149 related articles for article (PubMed ID: 29886082)
1. Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors.
Tóth K; Höfner G; Wanner KT
Bioorg Med Chem; 2018 Jul; 26(12):3668-3687. PubMed ID: 29886082
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a trans-alkene spacer as potent GABA uptake inhibitors.
Tóth K; Höfner G; Wanner KT
Bioorg Med Chem; 2018 Dec; 26(22):5944-5961. PubMed ID: 30442505
[TBL] [Abstract][Full Text] [Related]
3. Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents.
Lutz T; Wein T; Höfner G; Wanner KT
ChemMedChem; 2017 Mar; 12(5):362-371. PubMed ID: 28125164
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of N-substituted nipecotic acid derivatives with an unsymmetrical bis-aromatic residue attached to a vinyl ether spacer as potential GABA uptake inhibitors.
Quandt G; Höfner G; Wanner KT
Bioorg Med Chem; 2013 Jun; 21(11):3363-78. PubMed ID: 23598250
[TBL] [Abstract][Full Text] [Related]
5. Generation and screening of pseudostatic hydrazone libraries derived from 5-substituted nipecotic acid derivatives at the GABA transporter mGAT4.
Hauke TJ; Höfner G; Wanner KT
Bioorg Med Chem; 2019 Jan; 27(1):144-152. PubMed ID: 30503411
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a cis-alkene spacer as GABA uptake inhibitors.
Tóth K; Höfner G; Wanner KT
Bioorg Med Chem; 2019 Mar; 27(5):822-831. PubMed ID: 30718063
[TBL] [Abstract][Full Text] [Related]
7. Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors.
Pizzi DA; Leslie CP; Di Fabio R; Seri C; Bernasconi G; Squaglia M; Carnevale G; Falchi A; Greco E; Mangiarini L; Negri M
Bioorg Med Chem Lett; 2011 Jan; 21(1):602-5. PubMed ID: 21134748
[TBL] [Abstract][Full Text] [Related]
8. MS-Based Screening of 5-Substituted Nipecotic Acid Derived Hydrazone Libraries as Ligands of the GABA Transporter 1.
Hauke TJ; Höfner G; Wanner KT
ChemMedChem; 2019 Mar; 14(5):583-593. PubMed ID: 30663849
[TBL] [Abstract][Full Text] [Related]
9. 2-Substituted 4-hydroxybutanamides as potential inhibitors of γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.
Kowalczyk P; Sałat K; Höfner GC; Guzior N; Filipek B; Wanner KT; Kulig K
Bioorg Med Chem; 2013 Sep; 21(17):5154-67. PubMed ID: 23859778
[TBL] [Abstract][Full Text] [Related]
10. Development of an (S)-1-{2-[tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(S)-SNAP-5114] carba analogue inhibitor for murine γ-aminobutyric acid transporter type 4.
Pabel J; Faust M; Prehn C; Wörlein B; Allmendinger L; Höfner G; Wanner KT
ChemMedChem; 2012 Jul; 7(7):1245-55. PubMed ID: 22544452
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents.
Seth A; Sharma PA; Tripathi A; Choubey PK; Srivastava P; Tripathi PN; Shrivastava SK
Med Chem; 2018; 14(4):409-426. PubMed ID: 29336266
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.
Kragler A; Höfner G; Wanner KT
Eur J Med Chem; 2008 Nov; 43(11):2404-11. PubMed ID: 18395300
[TBL] [Abstract][Full Text] [Related]
13. Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
Zaręba P; Gryzło B; Malawska K; Sałat K; Höfner GC; Nowaczyk A; Fijałkowski Ł; Rapacz A; Podkowa A; Furgała A; Żmudzki P; Wanner KT; Malawska B; Kulig K
Eur J Med Chem; 2020 Feb; 188():111920. PubMed ID: 31901745
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of 4-substituted nipecotic acid derivatives and their evaluation as potential GABA uptake inhibitors.
Hellenbrand T; Höfner G; Wein T; Wanner KT
Bioorg Med Chem; 2016 May; 24(9):2072-96. PubMed ID: 27039250
[TBL] [Abstract][Full Text] [Related]
15. First photoswitchable neurotransmitter transporter inhibitor: light-induced control of γ-aminobutyric acid transporter 1 (GAT1) activity in mouse brain.
Quandt G; Höfner G; Pabel J; Dine J; Eder M; Wanner KT
J Med Chem; 2014 Aug; 57(15):6809-21. PubMed ID: 25025595
[TBL] [Abstract][Full Text] [Related]
16. Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3.
Damgaard M; Al-Khawaja A; Vogensen SB; Jurik A; Sijm M; Lie ME; Bæk MI; Rosenthal E; Jensen AA; Ecker GF; Frølund B; Wellendorph P; Clausen RP
ACS Chem Neurosci; 2015 Sep; 6(9):1591-9. PubMed ID: 26154082
[TBL] [Abstract][Full Text] [Related]
17. Structure activity relationship of selective GABA uptake inhibitors.
Vogensen SB; Jørgensen L; Madsen KK; Jurik A; Borkar N; Rosatelli E; Nielsen B; Ecker GF; Schousboe A; Clausen RP
Bioorg Med Chem; 2015 May; 23(10):2480-8. PubMed ID: 25882526
[TBL] [Abstract][Full Text] [Related]
18. Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives by Suzuki-Miyaura Cross-Coupling Reactions.
Petrera M; Wein T; Allmendinger L; Sindelar M; Pabel J; Höfner G; Wanner KT
ChemMedChem; 2016 Mar; 11(5):519-38. PubMed ID: 26683881
[TBL] [Abstract][Full Text] [Related]
19. N-Substituted Nipecotic Acids as (S)-SNAP-5114 Analogues with Modified Lipophilic Domains.
Böck MC; Höfner G; Wanner KT
ChemMedChem; 2020 May; 15(9):756-771. PubMed ID: 32187815
[TBL] [Abstract][Full Text] [Related]
20. Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.
Schaffert ES; Höfner G; Wanner KT
Bioorg Med Chem; 2011 Nov; 19(21):6492-504. PubMed ID: 21940173
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
