These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. McClenahan SJ; Kent CN; Kharade SV; Isaeva E; Williams JC; Han C; Terker A; Gresham R; Lazarenko RM; Days EL; Romaine IM; Bauer JA; Boutaud O; Sulikowski GA; Harris R; Weaver CD; Staruschenko A; Lindsley CW; Denton JS Mol Pharmacol; 2022 May; 101(5):357-370. PubMed ID: 35246480 [TBL] [Abstract][Full Text] [Related]
5. Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1. Raphemot R; Kadakia RJ; Olsen ML; Banerjee S; Days E; Smith SS; Weaver CD; Denton JS Assay Drug Dev Technol; 2013; 11(9-10):532-43. PubMed ID: 24266659 [TBL] [Abstract][Full Text] [Related]
6. High-potency block of Kir4.1 channels by pentamidine: Molecular basis. Aréchiga-Figueroa IA; Marmolejo-Murillo LG; Cui M; Delgado-Ramírez M; van der Heyden MAG; Sánchez-Chapula JA; Rodríguez-Menchaca AA Eur J Pharmacol; 2017 Nov; 815():56-63. PubMed ID: 28993158 [TBL] [Abstract][Full Text] [Related]
7. Mutational and in silico analyses for antidepressant block of astroglial inward-rectifier Kir4.1 channel. Furutani K; Ohno Y; Inanobe A; Hibino H; Kurachi Y Mol Pharmacol; 2009 Jun; 75(6):1287-95. PubMed ID: 19264848 [TBL] [Abstract][Full Text] [Related]
8. Molecular mechanisms of centipede toxin SsTx-4 inhibition of inwardly rectifying potassium channels. Tang D; Xu J; Li Y; Zhao P; Kong X; Hu H; Liang S; Tang C; Liu Z J Biol Chem; 2021 Sep; 297(3):101076. PubMed ID: 34391777 [TBL] [Abstract][Full Text] [Related]
9. Chloroquine blocks the Kir4.1 channels by an open-pore blocking mechanism. Marmolejo-Murillo LG; Aréchiga-Figueroa IA; Moreno-Galindo EG; Navarro-Polanco RA; Rodríguez-Menchaca AA; Cui M; Sánchez-Chapula JA; Ferrer T Eur J Pharmacol; 2017 Apr; 800():40-47. PubMed ID: 28216048 [TBL] [Abstract][Full Text] [Related]
10. Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590. Kharade SV; Sheehan JH; Figueroa EE; Meiler J; Denton JS Mol Pharmacol; 2017 Sep; 92(3):338-346. PubMed ID: 28619748 [TBL] [Abstract][Full Text] [Related]
11. [EAST/SeSAME syndrome and functional expression of inward rectifier potassium channel Kir4.1 in the inner ear]. Chen J; Zhao H Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2015 Jul; 29(14):1318-22. PubMed ID: 26672256 [TBL] [Abstract][Full Text] [Related]
12. Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133. Wang HR; Wu M; Yu H; Long S; Stevens A; Engers DW; Sackin H; Daniels JS; Dawson ES; Hopkins CR; Lindsley CW; Li M; McManus OB ACS Chem Biol; 2011 Aug; 6(8):845-56. PubMed ID: 21615117 [TBL] [Abstract][Full Text] [Related]
13. Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1. Raphemot R; Lonergan DF; Nguyen TT; Utley T; Lewis LM; Kadakia R; Weaver CD; Gogliotti R; Hopkins C; Lindsley CW; Denton JS Front Pharmacol; 2011; 2():75. PubMed ID: 22275899 [TBL] [Abstract][Full Text] [Related]
14. The role of an inwardly rectifying K(+) channel (Kir4.1) in the inner ear and hearing loss. Chen J; Zhao HB Neuroscience; 2014 Apr; 265():137-46. PubMed ID: 24480364 [TBL] [Abstract][Full Text] [Related]
15. High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1. Lewis LM; Bhave G; Chauder BA; Banerjee S; Lornsen KA; Redha R; Fallen K; Lindsley CW; Weaver CD; Denton JS Mol Pharmacol; 2009 Nov; 76(5):1094-103. PubMed ID: 19706730 [TBL] [Abstract][Full Text] [Related]