These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma. Zaretsky JM; Garcia-Diaz A; Shin DS; Escuin-Ordinas H; Hugo W; Hu-Lieskovan S; Torrejon DY; Abril-Rodriguez G; Sandoval S; Barthly L; Saco J; Homet Moreno B; Mezzadra R; Chmielowski B; Ruchalski K; Shintaku IP; Sanchez PJ; Puig-Saus C; Cherry G; Seja E; Kong X; Pang J; Berent-Maoz B; Comin-Anduix B; Graeber TG; Tumeh PC; Schumacher TN; Lo RS; Ribas A N Engl J Med; 2016 Sep; 375(9):819-29. PubMed ID: 27433843 [TBL] [Abstract][Full Text] [Related]
4. JAK2, PD-L1, and PD-L2 (9p24.1) amplification in metastatic mucosal and cutaneous melanomas with durable response to immunotherapy. Gupta S; Vanderbilt CM; Cotzia P; Arias Stella JA; Chang JC; Chen Y; Tang LH; DeLair DF; Yao J; Ladanyi M; Ross DS Hum Pathol; 2019 Jun; 88():87-91. PubMed ID: 30236595 [TBL] [Abstract][Full Text] [Related]
5. Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications. Li SD; Ma M; Li H; Waluszko A; Sidorenko T; Schadt EE; Zhang DY; Chen R; Ye F Genome Med; 2017 Oct; 9(1):89. PubMed ID: 29082853 [TBL] [Abstract][Full Text] [Related]
6. Differences in global gene expression in melanoma cell lines with and without homozygous deletion of the CDKN2A locus genes. Bloethner S; Hemminki K; Thirumaran RK; Chen B; Mueller-Berghaus J; Ugurel S; Schadendorf D; Kumar R Melanoma Res; 2006 Aug; 16(4):297-307. PubMed ID: 16845325 [TBL] [Abstract][Full Text] [Related]
7. Mutation patterns in genes encoding interferon signaling and antigen presentation: A pan-cancer survey with implications for the use of immune checkpoint inhibitors. Budczies J; Bockmayr M; Klauschen F; Endris V; Fröhling S; Schirmacher P; Denkert C; Stenzinger A Genes Chromosomes Cancer; 2017 Aug; 56(8):651-659. PubMed ID: 28466543 [TBL] [Abstract][Full Text] [Related]
8. Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma. Tsao H; Zhang X; Kwitkiwski K; Finkelstein DM; Sober AJ; Haluska FG Arch Dermatol; 2000 Sep; 136(9):1118-22. PubMed ID: 10987867 [TBL] [Abstract][Full Text] [Related]
9. Assessment of clinical outcomes with immune checkpoint inhibitor therapy in melanoma patients with CDKN2A and TP53 pathogenic mutations. DeLeon TT; Almquist DR; Kipp BR; Langlais BT; Mangold A; Winters JL; Kosiorek HE; Joseph RW; Dronca RS; Block MS; McWilliams RR; Kottschade LA; Rumilla KM; Voss JS; Seetharam M; Sekulic A; Markovic SN; Bryce AH PLoS One; 2020; 15(3):e0230306. PubMed ID: 32196516 [TBL] [Abstract][Full Text] [Related]
11. Efficacy of novel immunotherapy regimens in patients with metastatic melanoma with germline Helgadottir H; Ghiorzo P; van Doorn R; Puig S; Levin M; Kefford R; Lauss M; Queirolo P; Pastorino L; Kapiteijn E; Potrony M; Carrera C; Olsson H; Höiom V; Jönsson G J Med Genet; 2020 May; 57(5):316-321. PubMed ID: 30291219 [TBL] [Abstract][Full Text] [Related]
12. CDKN2A germ-line mutations in individuals with multiple cutaneous melanomas. Hashemi J; Platz A; Ueno T; Stierner U; Ringborg U; Hansson J Cancer Res; 2000 Dec; 60(24):6864-7. PubMed ID: 11156381 [TBL] [Abstract][Full Text] [Related]
13. Genomic rearrangements of the CDKN2A locus are infrequent in Italian malignant melanoma families without evidence of CDKN2A/CDK4 point mutations. Vignoli M; Scaini MC; Ghiorzo P; Sestini R; Bruno W; Menin C; Gensini F; Piazzini M; Testori A; Manoukian S; Orlando C; D'Andrea E; Bianchi-Scarrà G; Genuardi M Melanoma Res; 2008 Dec; 18(6):431-7. PubMed ID: 19011513 [TBL] [Abstract][Full Text] [Related]
14. Genetic status of cell cycle regulators in squamous cell carcinoma of the oesophagus: the CDKN2A (p16(INK4a) and p14(ARF) ) and p53 genes are major targets for inactivation. Smeds J; Berggren P; Ma X; Xu Z; Hemminki K; Kumar R Carcinogenesis; 2002 Apr; 23(4):645-55. PubMed ID: 11960918 [TBL] [Abstract][Full Text] [Related]
15. CDKN2A and CDK4 variants in Latvian melanoma patients: analysis of a clinic-based population. Pjanova D; Engele L; Randerson-Moor JA; Harland M; Bishop DT; Newton Bishop JA; Taylor C; Debniak T; Lubinski J; Kleina R; Heisele O Melanoma Res; 2007 Jun; 17(3):185-91. PubMed ID: 17505264 [TBL] [Abstract][Full Text] [Related]
16. Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B. Soto JL; Cabrera CM; Serrano S; López-Nevot MA BMC Cancer; 2005 Apr; 5():36. PubMed ID: 15819981 [TBL] [Abstract][Full Text] [Related]
17. CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation. Della Torre G; Pasini B; Frigerio S; Donghi R; Rovini D; Delia D; Peters G; Huot TJ; Bianchi-Scarra G; Lantieri F; Rodolfo M; Parmiani G; Pierotti MA Br J Cancer; 2001 Sep; 85(6):836-44. PubMed ID: 11556834 [TBL] [Abstract][Full Text] [Related]
18. CDKN2A as a uveal and cutaneous melanoma susceptibility gene. Kannengiesser C; Avril MF; Spatz A; Laud K; Lenoir GM; Bressac-de-Paillerets B Genes Chromosomes Cancer; 2003 Nov; 38(3):265-8. PubMed ID: 14506702 [TBL] [Abstract][Full Text] [Related]
19. [From gene to disease; from p16 to melanoma]. Gruis NA; Bergman W Ned Tijdschr Geneeskd; 2000 Oct; 144(44):2100-2. PubMed ID: 11103670 [TBL] [Abstract][Full Text] [Related]
20. CDKN2a mutation-negative melanoma families have increased risk exclusively for skin cancers but not for other malignancies. Helgadottir H; Höiom V; Tuominen R; Jönsson G; Månsson-Brahme E; Olsson H; Hansson J Int J Cancer; 2015 Nov; 137(9):2220-6. PubMed ID: 25943250 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]