BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 29941447)

  • 1. Nonsynonymous Variants in
    Kwak SH; Chae J; Lee S; Choi S; Koo BK; Yoon JW; Park JH; Cho B; Moon MK; Lim S; Cho YM; Moon S; Kim YJ; Han S; Hwang MY; Cho YS; Lee MS; Jang HC; Kang HM; Park T; Cho NH; Kim K; Kim JI; Park KS
    Diabetes; 2018 Sep; 67(9):1892-1902. PubMed ID: 29941447
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exome-chip association analysis reveals an Asian-specific missense variant in PAX4 associated with type 2 diabetes in Chinese individuals.
    Cheung CY; Tang CS; Xu A; Lee CH; Au KW; Xu L; Fong CH; Kwok KH; Chow WS; Woo YC; Yuen MM; Hai JS; Jin YL; Cheung BM; Tan KC; Cherny SS; Zhu F; Zhu T; Thomas GN; Cheng KK; Jiang CQ; Lam TH; Tse HF; Sham PC; Lam KS
    Diabetologia; 2017 Jan; 60(1):107-115. PubMed ID: 27744525
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PAX4 R192H and P321H polymorphisms in type 2 diabetes and their functional defects.
    Sujjitjoon J; Kooptiwut S; Chongjaroen N; Semprasert N; Hanchang W; Chanprasert K; Tangjittipokin W; Yenchitsomanus PT; Plengvidhya N
    J Hum Genet; 2016 Nov; 61(11):943-949. PubMed ID: 27334367
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell.
    Kulzer JR; Stitzel ML; Morken MA; Huyghe JR; Fuchsberger C; Kuusisto J; Laakso M; Boehnke M; Collins FS; Mohlke KL
    Am J Hum Genet; 2014 Feb; 94(2):186-97. PubMed ID: 24439111
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PAX4 R192H is associated with younger onset of Type 2 diabetes in East Asians in Singapore.
    Ang SF; Tan CSH; Wang L; Dorajoo R; Fong JCW; Kon WYC; Lian JX; Ang K; Rahim JB; Jeevith B; Lee SBM; Tang WE; Subramanium T; Sum CF; Liu JJ; Lim SC
    J Diabetes Complications; 2019 Jan; 33(1):53-58. PubMed ID: 30528630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.
    Ma RC; Hu C; Tam CH; Zhang R; Kwan P; Leung TF; Thomas GN; Go MJ; Hara K; Sim X; Ho JS; Wang C; Li H; Lu L; Wang Y; Li JW; Wang Y; Lam VK; Wang J; Yu W; Kim YJ; Ng DP; Fujita H; Panoutsopoulou K; Day-Williams AG; Lee HM; Ng AC; Fang YJ; Kong AP; Jiang F; Ma X; Hou X; Tang S; Lu J; Yamauchi T; Tsui SK; Woo J; Leung PC; Zhang X; Tang NL; Sy HY; Liu J; Wong TY; Lee JY; Maeda S; Xu G; Cherny SS; Chan TF; Ng MC; Xiang K; Morris AP; ; Keildson S; ; Hu R; Ji L; Lin X; Cho YS; Kadowaki T; Tai ES; Zeggini E; McCarthy MI; Hon KL; Baum L; Tomlinson B; So WY; Bao Y; Chan JC; Jia W
    Diabetologia; 2013 Jun; 56(6):1291-305. PubMed ID: 23532257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development.
