BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 29913682)

  • 1. GCH1 variants, tetrahydrobiopterin and their effects on pain sensitivity.
    Nasser A; Møller LB
    Scand J Pain; 2014 Apr; 5(2):121-128. PubMed ID: 29913682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.
    Nasser A; Bjerrum OJ; Heegaard AM; Møller AT; Larsen M; Dalbøge LS; Dupont E; Jensen TS; Møller LB
    Mol Pain; 2013 Feb; 9():5. PubMed ID: 23421753
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of GTP cyclohydrolase reduces cancer pain in mice and enhances analgesic effects of morphine.
    Pickert G; Myrczek T; Rückert S; Weigert A; Häussler A; Ferreirós N; Brüne B; Lötsch J; Tegeder I
    J Mol Med (Berl); 2012 Dec; 90(12):1473-86. PubMed ID: 22706600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
    Tegeder I; Costigan M; Griffin RS; Abele A; Belfer I; Schmidt H; Ehnert C; Nejim J; Marian C; Scholz J; Wu T; Allchorne A; Diatchenko L; Binshtok AM; Goldman D; Adolph J; Sama S; Atlas SJ; Carlezon WA; Parsegian A; Lötsch J; Fillingim RB; Maixner W; Geisslinger G; Max MB; Woolf CJ
    Nat Med; 2006 Nov; 12(11):1269-77. PubMed ID: 17057711
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity.
    Nasser A; Møller AT; Hellmund V; Thorborg SS; Jespersgaard C; Bjerrum OJ; Dupont E; Nachman G; Lykkesfeldt J; Jensen TS; Møller LB
    Pain; 2018 Jun; 159(6):1012-1024. PubMed ID: 29470312
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype.
    Tegeder I; Adolph J; Schmidt H; Woolf CJ; Geisslinger G; Lötsch J
    Eur J Pain; 2008 Nov; 12(8):1069-77. PubMed ID: 18374612
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular genetics of dopa-responsive dystonia.
    Ichinose H; Suzuki T; Inagaki H; Ohye T; Nagatsu T
    Biol Chem; 1999 Dec; 380(12):1355-64. PubMed ID: 10661862
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Dopa-responsive dystonia: clinical, genetic, and biochemical studies].
    Furukawa Y
    Rinsho Shinkeigaku; 2006 Jan; 46(1):19-34. PubMed ID: 16541791
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mast cell tetrahydrobiopterin contributes to itch in mice.
    Zschiebsch K; Fischer C; Wilken-Schmitz A; Geisslinger G; Channon K; Watschinger K; Tegeder I
    J Cell Mol Med; 2019 Feb; 23(2):985-1000. PubMed ID: 30450838
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
    Adlam D; Herring N; Douglas G; De Bono JP; Li D; Danson EJ; Tatham A; Lu CJ; Jennings KA; Cragg SJ; Casadei B; Paterson DJ; Channon KM
    Cardiovasc Res; 2012 Mar; 93(4):694-701. PubMed ID: 22241166
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk.
    Doehring A; Antoniades C; Channon KM; Tegeder I; Lötsch J
    Mutat Res; 2008; 659(3):195-201. PubMed ID: 18515178
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms underlying the efficacy and limitation of dopa and tetrahydrobiopterin therapies for the deficiency of GTP cyclohydrolase 1 revealed in a novel mouse model.
    Jiang X; Shao Y; Liao Y; Zheng X; Peng M; Cai Y; Wang M; Liu H; Zeng C; Lin Y; Zhang W; Liu L
    Eur J Pharmacol; 2024 Mar; 967():176379. PubMed ID: 38342361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catecholamines and Parkinson's disease: tyrosine hydroxylase (TH) over tetrahydrobiopterin (BH4) and GTP cyclohydrolase I (GCH1) to cytokines, neuromelanin, and gene therapy: a historical overview.
    Nagatsu T
    J Neural Transm (Vienna); 2023 Aug; ():. PubMed ID: 37638996
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer.
    Cronin SJF; Rao S; Tejada MA; Turnes BL; Licht-Mayer S; Omura T; Brenneis C; Jacobs E; Barrett L; Latremoliere A; Andrews N; Channon KM; Latini A; Arvanites AC; Davidow LS; Costigan M; Rubin LL; Penninger JM; Woolf CJ
    Sci Transl Med; 2022 Aug; 14(660):eabj1531. PubMed ID: 36044597
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced lymphoblast neopterin detects GTP cyclohydrolase dysfunction in dopa-responsive dystonia.
    Bezin L; Nygaard TG; Neville JD; Shen H; Levine RA
    Neurology; 1998 Apr; 50(4):1021-7. PubMed ID: 9566389
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A requirement for Gch1 and tetrahydrobiopterin in embryonic development.
    Douglas G; Hale AB; Crabtree MJ; Ryan BJ; Hansler A; Watschinger K; Gross SS; Lygate CA; Alp NJ; Channon KM
    Dev Biol; 2015 Mar; 399(1):129-138. PubMed ID: 25557619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GCH1, BH4 and pain.
    Latremoliere A; Costigan M
    Curr Pharm Biotechnol; 2011 Oct; 12(10):1728-41. PubMed ID: 21466440
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combining Human and Rodent Genetics to Identify New Analgesics.
    Latremoliere A; Costigan M
    Neurosci Bull; 2018 Feb; 34(1):143-155. PubMed ID: 28667479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intraplantar injection of tetrahydrobiopterin induces nociception in mice.
    Nasser A; Ali S; Wilsbech S; Bjerrum OJ; Møller LB
    Neurosci Lett; 2015 Jan; 584():247-52. PubMed ID: 25450138
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GTP cyclohydroxylase1 (GCH1): Role in neurodegenerative diseases.
    Gupta P; Kumar R
    Gene; 2023 Dec; 888():147749. PubMed ID: 37652170
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.