BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

499 related articles for article (PubMed ID: 29894679)

  • 1. LRRK2 and mitochondria: Recent advances and current views.
    Singh A; Zhi L; Zhang H
    Brain Res; 2019 Jan; 1702():96-104. PubMed ID: 29894679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants.
    Verma M; Callio J; Otero PA; Sekler I; Wills ZP; Chu CT
    J Neurosci; 2017 Nov; 37(46):11151-11165. PubMed ID: 29038245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants.
    Ilieva NM; Hoffman EK; Ghalib MA; Greenamyre JT; De Miranda BR
    Neurobiol Dis; 2024 Jun; 196():106522. PubMed ID: 38705492
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Parkinson's disease and mitophagy: an emerging role for LRRK2.
    Singh F; Ganley IG
    Biochem Soc Trans; 2021 Apr; 49(2):551-562. PubMed ID: 33769432
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Cell Biology of LRRK2 in Parkinson's Disease.
    Usmani A; Shavarebi F; Hiniker A
    Mol Cell Biol; 2021 Apr; 41(5):. PubMed ID: 33526455
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dietary Amino Acids Impact LRRK2-Induced Neurodegeneration in Parkinson's Disease Models.
    Chittoor-Vinod VG; Villalobos-Cantor S; Roshak H; Shea K; Abalde-Atristain L; Martin I
    J Neurosci; 2020 Aug; 40(32):6234-6249. PubMed ID: 32605938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality.
    Walter J; Bolognin S; Antony PMA; Nickels SL; Poovathingal SK; Salamanca L; Magni S; Perfeito R; Hoel F; Qing X; Jarazo J; Arias-Fuenzalida J; Ignac T; Monzel AS; Gonzalez-Cano L; Pereira de Almeida L; Skupin A; Tronstad KJ; Schwamborn JC
    Stem Cell Reports; 2019 May; 12(5):878-889. PubMed ID: 30982740
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2
    Juárez-Flores DL; González-Casacuberta I; Ezquerra M; Bañó M; Carmona-Pontaque F; Catalán-García M; Guitart-Mampel M; Rivero JJ; Tobias E; Milisenda JC; Tolosa E; Marti MJ; Fernández-Santiago R; Cardellach F; Morén C; Garrabou G
    J Transl Med; 2018 Jun; 16(1):160. PubMed ID: 29884186
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
    Nguyen APT; Tsika E; Kelly K; Levine N; Chen X; West AB; Boularand S; Barneoud P; Moore DJ
    Proc Natl Acad Sci U S A; 2020 Jul; 117(29):17296-17307. PubMed ID: 32631998
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm.
    Esteves AR; G-Fernandes M; Santos D; Januário C; Cardoso SM
    Mol Neurobiol; 2015 Dec; 52(3):1804-1820. PubMed ID: 25394383
    [TBL] [Abstract][Full Text] [Related]  

  • 11.
    Wauters F; Cornelissen T; Imberechts D; Martin S; Koentjoro B; Sue C; Vangheluwe P; Vandenberghe W
    Autophagy; 2020 Feb; 16(2):203-222. PubMed ID: 30945962
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to
    Weindel CG; Bell SL; Vail KJ; West KO; Patrick KL; Watson RO
    Elife; 2020 Feb; 9():. PubMed ID: 32057291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms of LRRK2-mediated neurodegeneration.
    Tsika E; Moore DJ
    Curr Neurol Neurosci Rep; 2012 Jun; 12(3):251-60. PubMed ID: 22441981
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The parkinsonian LRRK2 R1441G mutation shows macroautophagy-mitophagy dysregulation concomitant with endoplasmic reticulum stress.
    Yakhine-Diop SMS; Rodríguez-Arribas M; Canales-Cortés S; Martínez-Chacón G; Uribe-Carretero E; Blanco-Benítez M; Duque-González G; Paredes-Barquero M; Alegre-Cortés E; Climent V; Aiastui A; López de Munain A; Bravo-San Pedro JM; Niso-Santano M; Fuentes JM; González-Polo RA
    Cell Biol Toxicol; 2022 Oct; 38(5):889-911. PubMed ID: 34060004
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease.
    Bonello F; Hassoun SM; Mouton-Liger F; Shin YS; Muscat A; Tesson C; Lesage S; Beart PM; Brice A; Krupp J; Corvol JC; Corti O
    Hum Mol Genet; 2019 May; 28(10):1645-1660. PubMed ID: 30629163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Altered ER-mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models.
    Lee KS; Huh S; Lee S; Wu Z; Kim AK; Kang HY; Lu B
    Proc Natl Acad Sci U S A; 2018 Sep; 115(38):E8844-E8853. PubMed ID: 30185553
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.
    Pan PY; Li X; Wang J; Powell J; Wang Q; Zhang Y; Chen Z; Wicinski B; Hof P; Ryan TA; Yue Z
    J Neurosci; 2017 Nov; 37(47):11366-11376. PubMed ID: 29054882
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease.
    Tozzi A; Tantucci M; Marchi S; Mazzocchetti P; Morari M; Pinton P; Mancini A; Calabresi P
    Cell Death Dis; 2018 Feb; 9(2):204. PubMed ID: 29434188
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease.
    Zuo L; Motherwell MS
    Gene; 2013 Dec; 532(1):18-23. PubMed ID: 23954870
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson's Disease.
    Nguyen M; Wong YC; Ysselstein D; Severino A; Krainc D
    Trends Neurosci; 2019 Feb; 42(2):140-149. PubMed ID: 30509690
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.