These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
23. Inhibition of Escherichia coli ribosome subunit dissociation by chloramphenicol and Blasticidin: a new mode of action of the antibiotics. Pathak BK; Mondal S; Barat C Lett Appl Microbiol; 2017 Jan; 64(1):79-85. PubMed ID: 27739094 [TBL] [Abstract][Full Text] [Related]
24. The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation. Zhang Y; Aleksashin NA; Klepacki D; Anderson C; Vázquez-Laslop N; Gross CA; Mankin AS Proc Natl Acad Sci U S A; 2022 Jan; 119(4):. PubMed ID: 35064089 [TBL] [Abstract][Full Text] [Related]
25. Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Tsai K; Stojković V; Lee DJ; Young ID; Szal T; Klepacki D; Vázquez-Laslop N; Mankin AS; Fraser JS; Fujimori DG Nat Struct Mol Biol; 2022 Feb; 29(2):162-171. PubMed ID: 35165456 [TBL] [Abstract][Full Text] [Related]
26. trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Aron ZD; Mehrani A; Hoffer ED; Connolly KL; Srinivas P; Torhan MC; Alumasa JN; Cabrera M; Hosangadi D; Barbor JS; Cardinale SC; Kwasny SM; Morin LR; Butler MM; Opperman TJ; Bowlin TL; Jerse A; Stagg SM; Dunham CM; Keiler KC Nat Commun; 2021 Mar; 12(1):1799. PubMed ID: 33741965 [TBL] [Abstract][Full Text] [Related]
27. Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. Harms JM; Schlünzen F; Fucini P; Bartels H; Yonath A BMC Biol; 2004 Apr; 2():4. PubMed ID: 15059283 [TBL] [Abstract][Full Text] [Related]
28. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Osterman IA; Khabibullina NF; Komarova ES; Kasatsky P; Kartsev VG; Bogdanov AA; Dontsova OA; Konevega AL; Sergiev PV; Polikanov YS Nucleic Acids Res; 2017 Jul; 45(12):7507-7514. PubMed ID: 28505372 [TBL] [Abstract][Full Text] [Related]
29. Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome. Kirillov SV; Porse BT; Garrett RA RNA; 1999 Aug; 5(8):1003-13. PubMed ID: 10445875 [TBL] [Abstract][Full Text] [Related]
30. Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Beckert B; Leroy EC; Sothiselvam S; Bock LV; Svetlov MS; Graf M; Arenz S; Abdelshahid M; Seip B; Grubmüller H; Mankin AS; Innis CA; Vázquez-Laslop N; Wilson DN Nat Commun; 2021 Jul; 12(1):4466. PubMed ID: 34294725 [TBL] [Abstract][Full Text] [Related]
32. Antimicrobial agents targeting the ribosome: the issue of selectivity and toxicity - lessons to be learned. Böttger EC Cell Mol Life Sci; 2007 Apr; 64(7-8):791-5. PubMed ID: 17429579 [No Abstract] [Full Text] [Related]
33. Ribosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coli. Holberger LE; Hayes CS J Biol Chem; 2009 Nov; 284(46):32188-200. PubMed ID: 19776006 [TBL] [Abstract][Full Text] [Related]
34. Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Llano-Sotelo B; Dunkle J; Klepacki D; Zhang W; Fernandes P; Cate JH; Mankin AS Antimicrob Agents Chemother; 2010 Dec; 54(12):4961-70. PubMed ID: 20855725 [TBL] [Abstract][Full Text] [Related]
35. Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides. Khabibullina NF; Tereshchenkov AG; Komarova ES; Syroegin EA; Shiriaev DI; Paleskava A; Kartsev VG; Bogdanov AA; Konevega AL; Dontsova OA; Sergiev PV; Osterman IA; Polikanov YS Antimicrob Agents Chemother; 2019 Jun; 63(6):. PubMed ID: 30936109 [TBL] [Abstract][Full Text] [Related]
36. Erythromycin- and chloramphenicol-induced ribosomal assembly defects are secondary effects of protein synthesis inhibition. Siibak T; Peil L; Xiong L; Mankin A; Remme J; Tenson T Antimicrob Agents Chemother; 2009 Feb; 53(2):563-71. PubMed ID: 19029332 [TBL] [Abstract][Full Text] [Related]
37. Impact of P-Site tRNA and antibiotics on ribosome mediated protein folding: studies using the Escherichia coli ribosome. Mondal S; Pathak BK; Ray S; Barat C PLoS One; 2014; 9(7):e101293. PubMed ID: 25000563 [TBL] [Abstract][Full Text] [Related]
38. Antibiotics and the ribosome. Tenson T; Mankin A Mol Microbiol; 2006 Mar; 59(6):1664-77. PubMed ID: 16553874 [TBL] [Abstract][Full Text] [Related]
39. Tools for characterizing bacterial protein synthesis inhibitors. Orelle C; Carlson S; Kaushal B; Almutairi MM; Liu H; Ochabowicz A; Quan S; Pham VC; Squires CL; Murphy BT; Mankin AS Antimicrob Agents Chemother; 2013 Dec; 57(12):5994-6004. PubMed ID: 24041905 [TBL] [Abstract][Full Text] [Related]
40. Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the Pichkur EB; Paleskava A; Tereshchenkov AG; Kasatsky P; Komarova ES; Shiriaev DI; Bogdanov AA; Dontsova OA; Osterman IA; Sergiev PV; Polikanov YS; Myasnikov AG; Konevega AL RNA; 2020 Jun; 26(6):715-723. PubMed ID: 32144191 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]