BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 29885575)

  • 1. Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
    Pedron J; Boudot C; Hutter S; Bourgeade-Delmas S; Stigliani JL; Sournia-Saquet A; Moreau A; Boutet-Robinet E; Paloque L; Mothes E; Laget M; Vendier L; Pratviel G; Wyllie S; Fairlamb A; Azas N; Courtioux B; Valentin A; Verhaeghe P
    Eur J Med Chem; 2018 Jul; 155():135-152. PubMed ID: 29885575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions.
    Pedron J; Boudot C; Bourgeade-Delmas S; Sournia-Saquet A; Paloque L; Rastegari M; Abdoulaye M; El-Kashef H; Bonduelle C; Pratviel G; Wyllie S; Fairlamb AH; Courtioux B; Verhaeghe P; Valentin A
    ChemMedChem; 2018 Oct; 13(20):2217-2228. PubMed ID: 30221468
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases.
    Fersing C; Boudot C; Pedron J; Hutter S; Primas N; Castera-Ducros C; Bourgeade-Delmas S; Sournia-Saquet A; Moreau A; Cohen A; Stigliani JL; Pratviel G; Crozet MD; Wyllie S; Fairlamb A; Valentin A; Rathelot P; Azas N; Courtioux B; Verhaeghe P; Vanelle P
    Eur J Med Chem; 2018 Sep; 157():115-126. PubMed ID: 30092366
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties.
    Fersing C; Boudot C; Paoli-Lombardo R; Primas N; Pinault E; Hutter S; Castera-Ducros C; Kabri Y; Pedron J; Bourgeade-Delmas S; Sournia-Saquet A; Stigliani JL; Valentin A; Azqueta A; Muruzabal D; Destere A; Wyllie S; Fairlamb AH; Corvaisier S; Since M; Malzert-Fréon A; Di Giorgio C; Rathelot P; Azas N; Courtioux B; Vanelle P; Verhaeghe P
    Eur J Med Chem; 2020 Nov; 206():112668. PubMed ID: 32795774
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series.
    Kieffer C; Cohen A; Verhaeghe P; Paloque L; Hutter S; Castera-Ducros C; Laget M; Rault S; Valentin A; Rathelot P; Azas N; Vanelle P
    Bioorg Med Chem; 2015 May; 23(10):2377-86. PubMed ID: 25846065
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi.
    Fersing C; Boudot C; Castera-Ducros C; Pinault E; Hutter S; Paoli-Lombardo R; Primas N; Pedron J; Seguy L; Bourgeade-Delmas S; Sournia-Saquet A; Stigliani JL; Brossas JY; Paris L; Valentin A; Wyllie S; Fairlamb AH; Boutet-Robinet É; Corvaisier S; Since M; Malzert-Fréon A; Destere A; Mazier D; Rathelot P; Courtioux B; Azas N; Verhaeghe P; Vanelle P
    Eur J Med Chem; 2020 Sep; 202():112558. PubMed ID: 32652409
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of a new antileishmanial hit in 8-nitroquinoline series.
    Paloque L; Verhaeghe P; Casanova M; Castera-Ducros C; Dumètre A; Mbatchi L; Hutter S; Kraiem-M'rabet M; Laget M; Remusat V; Rault S; Rathelot P; Azas N; Vanelle P
    Eur J Med Chem; 2012 Aug; 54():75-86. PubMed ID: 22608675
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New 8-Nitroquinolinone Derivative Displaying Submicromolar
    Pedron J; Boudot C; Brossas JY; Pinault E; Bourgeade-Delmas S; Sournia-Saquet A; Boutet-Robinet E; Destere A; Tronnet A; Bergé J; Bonduelle C; Deraeve C; Pratviel G; Stigliani JL; Paris L; Mazier D; Corvaisier S; Since M; Malzert-Fréon A; Wyllie S; Milne R; Fairlamb AH; Valentin A; Courtioux B; Verhaeghe P
    ACS Med Chem Lett; 2020 Apr; 11(4):464-472. PubMed ID: 32292551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series.
