356 related articles for article (PubMed ID: 29909971)
1. Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain.
Lin G; Lee PT; Chen K; Mao D; Tan KL; Zuo Z; Lin WW; Wang L; Bellen HJ
Cell Metab; 2018 Oct; 28(4):605-618.e6. PubMed ID: 29909971
[TBL] [Abstract][Full Text] [Related]
2. Parkinson's disease-associated
Mori A; Hatano T; Inoshita T; Shiba-Fukushima K; Koinuma T; Meng H; Kubo SI; Spratt S; Cui C; Yamashita C; Miki Y; Yamamoto K; Hirabayashi T; Murakami M; Takahashi Y; Shindou H; Nonaka T; Hasegawa M; Okuzumi A; Imai Y; Hattori N
Proc Natl Acad Sci U S A; 2019 Oct; 116(41):20689-20699. PubMed ID: 31548400
[TBL] [Abstract][Full Text] [Related]
3. Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction.
Kinghorn KJ; Castillo-Quan JI; Bartolome F; Angelova PR; Li L; Pope S; Cochemé HM; Khan S; Asghari S; Bhatia KP; Hardy J; Abramov AY; Partridge L
Brain; 2015 Jul; 138(Pt 7):1801-16. PubMed ID: 26001724
[TBL] [Abstract][Full Text] [Related]
4. Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14).
Lin G; Tepe B; McGrane G; Tipon RC; Croft G; Panwala L; Hope A; Liang AJH; Zuo Z; Byeon SK; Wang L; Pandey A; Bellen HJ
Elife; 2023 Jan; 12():. PubMed ID: 36645408
[TBL] [Abstract][Full Text] [Related]
5. Sphingolipids in the Pathogenesis of Parkinson's Disease and Parkinsonism.
Lin G; Wang L; Marcogliese PC; Bellen HJ
Trends Endocrinol Metab; 2019 Feb; 30(2):106-117. PubMed ID: 30528460
[TBL] [Abstract][Full Text] [Related]
6. VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease.
Miura E; Hasegawa T; Konno M; Suzuki M; Sugeno N; Fujikake N; Geisler S; Tabuchi M; Oshima R; Kikuchi A; Baba T; Wada K; Nagai Y; Takeda A; Aoki M
Neurobiol Dis; 2014 Nov; 71():1-13. PubMed ID: 25107340
[TBL] [Abstract][Full Text] [Related]
7. Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism.
Engel LA; Jing Z; O'Brien DE; Sun M; Kotzbauer PT
PLoS One; 2010 Sep; 5(9):e12897. PubMed ID: 20886109
[TBL] [Abstract][Full Text] [Related]
8. Mutations in the Drosophila homolog of human PLA2G6 give rise to age-dependent loss of psychomotor activity and neurodegeneration.
Iliadi KG; Gluscencova OB; Iliadi N; Boulianne GL
Sci Rep; 2018 Feb; 8(1):2939. PubMed ID: 29440694
[TBL] [Abstract][Full Text] [Related]
9. VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson's disease.
Chen X; Tsika E; Levine N; Moore DJ
Mol Neurodegener; 2023 Aug; 18(1):51. PubMed ID: 37542299
[TBL] [Abstract][Full Text] [Related]
10. Neuroaxonal dystrophy in PLA2G6 knockout mice.
Sumi-Akamaru H; Beck G; Kato S; Mochizuki H
Neuropathology; 2015 Jun; 35(3):289-302. PubMed ID: 25950622
[TBL] [Abstract][Full Text] [Related]
11. Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation.
Follett J; Bugarcic A; Yang Z; Ariotti N; Norwood SJ; Collins BM; Parton RG; Teasdale RD
J Biol Chem; 2016 Aug; 291(35):18283-98. PubMed ID: 27385586
[TBL] [Abstract][Full Text] [Related]
12. Neurons and astrocytes in an infantile neuroaxonal dystrophy (INAD) mouse model show characteristic alterations in glutamate-induced Ca
Strokin M; Reiser G
Neurochem Int; 2017 Sep; 108():121-132. PubMed ID: 28279750
[TBL] [Abstract][Full Text] [Related]
13. High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction.
Sumi-Akamaru H; Beck G; Shinzawa K; Kato S; Riku Y; Yoshida M; Fujimura H; Tsujimoto Y; Sakoda S; Mochizuki H
Acta Neuropathol Commun; 2016 Mar; 4():27. PubMed ID: 27030050
[TBL] [Abstract][Full Text] [Related]
14. Mitochondria from a mouse model of the human infantile neuroaxonal dystrophy (INAD) with genetic defects in VIA iPLA2 have disturbed Ca(2+) regulation with reduction in Ca(2+) capacity.
Strokin M; Reiser G
Neurochem Int; 2016 Oct; 99():187-193. PubMed ID: 27395788
[TBL] [Abstract][Full Text] [Related]
15. Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain.
Ye H; Ojelade SA; Li-Kroeger D; Zuo Z; Wang L; Li Y; Gu JY; Tepass U; Rodal AA; Bellen HJ; Shulman JM
Elife; 2020 Apr; 9():. PubMed ID: 32286230
[TBL] [Abstract][Full Text] [Related]
16. A new PLA2G6 mutation in a family with infantile neuroaxonal dystrophy.
Iannello G; Graziano C; Cenacchi G; Cordelli DM; Zuntini R; Papa V; Magistà AM; Gagliardi M; Procopio R; Quattrone A; Annesi G
J Neurol Sci; 2017 Oct; 381():209-212. PubMed ID: 28991683
[TBL] [Abstract][Full Text] [Related]
17. VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.
Tang FL; Erion JR; Tian Y; Liu W; Yin DM; Ye J; Tang B; Mei L; Xiong WC
J Neurosci; 2015 Jul; 35(29):10613-28. PubMed ID: 26203154
[TBL] [Abstract][Full Text] [Related]
18. An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex.
Macías-Calvio V; Fuentealba LM; Marzolo MP
J Neurosci Res; 2021 Jan; 99(1):163-179. PubMed ID: 32633426
[TBL] [Abstract][Full Text] [Related]
19. The role of the PLA2G6 gene in neurodegenerative diseases.
Deng X; Yuan L; Jankovic J; Deng H
Ageing Res Rev; 2023 Aug; 89():101957. PubMed ID: 37236368
[TBL] [Abstract][Full Text] [Related]
20. Extensive aggregation of α-synuclein and tau in juvenile-onset neuroaxonal dystrophy: an autopsied individual with a novel mutation in the PLA2G6 gene-splicing site.
Riku Y; Ikeuchi T; Yoshino H; Mimuro M; Mano K; Goto Y; Hattori N; Sobue G; Yoshida M
Acta Neuropathol Commun; 2013 May; 1():12. PubMed ID: 24252552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]