BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 29939445)

  • 1. The JAK1/JAK2- inhibitor ruxolitinib inhibits mast cell degranulation and cytokine release.
    Hermans MAW; Schrijver B; van Holten-Neelen CCPA; Gerth van Wijk R; van Hagen PM; van Daele PLA; Dik WA
    Clin Exp Allergy; 2018 Nov; 48(11):1412-1420. PubMed ID: 29939445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms.
    Parampalli Yajnanarayana S; Stübig T; Cornez I; Alchalby H; Schönberg K; Rudolph J; Triviai I; Wolschke C; Heine A; Brossart P; Kröger N; Wolf D
    Br J Haematol; 2015 Jun; 169(6):824-33. PubMed ID: 25824483
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Xinqin exhibits the anti-allergic effect through the JAK2/STAT5 signaling pathway.
    Zhang Q; Xiong Y; Li GB; Tang Q; Cao M; Huang JB; Xing M; Hu CP; Gong Y; Wang QH; Gao N; Zhang R
    J Ethnopharmacol; 2016 Dec; 193():466-473. PubMed ID: 27666014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of JAK1/2 inhibition on bone marrow stromal cells of myeloproliferative neoplasm (MPN) patients and healthy individuals.
    Zacharaki D; Ghazanfari R; Li H; Lim HC; Scheding S
    Eur J Haematol; 2018 Jul; 101(1):57-67. PubMed ID: 29645296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent repression of C-reactive protein (CRP) expression by the JAK1/2 inhibitor ruxolitinib in inflammatory human hepatocytes.
    Febvre-James M; Lecureur V; Fardel O
    Inflamm Res; 2020 Jan; 69(1):51-62. PubMed ID: 31654094
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human Mast Cell Line HMC1 Expresses Functional Mas-Related G-Protein Coupled Receptor 2.
    Hermans MAW; van Stigt AC; van de Meerendonk S; Schrijver B; van Daele PLA; van Hagen PM; van Splunter M; Dik WA
    Front Immunol; 2021; 12():625284. PubMed ID: 33790895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ruxolitinib, an oral JAK1 and JAK2 inhibitor, in myelofibrosis.
    Vaddi K; Sarlis NJ; Gupta V
    Expert Opin Pharmacother; 2012 Nov; 13(16):2397-407. PubMed ID: 23051187
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-myeloma effects of ruxolitinib combined with bortezomib and lenalidomide: A rationale for JAK/STAT pathway inhibition in myeloma patients.
    de Oliveira MB; Fook-Alves VL; Eugenio AIP; Fernando RC; Sanson LFG; de Carvalho MF; Braga WMT; Davies FE; Colleoni GWB
    Cancer Lett; 2017 Sep; 403():206-215. PubMed ID: 28645562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes.
    Febvre-James M; Bruyère A; Le Vée M; Fardel O
    Drug Metab Dispos; 2018 Feb; 46(2):131-140. PubMed ID: 29162613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia.
    Maude SL; Tasian SK; Vincent T; Hall JW; Sheen C; Roberts KG; Seif AE; Barrett DM; Chen IM; Collins JR; Mullighan CG; Hunger SP; Harvey RC; Willman CL; Fridman JS; Loh ML; Grupp SA; Teachey DT
    Blood; 2012 Oct; 120(17):3510-8. PubMed ID: 22955920
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Repression of interferon β-regulated cytokines by the JAK1/2 inhibitor ruxolitinib in inflammatory human macrophages.
    Febvre-James M; Lecureur V; Augagneur Y; Mayati A; Fardel O
    Int Immunopharmacol; 2018 Jan; 54():354-365. PubMed ID: 29202299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. JAK1/2 and Pan-deacetylase inhibitor combination therapy yields improved efficacy in preclinical mouse models of JAK2V617F-driven disease.
    Evrot E; Ebel N; Romanet V; Roelli C; Andraos R; Qian Z; Dölemeyer A; Dammassa E; Sterker D; Cozens R; Hofmann F; Murakami M; Baffert F; Radimerski T
    Clin Cancer Res; 2013 Nov; 19(22):6230-41. PubMed ID: 24081976
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells.
    Mazzacurati L; Lambert QT; Pradhan A; Griner LN; Huszar D; Reuther GW
    Oncotarget; 2015 Nov; 6(37):40141-57. PubMed ID: 26472029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. JAK1/2 inhibition impairs the development and function of inflammatory dendritic epidermal cells in atopic dermatitis.
    Klaeschen AS; Nümm TJ; Herrmann N; Leib N; Maintz L; Sakai T; Wenzel J; Bieber T
    J Allergy Clin Immunol; 2021 Jun; 147(6):2202-2212.e8. PubMed ID: 33338537
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human Dendritic Cells Mitigate NK-Cell Dysfunction Mediated by Nonselective JAK1/2 Blockade.
    Curran SA; Shyer JA; St Angelo ET; Talbot LR; Sharma S; Chung DJ; Heller G; Hsu KC; Betts BC; Young JW
    Cancer Immunol Res; 2017 Jan; 5(1):52-60. PubMed ID: 27923824
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma.
    Keller A; Wingelhofer B; Peter B; Bauer K; Berger D; Gamperl S; Reifinger M; Cerny-Reiterer S; Moriggl R; Willmann M; Valent P; Hadzijusufovic E
    Vet Comp Oncol; 2018 Mar; 16(1):55-68. PubMed ID: 28397975
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined anti-fibrotic and anti-inflammatory properties of JAK-inhibitors on macrophages in vitro and in vivo: Perspectives for scleroderma-associated interstitial lung disease.
    Lescoat A; Lelong M; Jeljeli M; Piquet-Pellorce C; Morzadec C; Ballerie A; Jouneau S; Jego P; Vernhet L; Batteux F; Fardel O; Lecureur V
    Biochem Pharmacol; 2020 Aug; 178():114103. PubMed ID: 32562787
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Remission of food allergy by the Janus kinase inhibitor ruxolitinib in mice.
    Yamaki K; Yoshino S
    Int Immunopharmacol; 2014 Feb; 18(2):217-24. PubMed ID: 24332884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19.
    Goker Bagca B; Biray Avci C
    Cytokine Growth Factor Rev; 2020 Aug; 54():51-62. PubMed ID: 32636055
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IL-6 stimulation of DNA replication is JAK1/2 mediated in cross-talk with hyperactivated ERK1/2 signaling.
    Subotički T; Mitrović Ajtić O; Beleslin-Čokić BB; Bjelica S; Djikić D; Diklić M; Leković D; Gotić M; Santibanez JF; Noguchi CT; Čokić VP
    Cell Biol Int; 2019 Feb; 43(2):192-206. PubMed ID: 30571852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.