    Kieffer C; Cohen A; Verhaeghe P; Hutter S; Castera-Ducros C; Laget M; Remusat V; M'Rabet MK; Rault S; Rathelot P; Azas N; Vanelle P
    Eur J Med Chem; 2015 Mar; 92():282-94. PubMed ID: 25559208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro evaluation of arylsubstituted imidazoles derivatives as antiprotozoal agents and docking studies on sterol 14α-demethylase (CYP51) from Trypanosoma cruzi, Leishmania infantum, and Trypanosoma brucei.
    Rojas Vargas JA; López AG; Pérez Y; Cos P; Froeyen M
    Parasitol Res; 2019 May; 118(5):1533-1548. PubMed ID: 30903349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents.
    Bouton J; Maes L; Karalic I; Caljon G; Van Calenbergh S
    Eur J Med Chem; 2021 Feb; 212():113101. PubMed ID: 33385837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
    Di Pietro O; Vicente-García E; Taylor MC; Berenguer D; Viayna E; Lanzoni A; Sola I; Sayago H; Riera C; Fisa R; Clos MV; Pérez B; Kelly JM; Lavilla R; Muñoz-Torrero D
    Eur J Med Chem; 2015 Nov; 105():120-37. PubMed ID: 26479031
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of novel guttiferone A derivatives: in-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani.
    Fromentin Y; Gaboriaud-Kolar N; Lenta BN; Wansi JD; Buisson D; Mouray E; Grellier P; Loiseau PM; Lallemand MC; Michel S
    Eur J Med Chem; 2013 Jul; 65():284-94. PubMed ID: 23727538
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New antiprotozoal agents: their synthesis and biological evaluations.
    Upadhayaya RS; Dixit SS; Földesi A; Chattopadhyaya J
    Bioorg Med Chem Lett; 2013 May; 23(9):2750-8. PubMed ID: 23518280
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nongenotoxic 3-Nitroimidazo[1,2-
    Fersing C; Basmaciyan L; Boudot C; Pedron J; Hutter S; Cohen A; Castera-Ducros C; Primas N; Laget M; Casanova M; Bourgeade-Delmas S; Piednoel M; Sournia-Saquet A; Belle Mbou V; Courtioux B; Boutet-Robinet É; Since M; Milne R; Wyllie S; Fairlamb AH; Valentin A; Rathelot P; Verhaeghe P; Vanelle P; Azas N
    ACS Med Chem Lett; 2019 Jan; 10(1):34-39. PubMed ID: 30655943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Quinoxaline derivatives as potential antitrypanosomal and antileishmanial agents.
    Cogo J; Cantizani J; Cotillo I; Sangi DP; Corrêa AG; Ueda-Nakamura T; Filho BPD; Martín JJ; Nakamura CV
    Bioorg Med Chem; 2018 Aug; 26(14):4065-4072. PubMed ID: 30100019
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel quinoline derivatives with broad-spectrum antiprotozoal activities.
    Hartman CB; Dube PS; Legoabe LJ; Van Pelt N; Matheeussen A; Caljon G; Beteck RM
    Arch Pharm (Weinheim); 2024 Jun; 357(6):e2300319. PubMed ID: 38396284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and in vitro antikinetoplastid evaluation of N-acylated putrescine, spermidine and spermine derivatives.
    Jagu E; Djilali R; Pomel S; Ramiandrasoa F; Pethe S; Labruère R; Loiseau PM; Blonski C
    Bioorg Med Chem Lett; 2015 Jan; 25(2):207-9. PubMed ID: 25499437
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives.
    Guillon J; Cohen A; Das RN; Boudot C; Gueddouda NM; Moreau S; Ronga L; Savrimoutou S; Basmaciyan L; Tisnerat C; Mestanier S; Rubio S; Amaziane S; Dassonville-Klimpt A; Azas N; Courtioux B; Mergny JL; Mullié C; Sonnet P
    Chem Biol Drug Des; 2018 May; 91(5):974-995. PubMed ID: 29266861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines.
    Manda S; Khan SI; Jain SK; Mohammed S; Tekwani BL; Khan IA; Vishwakarma RA; Bharate SB
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3247-50. PubMed ID: 24980054
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.