393 related articles for article (PubMed ID: 29932898)
1. UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.
Zhou W; Xu J; Tan M; Li H; Li H; Wei W; Sun Y
Mol Cell; 2018 Jun; 70(6):1008-1024.e6. PubMed ID: 29932898
[TBL] [Abstract][Full Text] [Related]
2. Neddylation-CRLs regulate the functions of Treg immune cells.
Wu D; Sun Y
Bioessays; 2023 Apr; 45(4):e2200222. PubMed ID: 36709423
[TBL] [Abstract][Full Text] [Related]
3. Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage.
Zhou W; Xu J; Li H; Xu M; Chen ZJ; Wei W; Pan Z; Sun Y
Clin Cancer Res; 2017 Feb; 23(4):1104-1116. PubMed ID: 27591266
[No Abstract] [Full Text] [Related]
4. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification.
Xu B; Deng Y; Bi R; Guo H; Shu C; Shah NK; Chang J; Liu G; Du Y; Wei W; Wang C
Cancer Chemother Pharmacol; 2018 Jun; 81(6):1083-1093. PubMed ID: 29667067
[TBL] [Abstract][Full Text] [Related]
5. A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer.
Xu T; Ma Q; Li Y; Yu Q; Pan P; Zheng Y; Li Z; Xiong X; Hou T; Yu B; Liu H; Sun Y
Signal Transduct Target Ther; 2022 Oct; 7(1):354. PubMed ID: 36253371
[TBL] [Abstract][Full Text] [Related]
6. Targeting DCN1-UBC12 Protein-Protein Interaction for Regulation of Neddylation Pathway.
Zhou H; Lu J; Yang CY; Sun Y; Wang S
Adv Exp Med Biol; 2020; 1217():349-362. PubMed ID: 31898237
[TBL] [Abstract][Full Text] [Related]
7. Adenovirus oncoprotein E4orf6 triggers Cullin5 neddylation to activate the CLR5 E3 ligase for p53 degradation.
Guo H; Shen S; Li Y; Bi R; Zhang N; Zheng W; Deng Y; Yang Y; Yu XF; Wang C; Wei W
Biochem Biophys Res Commun; 2019 Sep; 516(4):1242-1247. PubMed ID: 31301771
[TBL] [Abstract][Full Text] [Related]
8. The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness.
Wu D; Li H; Liu M; Qin J; Sun Y
Nat Commun; 2022 May; 13(1):3021. PubMed ID: 35641500
[TBL] [Abstract][Full Text] [Related]
9. Targeting neddylation E2s: a novel therapeutic strategy in cancer.
Zheng YC; Guo YJ; Wang B; Wang C; Mamun MAA; Gao Y; Liu HM
J Hematol Oncol; 2021 Apr; 14(1):57. PubMed ID: 33827629
[TBL] [Abstract][Full Text] [Related]
10. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy.
Zhao Y; Morgan MA; Sun Y
Antioxid Redox Signal; 2014 Dec; 21(17):2383-400. PubMed ID: 24410571
[TBL] [Abstract][Full Text] [Related]
11. Induction of NEDD8-conjugating enzyme E2 UBE2F by platinum protects lung cancer cells from apoptosis and confers to platinum-insensitivity.
Zhou L; Zhu J; Chen W; Jiang Y; Hu T; Wang Y; Ye X; Zhan M; Ji C; Xu Z; Wang X; Gu Y; Jia L
Cell Death Dis; 2020 Nov; 11(11):975. PubMed ID: 33184273
[TBL] [Abstract][Full Text] [Related]
12. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
[TBL] [Abstract][Full Text] [Related]
13. The UBE2F-CRL5
Chang Y; Chen Q; Li H; Xu J; Tan M; Xiong X; Sun Y
Dev Cell; 2024 May; 59(10):1317-1332.e5. PubMed ID: 38574733
[TBL] [Abstract][Full Text] [Related]
14. E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.
Huang DT; Ayrault O; Hunt HW; Taherbhoy AM; Duda DM; Scott DC; Borg LA; Neale G; Murray PJ; Roussel MF; Schulman BA
Mol Cell; 2009 Feb; 33(4):483-95. PubMed ID: 19250909
[TBL] [Abstract][Full Text] [Related]
15. Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer.
Soucy TA; Smith PG; Rolfe M
Clin Cancer Res; 2009 Jun; 15(12):3912-6. PubMed ID: 19509147
[TBL] [Abstract][Full Text] [Related]
16. NEDD8-conjugating enzyme E2s: critical targets for cancer therapy.
Zhou L; Lin X; Zhu J; Zhang L; Chen S; Yang H; Jia L; Chen B
Cell Death Discov; 2023 Jan; 9(1):23. PubMed ID: 36690633
[TBL] [Abstract][Full Text] [Related]
17. Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer.
Li L; Kang J; Zhang W; Cai L; Wang S; Liang Y; Jiang Y; Liu X; Zhang Y; Ruan H; Chen G; Wang M; Jia L
EBioMedicine; 2019 Jul; 45():81-91. PubMed ID: 31208947
[TBL] [Abstract][Full Text] [Related]
18. Cullin RING Ligase 5 (CRL-5): Neddylation Activation and Biological Functions.
Zhang S; Sun Y
Adv Exp Med Biol; 2020; 1217():261-283. PubMed ID: 31898233
[TBL] [Abstract][Full Text] [Related]
19. Overactivated neddylation pathway as a therapeutic target in lung cancer.
Li L; Wang M; Yu G; Chen P; Li H; Wei D; Zhu J; Xie L; Jia H; Shi J; Li C; Yao W; Wang Y; Gao Q; Jeong LS; Lee HW; Yu J; Hu F; Mei J; Wang P; Chu Y; Qi H; Yang M; Dong Z; Sun Y; Hoffman RM; Jia L
J Natl Cancer Inst; 2014 Jun; 106(6):dju083. PubMed ID: 24853380
[TBL] [Abstract][Full Text] [Related]
20. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
Luo Z; Pan Y; Jeong LS; Liu J; Jia L
Autophagy; 2012 Nov; 8(11):1677-9. PubMed ID: 22874562
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