    Lau HH; Krentz NAJ; Abaitua F; Perez-Alcantara M; Chan JW; Ajeian J; Ghosh S; Lee Y; Yang J; Thaman S; Champon B; Sun H; Jha A; Hoon S; Tan NS; Gardner DS; Kao SL; Tai ES; Gloyn AL; Teo AKK
    Nat Commun; 2023 Sep; 14(1):6119. PubMed ID: 37777536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
    Wessel J; Chu AY; Willems SM; Wang S; Yaghootkar H; Brody JA; Dauriz M; Hivert MF; Raghavan S; Lipovich L; Hidalgo B; Fox K; Huffman JE; An P; Lu Y; Rasmussen-Torvik LJ; Grarup N; Ehm MG; Li L; Baldridge AS; Stančáková A; Abrol R; Besse C; Boland A; Bork-Jensen J; Fornage M; Freitag DF; Garcia ME; Guo X; Hara K; Isaacs A; Jakobsdottir J; Lange LA; Layton JC; Li M; Hua Zhao J; Meidtner K; Morrison AC; Nalls MA; Peters MJ; Sabater-Lleal M; Schurmann C; Silveira A; Smith AV; Southam L; Stoiber MH; Strawbridge RJ; Taylor KD; Varga TV; Allin KH; Amin N; Aponte JL; Aung T; Barbieri C; Bihlmeyer NA; Boehnke M; Bombieri C; Bowden DW; Burns SM; Chen Y; Chen YD; Cheng CY; Correa A; Czajkowski J; Dehghan A; Ehret GB; Eiriksdottir G; Escher SA; Farmaki AE; Frånberg M; Gambaro G; Giulianini F; Goddard WA; Goel A; Gottesman O; Grove ML; Gustafsson S; Hai Y; Hallmans G; Heo J; Hoffmann P; Ikram MK; Jensen RA; Jørgensen ME; Jørgensen T; Karaleftheri M; Khor CC; Kirkpatrick A; Kraja AT; Kuusisto J; Lange EM; Lee IT; Lee WJ; Leong A; Liao J; Liu C; Liu Y; Lindgren CM; Linneberg A; Malerba G; Mamakou V; Marouli E; Maruthur NM; Matchan A; McKean-Cowdin R; McLeod O; Metcalf GA; Mohlke KL; Muzny DM; Ntalla I; Palmer ND; Pasko D; Peter A; Rayner NW; Renström F; Rice K; Sala CF; Sennblad B; Serafetinidis I; Smith JA; Soranzo N; Speliotes EK; Stahl EA; Stirrups K; Tentolouris N; Thanopoulou A; Torres M; Traglia M; Tsafantakis E; Javad S; Yanek LR; Zengini E; Becker DM; Bis JC; Brown JB; Cupples LA; Hansen T; Ingelsson E; Karter AJ; Lorenzo C; Mathias RA; Norris JM; Peloso GM; Sheu WH; Toniolo D; Vaidya D; Varma R; Wagenknecht LE; Boeing H; Bottinger EP; Dedoussis G; Deloukas P; Ferrannini E; Franco OH; Franks PW; Gibbs RA; Gudnason V; Hamsten A; Harris TB; Hattersley AT; Hayward C; Hofman A; Jansson JH; Langenberg C; Launer LJ; Levy D; Oostra BA; O'Donnell CJ; O'Rahilly S; Padmanabhan S; Pankow JS; Polasek O; Province MA; Rich SS; Ridker PM; Rudan I; Schulze MB; Smith BH; Uitterlinden AG; Walker M; Watkins H; Wong TY; Zeggini E; ; Laakso M; Borecki IB; Chasman DI; Pedersen O; Psaty BM; Tai ES; van Duijn CM; Wareham NJ; Waterworth DM; Boerwinkle E; Kao WH; Florez JC; Loos RJ; Wilson JG; Frayling TM; Siscovick DS; Dupuis J; Rotter JI; Meigs JB; Scott RA; Goodarzi MO
    Nat Commun; 2015 Jan; 6():5897. PubMed ID: 25631608
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes.
    Deaton AM; Parker MM; Ward LD; Flynn-Carroll AO; BonDurant L; Hinkle G; Akbari P; Lotta LA; ; ; Baras A; Nioi P
    Sci Rep; 2021 Nov; 11(1):21565. PubMed ID: 34732801
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus.
    Tokuyama Y; Matsui K; Ishizuka T; Egashira T; Kanatsuka A
    Metabolism; 2006 Feb; 55(2):213-6. PubMed ID: 16423628
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PAX4 mutations in Thais with maturity onset diabetes of the young.
    Plengvidhya N; Kooptiwut S; Songtawee N; Doi A; Furuta H; Nishi M; Nanjo K; Tantibhedhyangkul W; Boonyasrisawat W; Yenchitsomanus PT; Doria A; Banchuin N
    J Clin Endocrinol Metab; 2007 Jul; 92(7):2821-6. PubMed ID: 17426099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic risk score combining six genetic variants associated with the cellular NRF2 expression levels correlates with Type 2 diabetes in the human population.
