604 related articles for article (PubMed ID: 29936118)
1. Neutralization of negative charges of siRNA results in improved safety and efficient gene silencing activity of lipid nanoparticles loaded with high levels of siRNA.
Sato Y; Matsui H; Sato R; Harashima H
J Control Release; 2018 Aug; 284():179-187. PubMed ID: 29936118
[TBL] [Abstract][Full Text] [Related]
2. Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo.
Sato Y; Hashiba K; Sasaki K; Maeki M; Tokeshi M; Harashima H
J Control Release; 2019 Feb; 295():140-152. PubMed ID: 30610950
[TBL] [Abstract][Full Text] [Related]
3. Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles.
Sato Y; Okabe N; Note Y; Hashiba K; Maeki M; Tokeshi M; Harashima H
Acta Biomater; 2020 Jan; 102():341-350. PubMed ID: 31733331
[TBL] [Abstract][Full Text] [Related]
4. pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes.
Hashiba K; Sato Y; Harashima H
J Control Release; 2017 Sep; 262():239-246. PubMed ID: 28774839
[TBL] [Abstract][Full Text] [Related]
5. Elucidation of the physicochemical properties and potency of siRNA-loaded small-sized lipid nanoparticles for siRNA delivery.
Sato Y; Note Y; Maeki M; Kaji N; Baba Y; Tokeshi M; Harashima H
J Control Release; 2016 May; 229():48-57. PubMed ID: 26995758
[TBL] [Abstract][Full Text] [Related]
6. Effect of the nanoformulation of siRNA-lipid assemblies on their cellular uptake and immune stimulation.
Kubota K; Onishi K; Sawaki K; Li T; Mitsuoka K; Sato T; Takeoka S
Int J Nanomedicine; 2017; 12():5121-5133. PubMed ID: 28790820
[TBL] [Abstract][Full Text] [Related]
7. Reducing the Cytotoxicity of Lipid Nanoparticles Associated with a Fusogenic Cationic Lipid in a Natural Killer Cell Line by Introducing a Polycation-Based siRNA Core.
Nakamura T; Yamada K; Fujiwara Y; Sato Y; Harashima H
Mol Pharm; 2018 Jun; 15(6):2142-2150. PubMed ID: 29668291
[TBL] [Abstract][Full Text] [Related]
8. Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid.
Suzuki Y; Ishihara H
Int J Pharm; 2016 Aug; 510(1):350-8. PubMed ID: 27374199
[TBL] [Abstract][Full Text] [Related]
9. Enhanced Delivery of siRNA to Retinal Ganglion Cells by Intravitreal Lipid Nanoparticles of Positive Charge.
Huang X; Chau Y
Mol Pharm; 2021 Jan; 18(1):377-385. PubMed ID: 33295773
[TBL] [Abstract][Full Text] [Related]
10. Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA.
Ball RL; Hajj KA; Vizelman J; Bajaj P; Whitehead KA
Nano Lett; 2018 Jun; 18(6):3814-3822. PubMed ID: 29694050
[TBL] [Abstract][Full Text] [Related]
11. The development of an in vitro assay to screen lipid based nanoparticles for siRNA delivery.
Zhang Y; Arrington L; Boardman D; Davis J; Xu Y; DiFelice K; Stirdivant S; Wang W; Budzik B; Bawiec J; Deng J; Beutner G; Seifried D; Stanton M; Gindy M; Leone A
J Control Release; 2014 Jan; 174():7-14. PubMed ID: 24240015
[TBL] [Abstract][Full Text] [Related]
12. A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo.
Sato Y; Hatakeyama H; Sakurai Y; Hyodo M; Akita H; Harashima H
J Control Release; 2012 Nov; 163(3):267-76. PubMed ID: 23000694
[TBL] [Abstract][Full Text] [Related]
13. Investigating impacts of surface charge on intraocular distribution of intravitreal lipid nanoparticles.
Huang X; Chau Y
Exp Eye Res; 2019 Sep; 186():107711. PubMed ID: 31238078
[TBL] [Abstract][Full Text] [Related]
14. Size-dependent specific targeting and efficient gene silencing in peritoneal macrophages using a pH-sensitive cationic liposomal siRNA carrier.
Matsui H; Sato Y; Hatakeyama H; Akita H; Harashima H
Int J Pharm; 2015 Nov; 495(1):171-178. PubMed ID: 26355712
[TBL] [Abstract][Full Text] [Related]
15. Quantitation of physiological and biochemical barriers to siRNA liver delivery via lipid nanoparticle platform.
Xu Y; Ou M; Keough E; Roberts J; Koeplinger K; Lyman M; Fauty S; Carlini E; Stern M; Zhang R; Yeh S; Mahan E; Wang Y; Slaughter D; Gindy M; Raab C; Thompson C; Hochman J
Mol Pharm; 2014 May; 11(5):1424-34. PubMed ID: 24588618
[TBL] [Abstract][Full Text] [Related]
16. Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration.
Thanki K; van Eetvelde D; Geyer A; Fraire J; Hendrix R; Van Eygen H; Putteman E; Sami H; de Souza Carvalho-Wodarz C; Franzyk H; Nielsen HM; Braeckmans K; Lehr CM; Ogris M; Foged C
J Control Release; 2019 Sep; 310():82-93. PubMed ID: 31398360
[TBL] [Abstract][Full Text] [Related]
17. Lipid nanoparticles for hepatic delivery of small interfering RNA.
Yu B; Hsu SH; Zhou C; Wang X; Terp MC; Wu Y; Teng L; Mao Y; Wang F; Xue W; Jacob ST; Ghoshal K; Lee RJ; Lee LJ
Biomaterials; 2012 Sep; 33(25):5924-34. PubMed ID: 22652024
[TBL] [Abstract][Full Text] [Related]
18. Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges.
Gomes-da-Silva LC; Fonseca NA; Moura V; Pedroso de Lima MC; Simões S; Moreira JN
Acc Chem Res; 2012 Jul; 45(7):1163-71. PubMed ID: 22568781
[TBL] [Abstract][Full Text] [Related]
19. Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.
Basha G; Novobrantseva TI; Rosin N; Tam YY; Hafez IM; Wong MK; Sugo T; Ruda VM; Qin J; Klebanov B; Ciufolini M; Akinc A; Tam YK; Hope MJ; Cullis PR
Mol Ther; 2011 Dec; 19(12):2186-200. PubMed ID: 21971424
[TBL] [Abstract][Full Text] [Related]
20. Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes.
Bao Y; Jin Y; Chivukula P; Zhang J; Liu Y; Liu J; Clamme JP; Mahato RI; Ng D; Ying W; Wang Y; Yu L
Pharm Res; 2013 Feb; 30(2):342-51. PubMed ID: 22983644
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]