596 related articles for article (PubMed ID: 29883946)
1. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
Mohan L; Raghav D; Ashraf SM; Sebastian J; Rathinasamy K
Biomed Pharmacother; 2018 Sep; 105():506-517. PubMed ID: 29883946
[TBL] [Abstract][Full Text] [Related]
2. Berberine Induces Toxicity in HeLa Cells through Perturbation of Microtubule Polymerization by Binding to Tubulin at a Unique Site.
Raghav D; Ashraf SM; Mohan L; Rathinasamy K
Biochemistry; 2017 May; 56(20):2594-2611. PubMed ID: 28459539
[TBL] [Abstract][Full Text] [Related]
3. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
Das Mukherjee D; Kumar NM; Tantak MP; Datta S; Ghosh Dastidar D; Kumar D; Chakrabarti G
Biochim Biophys Acta Mol Cell Res; 2020 Oct; 1867(10):118762. PubMed ID: 32502617
[TBL] [Abstract][Full Text] [Related]
4. Zerumbone, a cyclic sesquiterpene, exerts antimitotic activity in HeLa cells through tubulin binding and exhibits synergistic activity with vinblastine and paclitaxel.
Ashraf SM; Sebastian J; Rathinasamy K
Cell Prolif; 2019 Mar; 52(2):e12558. PubMed ID: 30525278
[TBL] [Abstract][Full Text] [Related]
5. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
Gupta K; Bishop J; Peck A; Brown J; Wilson L; Panda D
Biochemistry; 2004 Jun; 43(21):6645-55. PubMed ID: 15157098
[TBL] [Abstract][Full Text] [Related]
6. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.
Levrier C; Sadowski MC; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Nelson CC
Mol Cancer Ther; 2017 Jan; 16(1):3-15. PubMed ID: 27760837
[TBL] [Abstract][Full Text] [Related]
7. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative.
Sawada JI; Ishii H; Matsuno K; Sato M; Suzuki Y; Asai A
Mol Pharmacol; 2019 Nov; 96(5):609-618. PubMed ID: 31471455
[TBL] [Abstract][Full Text] [Related]
8. Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly.
Sebastian J; Rathinasamy K
Naunyn Schmiedebergs Arch Pharmacol; 2021 Jun; 394(6):1231-1249. PubMed ID: 33620548
[TBL] [Abstract][Full Text] [Related]
9. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
Bhattacharya S; Kumar NM; Ganguli A; Tantak MP; Kumar D; Chakrabarti G
PLoS One; 2013; 8(10):e76286. PubMed ID: 24116100
[TBL] [Abstract][Full Text] [Related]
10. Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity.
Gupta K; Panda D
Biochemistry; 2002 Oct; 41(43):13029-38. PubMed ID: 12390030
[TBL] [Abstract][Full Text] [Related]
11. Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.
Rathinasamy K; Jindal B; Asthana J; Singh P; Balaji PV; Panda D
BMC Cancer; 2010 May; 10():213. PubMed ID: 20482847
[TBL] [Abstract][Full Text] [Related]
12. Indicine N-oxide binds to tubulin at a distinct site and inhibits the assembly of microtubules: a mechanism for its cytotoxic activity.
Appadurai P; Rathinasamy K
Toxicol Lett; 2014 Feb; 225(1):66-77. PubMed ID: 24300171
[TBL] [Abstract][Full Text] [Related]
13. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
[TBL] [Abstract][Full Text] [Related]
14. Crocin, a carotenoid, suppresses spindle microtubule dynamics and activates the mitotic checkpoint by binding to tubulin.
Sawant AV; Srivastava S; Prassanawar SS; Bhattacharyya B; Panda D
Biochem Pharmacol; 2019 May; 163():32-45. PubMed ID: 30710515
[TBL] [Abstract][Full Text] [Related]
15. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
Jordan MA; Kamath K; Manna T; Okouneva T; Miller HP; Davis C; Littlefield BA; Wilson L
Mol Cancer Ther; 2005 Jul; 4(7):1086-95. PubMed ID: 16020666
[TBL] [Abstract][Full Text] [Related]
16. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
Acharya BR; Chatterjee A; Ganguli A; Bhattacharya S; Chakrabarti G
Biochimie; 2014 Feb; 97():78-91. PubMed ID: 24113316
[TBL] [Abstract][Full Text] [Related]
17. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
[TBL] [Abstract][Full Text] [Related]
18. Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.
Di Cesare E; Verrico A; Miele A; Giubettini M; Rovella P; Coluccia A; Famiglini V; La Regina G; Cundari E; Silvestri R; Lavia P
Oncotarget; 2017 Mar; 8(12):19738-19759. PubMed ID: 28160569
[TBL] [Abstract][Full Text] [Related]
19. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.
Jordan MA; Thrower D; Wilson L
J Cell Sci; 1992 Jul; 102 ( Pt 3)():401-16. PubMed ID: 1506423
[TBL] [Abstract][Full Text] [Related]
20. Benomyl and colchicine synergistically inhibit cell proliferation and mitosis: evidence of distinct binding sites for these agents in tubulin.
Clément MJ; Rathinasamy K; Adjadj E; Toma F; Curmi PA; Panda D
Biochemistry; 2008 Dec; 47(49):13016-25. PubMed ID: 19049291
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]