BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 29886322)

  • 1. Synthesis and biological evaluation of podophyllotoxin derivatives as selective antitumor agents.
    Wu GR; Xu B; Yang YQ; Zhang XY; Fang K; Ma T; Wang H; Xue NN; Chen M; Guo WB; Jia XH; Wang PL; Lei HM
    Eur J Med Chem; 2018 Jul; 155():183-196. PubMed ID: 29886322
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activity evaluation of podophyllotoxin-linked bile acid derivatives as potential anti-liver cancer agents.
    Cai DS; Lou SY; Huo S; Yang YQ; Gao F; Pi WM; Chen KD; Wang C; Yang XY; Jiao JY; Xu B; Wang PL; Lei HM
    Bioorg Chem; 2022 Nov; 128():106066. PubMed ID: 35964500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological activity of glycyrrhetinic acid derivatives as antitumor agents.
    Zhou F; Wu GR; Cai DS; Xu B; Yan MM; Ma T; Guo WB; Zhang WX; Huang XM; Jia XH; Yang YQ; Gao F; Wang PL; Lei HM
    Eur J Med Chem; 2019 Sep; 178():623-635. PubMed ID: 31226654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway.
    Zhao Y; Li D; Wei M; Du R; Yan Z
    Bioorg Med Chem Lett; 2021 Aug; 46():128174. PubMed ID: 34098082
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4β-[(4-Alkyl)-1,2,3-triazol-1-yl] podophyllotoxins as anticancer compounds: design, synthesis and biological evaluation.
    Reddy DM; Srinivas J; Chashoo G; Saxena AK; Sampath Kumar HM
    Eur J Med Chem; 2011 Jun; 46(6):1983-91. PubMed ID: 21477899
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ; Sun WX; Wang X; Zhang YH; Qiu HY; Qi JL; Pang YJ; Lu GH; Wang XM; Yu FG; Yang YH
    Chem Biol Drug Des; 2017 Aug; 90(2):236-243. PubMed ID: 28079286
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
    Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
    Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and anti-cancer activity evaluation of podophyllotoxin-norcantharidin hybrid drugs.
    Han HW; Qiu HY; Hu C; Sun WX; Yang RW; Qi JL; Wang XM; Lu GH; Yang YH
    Bioorg Med Chem Lett; 2016 Jul; 26(14):3237-3242. PubMed ID: 27262599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and cytotoxic activity on human cancer cells of carbamate derivatives of 4β-(1,2,3-triazol-1-yl)podophyllotoxin.
    Liu JF; Sang CY; Xu XH; Zhang LL; Yang X; Hui L; Zhang JB; Chen SW
    Eur J Med Chem; 2013 Jun; 64():621-8. PubMed ID: 23711769
    [TBL] [Abstract][Full Text] [Related]  

  • 11. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
    Shankaraiah N; Kumar NP; Amula SB; Nekkanti S; Jeengar MK; Naidu VG; Reddy TS; Kamal A
    Bioorg Med Chem Lett; 2015 Oct; 25(19):4239-44. PubMed ID: 26292628
    [TBL] [Abstract][Full Text] [Related]  

  • 12. One-pot synthesis and biological evaluation of N-(aminosulfonyl)-4-podophyllotoxin carbamates as potential anticancer agents.
    Xu XH; Guan XW; Feng SL; Ma YZ; Chen SW; Hui L
    Bioorg Med Chem Lett; 2017 Jul; 27(13):2890-2894. PubMed ID: 28512026
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and anticancer activity of dimeric podophyllotoxin derivatives.
    Zi CT; Yang L; Xu FQ; Dong FW; Yang D; Li Y; Ding ZT; Zhou J; Jiang ZH; Hu JM
    Drug Des Devel Ther; 2018; 12():3393-3406. PubMed ID: 30349193
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y; Wei D; Zhao Y; Cheng W; Lu Y; Ma Y; Li X; Han C; Wei Y; Cao H; Zhao C
    Bioorg Med Chem; 2012 Nov; 20(21):6285-95. PubMed ID: 23022053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of a novel artesunate-podophyllotoxin conjugate as anticancer agent.
    Zhang L; Chen F; Zhang Z; Chen Y; Wang J
    Bioorg Med Chem Lett; 2016 Jan; 26(1):38-42. PubMed ID: 26615886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and cytotoxicity evaluation of novel podophyllotoxin derivatives.
    Chengniu W; Zhonghua W; Yu Z; Chunyan N; Xiaodong Z; Li Z
    Arch Pharm (Weinheim); 2011 Nov; 344(11):735-40. PubMed ID: 21887802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of hybrid 4-deoxypodophyllotoxin-5-fluorouracil compounds that inhibit cellular migration and induce cell cycle arrest.
    Guan XW; Xu XH; Feng SL; Tang ZB; Chen SW; Hui L
    Bioorg Med Chem Lett; 2016 Mar; 26(6):1561-1566. PubMed ID: 26873416
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of piperazine acetate podophyllotoxin ester derivatives targeting tubulin depolymerization as new anticancer agents.
    Sun WX; Ji YJ; Wan Y; Han HW; Lin HY; Lu GH; Qi JL; Wang XM; Yang YH
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4066-4074. PubMed ID: 28757065
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
    Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and bioevaluation and doking study of 1H-pyrrolo[2,3-b]pyridine derivatives bearing aromatic hydrazone moiety as c-Met inhibitors.
    Wang W; Xu S; Duan Y; Liu X; Li X; Wang C; Zhao B; Zheng P; Zhu W
    Eur J Med Chem; 2018 Feb; 145():315-327. PubMed ID: 29331754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.