139 related articles for article (PubMed ID: 29887511)
1. Design, synthesis, and biological evaluation of novel biphenyl-4-carboxamide derivatives as orally available TRPV1 antagonists.
Oka H; Yonezawa K; Kamikawa A; Ikegai K; Asai N; Shirakami S; Miyamoto S; Watanabe T; Kiso T; Takemoto Y; Tamura S; Kuramochi T
Bioorg Med Chem; 2018 Jul; 26(12):3716-3726. PubMed ID: 29887511
[TBL] [Abstract][Full Text] [Related]
2. Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect.
Watabiki T; Kiso T; Kuramochi T; Yonezawa K; Tsuji N; Kohara A; Kakimoto S; Aoki T; Matsuoka N
J Pharmacol Exp Ther; 2011 Mar; 336(3):743-50. PubMed ID: 21098091
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of Analogues of BCTC Incorporating a Pyrrolidinyl Linker and Biological Evaluation as Transient Receptor Potential Vanilloid 1 Antagonists.
Yan L; Wang J; Pan M; Qiu Q; Huang W; Qian H
Chem Biol Drug Des; 2016 Feb; 87(2):306-11. PubMed ID: 26360809
[TBL] [Abstract][Full Text] [Related]
4. Discovery of potent, soluble and orally active TRPV1 antagonists. Structure-activity relationships of a series of isoxazoles.
Ratcliffe P; Abernethy L; Ansari N; Cameron K; Clarkson T; Dempster M; Dunn D; Easson AM; Edwards D; Everett K; Feilden H; Ho KK; Kultgen S; Littlewood P; Maclean J; McArthur D; McGregor D; McLuskey H; Neagu I; Nimz O; Nisbet LA; Ohlmeyer M; Palin R; Pham Q; Rong Y; Roughton A; Sammons M; Swanson R; Tracey H; Walker G
Bioorg Med Chem Lett; 2011 Aug; 21(15):4652-7. PubMed ID: 21723725
[TBL] [Abstract][Full Text] [Related]
5. Discovery of piperidine carboxamide TRPV1 antagonists.
Cheung WS; Calvo RR; Tounge BA; Zhang SP; Stone DR; Brandt MR; Hutchinson T; Flores CM; Player MR
Bioorg Med Chem Lett; 2008 Aug; 18(16):4569-72. PubMed ID: 18662879
[TBL] [Abstract][Full Text] [Related]
6. Discovery of indane propanamides as potent and selective TRPV1 antagonists.
Ahn S; Kim YS; Kim MS; Ann J; Ha H; Yoo YD; Kim YH; Blumberg PM; Frank-Foltyn R; Bahrenberg G; Stockhausen H; Christoph T; Lee J
Bioorg Med Chem Lett; 2020 Feb; 30(3):126838. PubMed ID: 31864799
[TBL] [Abstract][Full Text] [Related]
7. TRPV1 modulators: Synthesis and in vitro evaluation of 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives.
Congiu C; Onnis V; Balboni G; Schiano-Moriello A; Di Marzo V; De Petrocellis L
Eur J Med Chem; 2015 Jul; 100():129-38. PubMed ID: 26079089
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of novel 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole triazole derivatives as potent TRPV1 antagonists.
Li J; Nie C; Qiao Y; Hu J; Li Q; Wang Q; Pu X; Yan L; Qian H
Eur J Med Chem; 2019 Sep; 178():433-445. PubMed ID: 31202991
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists.
Li FN; Kim NJ; Paek SM; Kwon DY; Min KH; Jeong YS; Kim SY; Park YH; Kim HD; Park HG; Suh YG
Bioorg Med Chem; 2009 May; 17(10):3557-67. PubMed ID: 19398205
[TBL] [Abstract][Full Text] [Related]
10. Structure-activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists.
Palin R; Abernethy L; Ansari N; Cameron K; Clarkson T; Dempster M; Dunn D; Easson AM; Edwards D; Maclean J; Everett K; Feilden H; Ho KK; Kultgen S; Littlewood P; McArthur D; McGregor D; McLuskey H; Neagu I; Neale S; Nisbet LA; Ohlmeyer M; Pham Q; Ratcliffe P; Rong Y; Roughton A; Sammons M; Swanson R; Tracey H; Walker G
Bioorg Med Chem Lett; 2011 Feb; 21(3):892-8. PubMed ID: 21236666
[TBL] [Abstract][Full Text] [Related]
11. 4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands.
