BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 29895863)

  • 1. Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic.
    Reddy JA; Dorton R; Bloomfield A; Nelson M; Dircksen C; Vetzel M; Kleindl P; Santhapuram H; Vlahov IR; Leamon CP
    Sci Rep; 2018 Jun; 8(1):8943. PubMed ID: 29895863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs.
    Reddy JA; Dorton R; Bloomfield A; Nelson M; Vetzel M; Guan J; Leamon CP
    Clin Cancer Res; 2014 Apr; 20(8):2104-14. PubMed ID: 24429878
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy.
    Leamon CP; Reddy JA; Vlahov IR; Dorton R; Bloomfield A; Vetzel M; Klein PJ; Westrick E; Xu LC; Wang Y
    Cancer Chemother Pharmacol; 2017 Jun; 79(6):1151-1160. PubMed ID: 28451831
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent.
    Reddy JA; Nelson M; Dircksen C; Vetzel M; Johnson T; Cross V; Westrick E; Qi L; Hahn S; Santhapuram HK; Parham G; Wang K; Vaughn JF; Felten A; Pugh M; Lu J; Klein P; Vlahov IR; Leamon CP
    Sci Rep; 2020 Jul; 10(1):12772. PubMed ID: 32728172
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development and validation of a UPLC-MS/MS method for the novel folate-targeted small molecule drug conjugate EC1456 and its metabolites in tumor homogenates from mice.
    Rao SI; Pugh M; Nelson M; Reddy JA; Klein PJ; Leamon CP
    J Pharm Biomed Anal; 2016 Apr; 122():148-56. PubMed ID: 26855286
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate.
    Leamon CP; Reddy JA; Bloomfield A; Dorton R; Nelson M; Vetzel M; Kleindl P; Hahn S; Wang K; Vlahov IR
    Bioconjug Chem; 2019 Jun; 30(6):1805-1813. PubMed ID: 31075200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preclinical antitumor activity of a novel folate-targeted dual drug conjugate.
    Leamon CP; Reddy JA; Vlahov IR; Westrick E; Dawson A; Dorton R; Vetzel M; Santhapuram HK; Wang Y
    Mol Pharm; 2007; 4(5):659-67. PubMed ID: 17874843
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Folate-vinca alkaloid conjugates for cancer therapy: a structure-activity relationship.
    Leamon CP; Vlahov IR; Reddy JA; Vetzel M; Santhapuram HK; You F; Bloomfield A; Dorton R; Nelson M; Kleindl P; Vaughn JF; Westrick E
    Bioconjug Chem; 2014 Mar; 25(3):560-8. PubMed ID: 24564229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo structural activity and optimization studies of folate-tubulysin conjugates.
    Reddy JA; Dorton R; Dawson A; Vetzel M; Parker N; Nicoson JS; Westrick E; Klein PJ; Wang Y; Vlahov IR; Leamon CP
    Mol Pharm; 2009; 6(5):1518-25. PubMed ID: 19630399
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue.
    Leamon CP; Reddy JA; Vetzel M; Dorton R; Westrick E; Parker N; Wang Y; Vlahov I
    Cancer Res; 2008 Dec; 68(23):9839-44. PubMed ID: 19047164
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.
    Reddy JA; Dorton R; Westrick E; Dawson A; Smith T; Xu LC; Vetzel M; Kleindl P; Vlahov IR; Leamon CP
    Cancer Res; 2007 May; 67(9):4434-42. PubMed ID: 17483358
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preclinical combination therapy of thiarabine plus various clinical anticancer agents.
    Waud WR; Gilbert KS; Secrist JA
    Nucleosides Nucleotides Nucleic Acids; 2012; 31(8):630-46. PubMed ID: 22908953
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
    Leamon CP; Reddy JA; Vlahov IR; Westrick E; Parker N; Nicoson JS; Vetzel M
    Int J Cancer; 2007 Oct; 121(7):1585-92. PubMed ID: 17551919
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention of carboplatin-induced resistance in human ovarian tumor xenografts by selenite.
    Caffrey PB; Frenkel GD
    Anticancer Res; 2013 Oct; 33(10):4249-54. PubMed ID: 24122988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nontoxic suramin treatments enhance docetaxel activity in chemotherapy-pretreated non-small cell lung xenograft tumors.
    Lu Z; Wientjes TS; Au JL
    Pharm Res; 2005 Jul; 22(7):1069-78. PubMed ID: 16028007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro and in vivo therapeutic efficacy of CXCR4 antagonist BKT140 against human non-small cell lung cancer.
    Fahham D; Weiss ID; Abraham M; Beider K; Hanna W; Shlomai Z; Eizenberg O; Zamir G; Izhar U; Shapira OM; Peled A; Wald O
    J Thorac Cardiovasc Surg; 2012 Nov; 144(5):1167-1175.e1. PubMed ID: 22925564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeted delivery of platinum-taxane combination therapy in ovarian cancer.
    Desale SS; Soni KS; Romanova S; Cohen SM; Bronich TK
    J Control Release; 2015 Dec; 220(Pt B):651-9. PubMed ID: 26381902
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Improved therapeutic activity of folate-targeted liposomal doxorubicin in folate receptor-expressing tumor models.
    Gabizon A; Tzemach D; Gorin J; Mak L; Amitay Y; Shmeeda H; Zalipsky S
    Cancer Chemother Pharmacol; 2010 May; 66(1):43-52. PubMed ID: 19779718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quinacrine in endometrial cancer: Repurposing an old antimalarial drug.
    Kalogera E; Roy D; Khurana A; Mondal S; Weaver AL; He X; Dowdy SC; Shridhar V
    Gynecol Oncol; 2017 Jul; 146(1):187-195. PubMed ID: 28545688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MEDI3617, a human anti-angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models.
    Leow CC; Coffman K; Inigo I; Breen S; Czapiga M; Soukharev S; Gingles N; Peterson N; Fazenbaker C; Woods R; Jallal B; Ricketts SA; Lavallee T; Coats S; Chang Y
    Int J Oncol; 2012 May; 40(5):1321-30. PubMed ID: 22327175
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.