BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 29925347)

  • 1. WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.
    Neilsen BK; Chakraborty B; McCall JL; Frodyma DE; Sleightholm RL; Fisher KW; Lewis RE
    BMC Cancer; 2018 Jun; 18(1):673. PubMed ID: 29925347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting WD repeat domain 5 enhances chemosensitivity and inhibits proliferation and programmed death-ligand 1 expression in bladder cancer.
    Zhang J; Zhou Q; Xie K; Cheng L; Peng S; Xie R; Liu L; Zhang Y; Dong W; Han J; Huang M; Chen Y; Lin T; Huang J; Chen X
    J Exp Clin Cancer Res; 2021 Jun; 40(1):203. PubMed ID: 34154613
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer.
    Kim JY; Banerjee T; Vinckevicius A; Luo Q; Parker JB; Baker MR; Radhakrishnan I; Wei JJ; Barish GD; Chakravarti D
    Mol Cell; 2014 May; 54(4):613-25. PubMed ID: 24793694
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.
    Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JW; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T
    Cancer Res; 2015 Dec; 75(23):5143-54. PubMed ID: 26471359
    [TBL] [Abstract][Full Text] [Related]  

  • 5. WDR5 in porcine preimplantation embryos: expression, regulation of epigenetic modifications and requirement for early development†.
    Ding B; Cao Z; Hong R; Li H; Zuo X; Luo L; Li Y; Huang W; Li W; Zhang K; Zhang Y
    Biol Reprod; 2017 Apr; 96(4):758-771. PubMed ID: 28379447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Histone H3 Lysine 4 Presenter WDR5 as an Oncogenic Protein and Novel Epigenetic Target in Cancer.
    Lu K; Tao H; Si X; Chen Q
    Front Oncol; 2018; 8():502. PubMed ID: 30488017
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.
    Carugo A; Genovese G; Seth S; Nezi L; Rose JL; Bossi D; Cicalese A; Shah PK; Viale A; Pettazzoni PF; Akdemir KC; Bristow CA; Robinson FS; Tepper J; Sanchez N; Gupta S; Estecio MR; Giuliani V; Dellino GI; Riva L; Yao W; Di Francesco ME; Green T; D'Alesio C; Corti D; Kang Y; Jones P; Wang H; Fleming JB; Maitra A; Pelicci PG; Chin L; DePinho RA; Lanfrancone L; Heffernan TP; Draetta GF
    Cell Rep; 2016 Jun; 16(1):133-147. PubMed ID: 27320920
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.
    Bochyńska A; Lüscher-Firzlaff J; Lüscher B
    Cells; 2018 Mar; 7(3):. PubMed ID: 29498679
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16
    Shimoda H; Doi S; Nakashima A; Sasaki K; Doi T; Masaki T
    Kidney Int; 2019 Nov; 96(5):1162-1175. PubMed ID: 31570196
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.
    Guccione E; Bassi C; Casadio F; Martinato F; Cesaroni M; Schuchlautz H; Lüscher B; Amati B
    Nature; 2007 Oct; 449(7164):933-7. PubMed ID: 17898714
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Up-regulated WDR5 promotes gastric cancer formation by induced cyclin D1 expression.
    Sun W; Guo F; Liu M
    J Cell Biochem; 2018 Apr; 119(4):3304-3316. PubMed ID: 29125890
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells.
    Chen J; Ding J; Wang Z; Zhu J; Wang X; Du J
    Oncotarget; 2017 Mar; 8(12):19609-19630. PubMed ID: 28121627
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.
    Cai WL; Chen JF; Chen H; Wingrove E; Kurley SJ; Chan LH; Zhang M; Arnal-Estape A; Zhao M; Balabaki A; Li W; Yu X; Krop ED; Dou Y; Liu Y; Jin J; Westbrook TF; Nguyen DX; Yan Q
    Elife; 2022 Aug; 11():. PubMed ID: 36043466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.
    Chen X; Xie W; Gu P; Cai Q; Wang B; Xie Y; Dong W; He W; Zhong G; Lin T; Huang J
    Sci Rep; 2015 Feb; 5():8293. PubMed ID: 25656485
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
    Senisterra G; Wu H; Allali-Hassani A; Wasney GA; Barsyte-Lovejoy D; Dombrovski L; Dong A; Nguyen KT; Smil D; Bolshan Y; Hajian T; He H; Seitova A; Chau I; Li F; Poda G; Couture JF; Brown PJ; Al-Awar R; Schapira M; Arrowsmith CH; Vedadi M
    Biochem J; 2013 Jan; 449(1):151-9. PubMed ID: 22989411
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WDR5 high expression and its effect on tumorigenesis in leukemia.
    Ge Z; Song EJ; Kawasawa YI; Li J; Dovat S; Song C
    Oncotarget; 2016 Jun; 7(25):37740-37754. PubMed ID: 27192115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes.
    Kwon M; Park K; Hyun K; Lee JH; Zhou L; Cho YW; Ge K; Skalnik DG; Muir TW; Kim J
    Nucleic Acids Res; 2020 Jun; 48(10):5442-5456. PubMed ID: 32365172
    [TBL] [Abstract][Full Text] [Related]  

  • 18. WDR5 modulates cell motility and morphology and controls nuclear changes induced by a 3D environment.
    Wang P; Dreger M; Madrazo E; Williams CJ; Samaniego R; Hodson NW; Monroy F; Baena E; Sánchez-Mateos P; Hurlstone A; Redondo-Muñoz J
    Proc Natl Acad Sci U S A; 2018 Aug; 115(34):8581-8586. PubMed ID: 29987046
    [TBL] [Abstract][Full Text] [Related]  

  • 19. H3K4me2 and WDR5 enriched chromatin interacting long non-coding RNAs maintain transcriptionally competent chromatin at divergent transcriptional units.
    Subhash S; Mishra K; Akhade VS; Kanduri M; Mondal T; Kanduri C
    Nucleic Acids Res; 2018 Oct; 46(18):9384-9400. PubMed ID: 30010961
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
    Zhang P; Chaturvedi CP; Tremblay V; Cramet M; Brunzelle JS; Skiniotis G; Brand M; Shilatifard A; Couture JF
    Genes Dev; 2015 Jan; 29(2):123-8. PubMed ID: 25593305
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.