BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 29930721)

  • 1. The HER2 inhibitor lapatinib potentiates doxorubicin-induced cardiotoxicity through iNOS signaling.
    Hsu WT; Huang CY; Yen CYT; Cheng AL; Hsieh PCH
    Theranostics; 2018; 8(12):3176-3188. PubMed ID: 29930721
    [No Abstract]   [Full Text] [Related]  

  • 2. Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway.
    Sun L; Wang H; Xu D; Yu S; Zhang L; Li X
    Bioengineered; 2022 Jan; 13(1):48-60. PubMed ID: 34898356
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intravenous administration of cardiac progenitor cell-derived exosomes protects against doxorubicin/trastuzumab-induced cardiac toxicity.
    Milano G; Biemmi V; Lazzarini E; Balbi C; Ciullo A; Bolis S; Ameri P; Di Silvestre D; Mauri P; Barile L; Vassalli G
    Cardiovasc Res; 2020 Feb; 116(2):383-392. PubMed ID: 31098627
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protection against Doxorubicin-Induced Cardiotoxicity through Modulating iNOS/ARG 2 Balance by Electroacupuncture at PC6.
    Wang J; Yao L; Wu X; Guo Q; Sun S; Li J; Shi G; Caldwell RB; Caldwell RW; Chen Y
    Oxid Med Cell Longev; 2021; 2021():6628957. PubMed ID: 33824696
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Trastuzumab potentiates doxorubicin-induced cardiotoxicity via activating the NLRP3 inflammasome in vivo and in vitro.
    Wei S; Ma W; Yang Y; Sun T; Jiang C; Liu J; Zhang B; Li W
    Biochem Pharmacol; 2023 Aug; 214():115662. PubMed ID: 37331637
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lapatinib combined with doxorubicin causes dose-dependent cardiotoxicity partially through activating the p38MAPK signaling pathway in zebrafish embryos.
    Du K; Liu Y; Zhang L; Peng L; Dong W; Jiang Y; Niu M; Sun Y; Wu C; Niu Y; Ding Y
    Biomed Pharmacother; 2024 Jun; 175():116637. PubMed ID: 38653111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.
    Cui N; Wu F; Lu WJ; Bai R; Ke B; Liu T; Li L; Lan F; Cui M
    J Cell Mol Med; 2019 Jul; 23(7):4627-4639. PubMed ID: 31106979
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lapatinib inhibits doxorubicin induced migration of HER2-positive breast cancer cells.
    Chintalaramulu N; Vadivelu R; Nguyen NT; Cock IE
    Inflammopharmacology; 2020 Oct; 28(5):1375-1386. PubMed ID: 32378049
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells.
    Nemade H; Chaudhari U; Acharya A; Hescheler J; Hengstler JG; Papadopoulos S; Sachinidis A
    Arch Toxicol; 2018 Apr; 92(4):1507-1524. PubMed ID: 29397400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytes.
    Karhu ST; Kinnunen SM; Tölli M; Välimäki MJ; Szabó Z; Talman V; Ruskoaho H
    Arch Toxicol; 2020 Jun; 94(6):2113-2130. PubMed ID: 32185414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The prostaglandin agonist beraprost aggravates doxorubicin-mediated apoptosis by increasing iNOS expression in cardiomyocytes.
    Lian WS; Chiou HC; Lin H; Chen JJ; Cheng CF
    Curr Vasc Pharmacol; 2015; 13(1):54-63. PubMed ID: 23628005
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Angiotensin-converting enzyme inhibition and angiotensin AT(1)-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity.
    Ibrahim MA; Ashour OM; Ibrahim YF; El-Bitar HI; Gomaa W; Abdel-Rahim SR
    Pharmacol Res; 2009 Nov; 60(5):373-81. PubMed ID: 19467331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective protection of human cardiomyocytes from anthracycline cardiotoxicity by small molecule inhibitors of MAP4K4.
    Golforoush PA; Narasimhan P; Chaves-Guerrero PP; Lawrence E; Newton G; Yan R; Harding SE; Perrior T; Chapman KL; Schneider MD
    Sci Rep; 2020 Jul; 10(1):12060. PubMed ID: 32694738
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An update of the molecular mechanisms underlying doxorubicin plus trastuzumab induced cardiotoxicity.
    Anjos M; Fontes-Oliveira M; Costa VM; Santos M; Ferreira R
    Life Sci; 2021 Sep; 280():119760. PubMed ID: 34166713
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.
    Li M; Sala V; De Santis MC; Cimino J; Cappello P; Pianca N; Di Bona A; Margaria JP; Martini M; Lazzarini E; Pirozzi F; Rossi L; Franco I; Bornbaum J; Heger J; Rohrbach S; Perino A; Tocchetti CG; Lima BHF; Teixeira MM; Porporato PE; Schulz R; Angelini A; Sandri M; Ameri P; Sciarretta S; Lima-Júnior RCP; Mongillo M; Zaglia T; Morello F; Novelli F; Hirsch E; Ghigo A
    Circulation; 2018 Aug; 138(7):696-711. PubMed ID: 29348263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Radiation- and anthracycline-induced cardiac toxicity and the influence of ErbB2 blocking agents.
    Seemann I; te Poele JA; Song JY; Hoving S; Russell NS; Stewart FA
    Breast Cancer Res Treat; 2013 Oct; 141(3):385-95. PubMed ID: 24091769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity.
    Reynolds JG; Geretti E; Hendriks BS; Lee H; Leonard SC; Klinz SG; Noble CO; Lücker PB; Zandstra PW; Drummond DC; Olivier KJ; Nielsen UB; Niyikiza C; Agresta SV; Wickham TJ
    Toxicol Appl Pharmacol; 2012 Jul; 262(1):1-10. PubMed ID: 22676972
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes.
    Cunha-Oliveira T; Ferreira LL; Coelho AR; Deus CM; Oliveira PJ
    Toxicol Appl Pharmacol; 2018 Jun; 348():1-13. PubMed ID: 29653124
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients.
    Haupt LP; Rebs S; Maurer W; Hübscher D; Tiburcy M; Pabel S; Maus A; Köhne S; Tappu R; Haas J; Li Y; Sasse A; Santos CCX; Dressel R; Wojnowski L; Bunt G; Möbius W; Shah AM; Meder B; Wollnik B; Sossalla S; Hasenfuss G; Streckfuss-Bömeke K
    Basic Res Cardiol; 2022 Mar; 117(1):13. PubMed ID: 35260914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes.
    Maillet A; Tan K; Chai X; Sadananda SN; Mehta A; Ooi J; Hayden MR; Pouladi MA; Ghosh S; Shim W; Brunham LR
    Sci Rep; 2016 May; 6():25333. PubMed ID: 27142468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.