137 related articles for article (PubMed ID: 29902720)
1. Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Zhu J; Zhou C; Caflisch A
Eur J Med Chem; 2018 Jul; 155():337-352. PubMed ID: 29902720
[TBL] [Abstract][Full Text] [Related]
2. Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain.
Lubula MY; Eckenroth BE; Carlson S; Poplawski A; Chruszcz M; Glass KC
FEBS Lett; 2014 Nov; 588(21):3844-54. PubMed ID: 25281266
[TBL] [Abstract][Full Text] [Related]
3. Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Palmer WS; Poncet-Montange G; Liu G; Petrocchi A; Reyna N; Subramanian G; Theroff J; Yau A; Kost-Alimova M; Bardenhagen JP; Leo E; Shepard HE; Tieu TN; Shi X; Zhan Y; Zhao S; Barton MC; Draetta G; Toniatti C; Jones P; Geck Do M; Andersen JN
J Med Chem; 2016 Feb; 59(4):1440-54. PubMed ID: 26061247
[TBL] [Abstract][Full Text] [Related]
4. Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
Zhu J; Caflisch A
J Med Chem; 2016 Jun; 59(11):5555-61. PubMed ID: 27167503
[TBL] [Abstract][Full Text] [Related]
5. Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.
Poplawski A; Hu K; Lee W; Natesan S; Peng D; Carlson S; Shi X; Balaz S; Markley JL; Glass KC
J Mol Biol; 2014 Apr; 426(8):1661-76. PubMed ID: 24333487
[TBL] [Abstract][Full Text] [Related]
6. Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9.
Gazzillo E; Pierri M; Colarusso E; Chini MG; Ferraro MG; Piccolo M; Irace C; Bruno I; Bifulco G; Terracciano S; Lauro G
Bioorg Chem; 2023 Oct; 139():106677. PubMed ID: 37352721
[TBL] [Abstract][Full Text] [Related]
7. Crystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands.
Lubula MY; Poplawaski A; Glass KC
Acta Crystallogr F Struct Biol Commun; 2014 Oct; 70(Pt 10):1389-93. PubMed ID: 25286946
[TBL] [Abstract][Full Text] [Related]
8. Integrated virtual screening and MD simulation approaches toward discovering potential inhibitors for targeting BRPF1 bromodomain in hepatocellular carcinoma.
Barman S; Bardhan I; Padhan J; Sudhamalla B
J Mol Graph Model; 2024 Jan; 126():108642. PubMed ID: 37797430
[TBL] [Abstract][Full Text] [Related]
9. Uncovering the non-histone interactome of the BRPF1 bromodomain using site-specific azide-acetyllysine photochemistry.
Barman S; Padhan J; Sudhamalla B
J Biol Chem; 2024 Jan; 300(1):105551. PubMed ID: 38072045
[TBL] [Abstract][Full Text] [Related]
10. Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors.
Xiang Q; Luo G; Zhang C; Hu Q; Wang C; Wu T; Xu H; Hu J; Zhuang X; Zhang M; Wu S; Xu J; Zhang Y; Liu J; Xu Y
Eur J Med Chem; 2022 Jun; 236():114311. PubMed ID: 35385803
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
Ghazy E; Zeyen P; Herp D; Hügle M; Schmidtkunz K; Erdmann F; Robaa D; Schmidt M; Morales ER; Romier C; Günther S; Jung M; Sippl W
Eur J Med Chem; 2020 Aug; 200():112338. PubMed ID: 32497960
[TBL] [Abstract][Full Text] [Related]
12. Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor.
Hu J; Wang Y; Li Y; Xu L; Cao D; Song S; Damaneh MS; Wang X; Meng T; Chen YL; Shen J; Miao Z; Xiong B
Eur J Med Chem; 2017 Sep; 137():176-195. PubMed ID: 28586718
[TBL] [Abstract][Full Text] [Related]
13. Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.
Law RP; Atkinson SJ; Bamborough P; Chung CW; Demont EH; Gordon LJ; Lindon M; Prinjha RK; Watson AJB; Hirst DJ
J Med Chem; 2018 May; 61(10):4317-4334. PubMed ID: 29656650
[TBL] [Abstract][Full Text] [Related]
14. Development of small molecule inhibitors of BRPF1 and TRIM24 bromodomains.
Palmer WS
Drug Discov Today Technol; 2016 Mar; 19():65-71. PubMed ID: 27769360
[TBL] [Abstract][Full Text] [Related]
15. Discovery of BAZ2A bromodomain ligands.
Spiliotopoulos D; Wamhoff EC; Lolli G; Rademacher C; Caflisch A
Eur J Med Chem; 2017 Oct; 139():564-572. PubMed ID: 28837921
[TBL] [Abstract][Full Text] [Related]
16. Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer.
Cheng CL; Tsang FH; Wei L; Chen M; Chin DW; Shen J; Law CT; Lee D; Wong CC; Ng IO; Wong CM
Commun Biol; 2021 Jul; 4(1):888. PubMed ID: 34285329
[TBL] [Abstract][Full Text] [Related]
17. Computational studies with flavonoids and terpenoids as BRPF1 inhibitors: in silico biological activity prediction, molecular docking, molecular dynamics simulations, MM/PBSA calculations.
Yalçin-Özkat G
SAR QSAR Environ Res; 2022 Jul; 33(7):533-550. PubMed ID: 35822928
[TBL] [Abstract][Full Text] [Related]
18. Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Bennett J; Fedorov O; Tallant C; Monteiro O; Meier J; Gamble V; Savitsky P; Nunez-Alonso GA; Haendler B; Rogers C; Brennan PE; Müller S; Knapp S
J Med Chem; 2016 Feb; 59(4):1642-7. PubMed ID: 25974391
[TBL] [Abstract][Full Text] [Related]
19. The BRPF1 bromodomain is a molecular reader of di-acetyllysine.
Obi JO; Lubula MY; Cornilescu G; Henrickson A; McGuire K; Evans CM; Phillips M; Boyson SP; Demeler B; Markley JL; Glass KC
Curr Res Struct Biol; 2020; 2():104-115. PubMed ID: 33554132
[TBL] [Abstract][Full Text] [Related]
20. Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
Duffy BC; Liu S; Martin GS; Wang R; Hsia MM; Zhao H; Guo C; Ellis M; Quinn JF; Kharenko OA; Norek K; Gesner EM; Young PR; McLure KG; Wagner GS; Lakshminarasimhan D; White A; Suto RK; Hansen HC; Kitchen DB
Bioorg Med Chem Lett; 2015 Jul; 25(14):2818-23. PubMed ID: 26022843
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]