyte proteomes reveal the role of protein disulfide isomerase 4 in alpha 1-antitrypsin deficiency.
    Karatas E; Raymond AA; Leon C; Dupuy JW; Di-Tommaso S; Senant N; Collardeau-Frachon S; Ruiz M; Lachaux A; Saltel F; Bouchecareilh M
    JHEP Rep; 2021 Aug; 3(4):100297. PubMed ID: 34151245
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease.
    Manne V; Kowdley KV
    Clin Liver Dis; 2020 Aug; 24(3):483-492. PubMed ID: 32620284
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver disease.
    Schaefer B; Haschka D; Finkenstedt A; Petersen BS; Theurl I; Henninger B; Janecke AR; Wang CY; Lin HY; Veits L; Vogel W; Weiss G; Franke A; Zoller H
    Hum Mol Genet; 2015 Nov; 24(21):6254-63. PubMed ID: 26310624
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient patient iPSC-hepatocytes.
    Werder RB; Kaserman JE; Packer MS; Lindstrom-Vautrin J; Villacorta-Martin C; Young LE; Aratyn-Schaus Y; Gregoire F; Wilson AA
    Mol Ther; 2021 Nov; 29(11):3219-3229. PubMed ID: 34217893
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency.
    Van't Wout EF; van Schadewijk A; Lomas DA; Stolk J; Marciniak SJ; Hiemstra PS
    Eur Respir J; 2015 Feb; 45(2):365-76. PubMed ID: 25323228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis.
    Parafati M; Kirby RJ; Khorasanizadeh S; Rastinejad F; Malany S
    Dis Model Mech; 2018 Sep; 11(9):. PubMed ID: 30254132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity.
    Kaserman JE; Werder RB; Wang F; Matte T; Higgins MI; Dodge M; Lindstrom-Vautrin J; Bawa P; Hinds A; Bullitt E; Caballero IS; Shi X; Gerszten RE; Brunetti-Pierri N; Liesa M; Villacorta-Martin C; Hollenberg AN; Kotton DN; Wilson AA
    Cell Rep; 2022 Dec; 41(10):111775. PubMed ID: 36476855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alpha-1 antitrypsin deficiency and recombinant protein sources with focus on plant sources: Updates, challenges and perspectives.
    McNulty MJ; Silberstein DZ; Kuhn BT; Padgett HS; Nandi S; McDonald KA; Cross CE
    Free Radic Biol Med; 2021 Feb; 163():10-30. PubMed ID: 33279618
    [TBL] [Abstract][Full Text] [Related]  

  • 20. α(1)-antitrypsin deficiency and inflammation.
    Ekeowa UI; Marciniak SJ; Lomas DA
    Expert Rev Clin Immunol; 2011 Mar; 7(2):243-52. PubMed ID: 21426261
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.