BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 29915999)

  • 1. Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
    Xiao G; Rowbottom C; Boiselle C; Gan LS
    Pharm Res; 2018 Jun; 35(8):159. PubMed ID: 29915999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin.
    Sauzay C; White-Koning M; Hennebelle I; Deluche T; Delmas C; Imbs DC; Chatelut E; Thomas F
    Pharmacol Res; 2016 Aug; 110():89-95. PubMed ID: 27178732
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine.
    Müller F; Weitz D; Derdau V; Sandvoss M; Mertsch K; König J; Fromm MF
    Mol Pharm; 2017 Sep; 14(9):2991-2998. PubMed ID: 28708400
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine.
    Müller F; König J; Hoier E; Mandery K; Fromm MF
    Biochem Pharmacol; 2013 Sep; 86(6):808-15. PubMed ID: 23876341
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.
    van der Velden M; Bilos A; van den Heuvel JJMW; Rijpma SR; Hurkmans EGE; Sauerwein RW; Russel FGM; Koenderink JB
    Malar J; 2017 Oct; 16(1):422. PubMed ID: 29061131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).
    Kikuchi R; Lao Y; Bow DA; Chiou WJ; Andracki ME; Carr RA; Voorman RL; De Morais SM
    J Pharm Sci; 2013 Dec; 102(12):4426-32. PubMed ID: 24122511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Importance of OCT2 and MATE1 for the Cimetidine-Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition.
    Müller F; Weitz D; Mertsch K; König J; Fromm MF
    Mol Pharm; 2018 Aug; 15(8):3425-3433. PubMed ID: 29975542
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects.
    Topletz-Erickson AR; Lee AJ; Mayor JG; Rustia EL; Abdulrasool LI; Wise AL; Dailey B; DeChenne S; Walker LN; Alley SC; Endres CJ
    J Clin Pharmacol; 2021 Apr; 61(4):461-471. PubMed ID: 32989831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.
    Te Brake LH; van den Heuvel JJ; Buaben AO; van Crevel R; Bilos A; Russel FG; Aarnoutse RE; Koenderink JB
    Antimicrob Agents Chemother; 2016 Dec; 60(12):7105-7114. PubMed ID: 27645247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
    Ito S; Kusuhara H; Yokochi M; Toyoshima J; Inoue K; Yuasa H; Sugiyama Y
    J Pharmacol Exp Ther; 2012 Feb; 340(2):393-403. PubMed ID: 22072731
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
    Misaka S; Knop J; Singer K; Hoier E; Keiser M; Müller F; Glaeser H; König J; Fromm MF
    Mol Pharm; 2016 Feb; 13(2):512-9. PubMed ID: 26702643
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs.
    George B; Wen X; Jaimes EA; Joy MS; Aleksunes LM
    Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34208557
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium.
    Deutsch B; Neumeister C; Schwantes U; Fromm MF; König J
    Mol Pharm; 2019 Feb; 16(2):510-517. PubMed ID: 30656943
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of vandetanib as an inhibitor of various human renal transporters: inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance.
    Shen H; Yang Z; Zhao W; Zhang Y; Rodrigues AD
    Drug Metab Dispos; 2013 Dec; 41(12):2095-103. PubMed ID: 24026623
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins.
    Shen H; Yao M; Sinz M; Marathe P; Rodrigues AD; Zhu M
    Mol Pharm; 2019 Sep; 16(9):4065-4076. PubMed ID: 31335150
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.
    König J; Zolk O; Singer K; Hoffmann C; Fromm MF
    Br J Pharmacol; 2011 Jun; 163(3):546-55. PubMed ID: 20883471
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pregnancy Increases the Renal Secretion of N
    Bergagnini-Kolev MC; Hebert MF; Easterling TR; Lin YS
    Drug Metab Dispos; 2017 Mar; 45(3):325-329. PubMed ID: 28069720
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
    Knop J; Misaka S; Singer K; Hoier E; Müller F; Glaeser H; König J; Fromm MF
    PLoS One; 2015; 10(10):e0139370. PubMed ID: 26426900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
    Nishizawa K; Yoda N; Morokado F; Komori H; Nakanishi T; Tamai I
    PLoS One; 2019; 14(4):e0214862. PubMed ID: 30951542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanism of renal tubular secretion of the antimalarial drug chloroquine.
    Müller F; König J; Glaeser H; Schmidt I; Zolk O; Fromm MF; Maas R
    Antimicrob Agents Chemother; 2011 Jul; 55(7):3091-8. PubMed ID: 21518836
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.