Kim C; Ann J; Lee S; Kim E; Choi S; Blumberg PM; Frank-Foltyn R; Bahrenberg G; Stockhausen H; Christoph T; Lee J
Bioorg Med Chem; 2018 Aug; 26(15):4509-4517. PubMed ID: 30078610
[TBL] [Abstract][Full Text] [Related]
12. TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides.
Ha TH; Ryu H; Kim SE; Kim HS; Ann J; Tran PT; Hoang VH; Son K; Cui M; Choi S; Blumberg PM; Frank R; Bahrenberg G; Schiene K; Christoph T; Frormann S; Lee J
Bioorg Med Chem; 2013 Nov; 21(21):6657-64. PubMed ID: 24035514
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists.
Xi N; Bo Y; Doherty EM; Fotsch C; Gavva NR; Han N; Hungate RW; Klionsky L; Liu Q; Tamir R; Xu S; Treanor JJ; Norman MH
Bioorg Med Chem Lett; 2005 Dec; 15(23):5211-7. PubMed ID: 16203144
[TBL] [Abstract][Full Text] [Related]
14. Identification of potent, soluble, and orally active TRPV1 antagonists.
Ratcliffe P; Maclean J; Abernethy L; Clarkson T; Dempster M; Easson AM; Edwards D; Everett K; Feilden H; Littlewood P; McArthur D; McGregor D; McLuskey H; Nimz O; Nisbet LA; Palin R; Tracey H; Walker G
Bioorg Med Chem Lett; 2011 Apr; 21(8):2559-63. PubMed ID: 21435873
[TBL] [Abstract][Full Text] [Related]
15. Discovery of novel 5,5-diarylpentadienamides as orally available transient receptor potential vanilloid 1 (TRPV1) antagonists.
Saku O; Ishida H; Atsumi E; Sugimoto Y; Kodaira H; Kato Y; Shirakura S; Nakasato Y
J Med Chem; 2012 Apr; 55(7):3436-51. PubMed ID: 22394104
[TBL] [Abstract][Full Text] [Related]
16. Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.
Besidski Y; Brown W; Bylund J; Dabrowski M; Dautrey S; Harter M; Horoszok L; Hu Y; Johnson D; Johnstone S; Jones P; Leclerc S; Kolmodin K; Kers I; Labarre M; Labrecque D; Laird J; Lundström T; Martino J; Maudet M; Munro A; Nylöf M; Penwell A; Rotticci D; Slaitas A; Sundgren-Andersson A; Svensson M; Terp G; Villanueva H; Walpole C; Zemribo R; Griffin AM
Bioorg Med Chem Lett; 2012 Oct; 22(19):6205-11. PubMed ID: 22939234
[TBL] [Abstract][Full Text] [Related]
17. Trisubstituted pyrimidines as transient receptor potential vanilloid 1 (TRPV1) antagonists with improved solubility.
Wang X; Chakrabarti PP; Ognyanov VI; Pettus LH; Tamir R; Tan H; Tang P; Treanor JJ; Gavva NR; Norman MH
Bioorg Med Chem Lett; 2007 Dec; 17(23):6539-45. PubMed ID: 17937985
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological characterization of (3S)-3-(hydroxymethyl)-4-(5-methylpyridin-2-yl)-N-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide (JTS-653), a novel transient receptor potential vanilloid 1 antagonist.
Kitagawa Y; Miyai A; Usui K; Hamada Y; Deai K; Wada M; Koga Y; Sakata M; Hayashi M; Tominaga M; Matsushita M
J Pharmacol Exp Ther; 2012 Aug; 342(2):520-8. PubMed ID: 22588258
[TBL] [Abstract][Full Text] [Related]
19. Novel benzodiazepines derivatives as analgesic modulating for Transient receptor potential vanilloid 1.
Liu Y; Liao C; Zhou J; Liu C; Li Q; Jiang Y; Qian H
Bioorg Med Chem; 2018 Aug; 26(15):4567-4573. PubMed ID: 30093345
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel 2',4'-dimethyl-[4,5'-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 1.
Tsuno N; Yukimasa A; Yoshida O; Ichihashi Y; Inoue T; Ueno T; Yamaguchi H; Matsuda H; Funaki S; Yamanada N; Tanimura M; Nagamatsu D; Nishimura Y; Ito T; Soga M; Horita N; Yamamoto M; Hinata M; Imai M; Morioka Y; Kanemasa T; Sakaguchi G; Iso Y
Bioorg Med Chem Lett; 2016 Oct; 26(20):4930-4935. PubMed ID: 27637151
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
