243 related articles for article (PubMed ID: 29940336)
1. α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy.
Wong SQ; Pontifex MG; Phelan MM; Pidathala C; Kraemer BC; Barclay JW; Berry NG; O'Neill PM; Burgoyne RD; Morgan A
Neurobiol Dis; 2018 Oct; 118():40-54. PubMed ID: 29940336
[TBL] [Abstract][Full Text] [Related]
2. Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression.
Chen X; McCue HV; Wong SQ; Kashyap SS; Kraemer BC; Barclay JW; Burgoyne RD; Morgan A
Mol Neurodegener; 2015 Sep; 10():51. PubMed ID: 26419537
[TBL] [Abstract][Full Text] [Related]
3. CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Liachko NF; McMillan PJ; Guthrie CR; Bird TD; Leverenz JB; Kraemer BC
Ann Neurol; 2013 Jul; 74(1):39-52. PubMed ID: 23424178
[TBL] [Abstract][Full Text] [Related]
4. Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.
Liachko NF; Saxton AD; McMillan PJ; Strovas TJ; Keene CD; Bird TD; Kraemer BC
PLoS Genet; 2019 Dec; 15(12):e1008526. PubMed ID: 31834878
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy.
Liachko NF; Guthrie CR; Kraemer BC
J Neurosci; 2010 Dec; 30(48):16208-19. PubMed ID: 21123567
[TBL] [Abstract][Full Text] [Related]
6. Caenorhabditis elegans RNA-processing protein TDP-1 regulates protein homeostasis and life span.
Zhang T; Hwang HY; Hao H; Talbot C; Wang J
J Biol Chem; 2012 Mar; 287(11):8371-82. PubMed ID: 22232551
[TBL] [Abstract][Full Text] [Related]
7. Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS).
Aaron C; Beaudry G; Parker JA; Therrien M
J Agric Food Chem; 2016 May; 64(17):3338-44. PubMed ID: 27071850
[TBL] [Abstract][Full Text] [Related]
8. TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling.
Zhang T; Mullane PC; Periz G; Wang J
Hum Mol Genet; 2011 May; 20(10):1952-65. PubMed ID: 21355045
[TBL] [Abstract][Full Text] [Related]
9. TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans.
Shen L; Wang C; Chen L; Leung KL; Lo E; Lakso M; Wong G
Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165876. PubMed ID: 32531261
[TBL] [Abstract][Full Text] [Related]
10. Alpha-linolenic acid suppresses dopaminergic neurodegeneration induced by 6-OHDA in C. elegans.
Shashikumar S; Pradeep H; Chinnu S; Rajini PS; Rajanikant GK
Physiol Behav; 2015 Nov; 151():563-9. PubMed ID: 26300470
[TBL] [Abstract][Full Text] [Related]
11. TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.
Aggad D; Vérièpe J; Tauffenberger A; Parker JA
J Neurosci; 2014 Sep; 34(36):12093-103. PubMed ID: 25186754
[TBL] [Abstract][Full Text] [Related]
12. TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans.
Vaccaro A; Tauffenberger A; Ash PE; Carlomagno Y; Petrucelli L; Parker JA
PLoS Genet; 2012 Jul; 8(7):e1002806. PubMed ID: 22792076
[TBL] [Abstract][Full Text] [Related]
13. A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action.
Wong SQ; Jones A; Dodd S; Grimes D; Barclay JW; Marson AG; Cunliffe VT; Burgoyne RD; Sills GJ; Morgan A
J Neurosci Methods; 2018 Nov; 309():132-142. PubMed ID: 30189284
[TBL] [Abstract][Full Text] [Related]
14. Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice.
Medina DX; Orr ME; Oddo S
Neurobiol Aging; 2014 Jan; 35(1):79-87. PubMed ID: 23954172
[TBL] [Abstract][Full Text] [Related]
15. Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.
Kumar S; Phaneuf D; Cordeau P; Boutej H; Kriz J; Julien JP
Mol Neurodegener; 2021 Jan; 16(1):1. PubMed ID: 33413517
[TBL] [Abstract][Full Text] [Related]
16. Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration.
Zhan L; Xie Q; Tibbetts RS
Hum Mol Genet; 2015 Feb; 24(3):757-72. PubMed ID: 25281658
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.
Vaccaro A; Patten SA; Aggad D; Julien C; Maios C; Kabashi E; Drapeau P; Parker JA
Neurobiol Dis; 2013 Jul; 55():64-75. PubMed ID: 23567652
[TBL] [Abstract][Full Text] [Related]
18. Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.
Tardiff DF; Tucci ML; Caldwell KA; Caldwell GA; Lindquist S
J Biol Chem; 2012 Feb; 287(6):4107-20. PubMed ID: 22147697
[TBL] [Abstract][Full Text] [Related]
19. TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Wang P; Deng J; Dong J; Liu J; Bigio EH; Mesulam M; Wang T; Sun L; Wang L; Lee AY; McGee WA; Chen X; Fushimi K; Zhu L; Wu JY
PLoS Genet; 2019 May; 15(5):e1007947. PubMed ID: 31100073
[TBL] [Abstract][Full Text] [Related]
20. Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.
Vaccaro A; Tauffenberger A; Aggad D; Rouleau G; Drapeau P; Parker JA
PLoS One; 2012; 7(2):e31321. PubMed ID: 22363618
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
