BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 2989523)

  • 1. Synthesis and antiherpetic activity of (S)-, (R)-, and (+/-)-9-[(2,3-dihydroxy-1-propoxy)methyl]guanine, linear isomers of 2'-nor-2'-deoxyguanosine.
    Ashton WT; Canning LF; Reynolds GF; Tolman RL; Karkas JD; Liou R; Davies ME; DeWitt CM; Perry HC; Field AK
    J Med Chem; 1985 Jul; 28(7):926-33. PubMed ID: 2989523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.
    Field AK; Davies ME; DeWitt C; Perry HC; Liou R; Germershausen J; Karkas JD; Ashton WT; Johnston DB; Tolman RL
    Proc Natl Acad Sci U S A; 1983 Jul; 80(13):4139-43. PubMed ID: 6306664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enzymatic phosphorylation of the antiherpetic agent 9-[(2,3-dihydroxy-1-propoxy)methyl]guanine.
    Karkas JD; Ashton WT; Canning LF; Liou R; Germershausen J; Bostedor R; Arison B; Field AK; Tolman RL
    J Med Chem; 1986 May; 29(5):842-8. PubMed ID: 3009816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antiherpes simplex virus activity of 9-[(1,3-dihydroxy-2-propylthio)methyl]guanine.
    McGee DP; Martin JC; Smee DF; Matthews TR; Verheyden JP
    J Med Chem; 1985 Sep; 28(9):1242-5. PubMed ID: 2993615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the modes of antiviral action of 2'-nor-deoxyguanosine and its cyclic phosphate, 2'-nor-cyclic GMP.
    Germershausen J; Bostedor R; Liou R; Field AK; Wagner AF; MacCoss M; Tolman RL; Karkas JD
    Antimicrob Agents Chemother; 1986 Jun; 29(6):1025-31. PubMed ID: 3015013
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and anti-herpes-virus activity of acyclic 2'-deoxyguanosine analogues related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine.
    Martin JC; McGee DP; Jeffrey GA; Hobbs DW; Smee DF; Matthews TR; Verheyden JP
    J Med Chem; 1986 Aug; 29(8):1384-9. PubMed ID: 3016263
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A comparison of the antiviral agents 2'-nor-2'-deoxyguanosine and acyclovir: uptake and phosphorylation in tissue culture and kinetics of in vitro inhibition of viral and cellular DNA polymerases by their respective triphosphates.
    Germershausen J; Bostedor R; Field AK; Perry H; Liou R; Bull H; Tolman RL; Karkas JD
    Biochem Biophys Res Commun; 1983 Oct; 116(2):360-7. PubMed ID: 6316950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antiviral activity of various esters of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine.
    Martin JC; Tippie MA; McGee DP; Verheyden JP
    J Pharm Sci; 1987 Feb; 76(2):180-4. PubMed ID: 3033195
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Broad-spectrum antiviral activity of the acyclic guanosine phosphonate (R,S)-HPMPG.
    Terry BJ; Mazina KE; Tuomari AV; Haffey ML; Hagen M; Feldman A; Slusarchyk WA; Young MG; Zahler R; Field AK
    Antiviral Res; 1988 Dec; 10(4-5):235-51. PubMed ID: 2852486
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation by thymidine kinase and potent antiherpetic activity of 2'-nor-2'-deoxyguanosine (2'NDG).
    Ashton WT; Karkas JD; Field AK; Tolman RL
    Biochem Biophys Res Commun; 1982 Oct; 108(4):1716-21. PubMed ID: 6295389
    [No Abstract]   [Full Text] [Related]  

  • 11. 2'-nor-cGMP, a new cyclic derivative of 2'NDG, inhibits HSV-1 replication in vitro and in the mouse keratitis model.
    Gordon YJ; Capone A; Sheppard J; Gordon A; Romanowski E; Araullo-Cruz T
    Curr Eye Res; 1987 Jan; 6(1):247-53. PubMed ID: 3030646
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locus.
    Crumpacker CS; Kowalsky PN; Oliver SA; Schnipper LE; Field AK
    Proc Natl Acad Sci U S A; 1984 Mar; 81(5):1556-60. PubMed ID: 6324203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1.
    Cheng YC; Huang ES; Lin JC; Mar EC; Pagano JS; Dutschman GE; Grill SP
    Proc Natl Acad Sci U S A; 1983 May; 80(9):2767-70. PubMed ID: 6302704
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine: a new potent and selective antiherpes agent.
    Martin JC; Dvorak CA; Smee DF; Matthews TR; Verheyden JP
    J Med Chem; 1983 May; 26(5):759-61. PubMed ID: 6302255
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antiherpetic activity of (+/-)-9-[[(Z)-2-(hydroxymethyl)cyclopropyl]methyl]guanine and related compounds.
    Ashton WT; Meurer LC; Cantone CL; Field AK; Hannah J; Karkas JD; Liou R; Patel GF; Perry HC; Wagner AF
    J Med Chem; 1988 Dec; 31(12):2304-15. PubMed ID: 2848125
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxy guanosines.
    Borthwick AD; Kirk BE; Biggadike K; Exall AM; Butt S; Roberts SM; Knight DJ; Coates JA; Ryan DM
    J Med Chem; 1991 Mar; 34(3):907-14. PubMed ID: 1848298
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2'-Nor-cGMP: a seco-cyclic nucleotide with powerful anti-DNA-viral activity.
    Tolman RL; Field AK; Karkas JD; Wagner AF; Germershausen J; Crumpacker C; Scolnick EM
    Biochem Biophys Res Commun; 1985 May; 128(3):1329-35. PubMed ID: 2988534
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antiherpetic activity and mechanism of action of 9-(4-hydroxybutyl)guanine.
    Larsson A; Alenius S; Johansson NG; Oberg B
    Antiviral Res; 1983 Aug; 3(2):77-86. PubMed ID: 6312878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modifications on the heterocyclic base of acyclovir: syntheses and antiviral properties.
    Beauchamp LM; Dolmatch BL; Schaeffer HJ; Collins P; Bauer DJ; Keller PM; Fyfe JA
    J Med Chem; 1985 Aug; 28(8):982-7. PubMed ID: 2991522
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine.
    Prisbe EJ; Martin JC; McGee DP; Barker MF; Smee DF; Duke AE; Matthews TR; Verheyden JP
    J Med Chem; 1986 May; 29(5):671-5. PubMed ID: 3009811
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.