    Shin JH; Lee KM; Shin J; Kang KD; Nho CW; Cho YS
    Genes Genomics; 2019 May; 41(5):537-545. PubMed ID: 30767168
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
    Scott RA; Freitag DF; Li L; Chu AY; Surendran P; Young R; Grarup N; Stancáková A; Chen Y; Varga TV; Yaghootkar H; Luan J; Zhao JH; Willems SM; Wessel J; Wang S; Maruthur N; Michailidou K; Pirie A; van der Lee SJ; Gillson C; Al Olama AA; Amouyel P; Arriola L; Arveiler D; Aviles-Olmos I; Balkau B; Barricarte A; Barroso I; Garcia SB; Bis JC; Blankenberg S; Boehnke M; Boeing H; Boerwinkle E; Borecki IB; Bork-Jensen J; Bowden S; Caldas C; Caslake M; ; Cupples LA; Cruchaga C; Czajkowski J; den Hoed M; Dunn JA; Earl HM; Ehret GB; Ferrannini E; Ferrieres J; Foltynie T; Ford I; Forouhi NG; Gianfagna F; Gonzalez C; Grioni S; Hiller L; Jansson JH; Jørgensen ME; Jukema JW; Kaaks R; Kee F; Kerrison ND; Key TJ; Kontto J; Kote-Jarai Z; Kraja AT; Kuulasmaa K; Kuusisto J; Linneberg A; Liu C; Marenne G; Mohlke KL; Morris AP; Muir K; Müller-Nurasyid M; Munroe PB; Navarro C; Nielsen SF; Nilsson PM; Nordestgaard BG; Packard CJ; Palli D; Panico S; Peloso GM; Perola M; Peters A; Poole CJ; Quirós JR; Rolandsson O; Sacerdote C; Salomaa V; Sánchez MJ; Sattar N; Sharp SJ; Sims R; Slimani N; Smith JA; Thompson DJ; Trompet S; Tumino R; van der A DL; van der Schouw YT; Virtamo J; Walker M; Walter K; ; ; ; ; ; ; ; Abraham JE; Amundadottir LT; Aponte JL; Butterworth AS; Dupuis J; Easton DF; Eeles RA; Erdmann J; Franks PW; Frayling TM; Hansen T; Howson JM; Jørgensen T; Kooner J; Laakso M; Langenberg C; McCarthy MI; Pankow JS; Pedersen O; Riboli E; Rotter JI; Saleheen D; Samani NJ; Schunkert H; Vollenweider P; O'Rahilly S; ; ; ; Deloukas P; Danesh J; Goodarzi MO; Kathiresan S; Meigs JB; Ehm MG; Wareham NJ; Waterworth DM
    Sci Transl Med; 2016 Jun; 8(341):341ra76. PubMed ID: 27252175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes.
    Kooptiwut S; Plengvidhya N; Chukijrungroat T; Sujjitjoon J; Semprasert N; Furuta H; Yenchitsomanus PT
    J Diabetes Complications; 2012; 26(4):343-7. PubMed ID: 22521316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ethnic-Specific Type 2 Diabetes Risk Factor PAX4 R192H Is Associated with Attention-Specific Cognitive Impairment in Chinese with Type 2 Diabetes.
    Ang SF; Low S; Ng TP; Tan CSH; Ang K; Lim Z; Tang WE; Subramaniam T; Sum CF; Lim SC
    J Alzheimers Dis; 2022; 88(1):241-249. PubMed ID: 35570489
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Association between A1168C polymorphism in PAX4 gene and type 1 diabetes in Han Chinese].
    Zhang Y; Xiao XH; Wang H; Wang T; Sun Q; Yang GH; Fu Y; Yuan T; Zhang Q; Liu QY
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2007 Jun; 29(3):370-3. PubMed ID: 17633464
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity.
    Biason-Lauber A; Boehm B; Lang-Muritano M; Gauthier BR; Brun T; Wollheim CB; Schoenle EJ
    Diabetologia; 2005 May; 48(5):900-5. PubMed ID: 15834548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes.
    Melchiorsen JU; Sørensen KV; Bork-Jensen J; Kizilkaya HS; Gasbjerg LS; Hauser AS; Rungby J; Sørensen HT; Vaag A; Nielsen JS; Pedersen O; Linneberg A; Hartmann B; Gjesing AP; Holst JJ; Hansen T; Rosenkilde MM; Grarup N
    J Clin Endocrinol Metab; 2023 Oct; 108(11):2821-2833. PubMed ID: 37235780
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NeuroD1 A45T and PAX4 R121W polymorphisms are associated with plasma glucose level of repaglinide monotherapy in Chinese patients with type 2 diabetes.
    Gong ZC; Huang Q; Dai XP; Lei GH; Lu HB; Yin JY; Xu XJ; Qu J; Pei Q; Dong M; Zhou BT; Shen J; Zhou G; Zhou HH; Liu ZQ
    Br J Clin Pharmacol; 2012 Sep; 74(3):501-9. PubMed ID: 22296034
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
    Cho YS; Chen CH; Hu C; Long J; Ong RT; Sim X; Takeuchi F; Wu Y; Go MJ; Yamauchi T; Chang YC; Kwak SH; Ma RC; Yamamoto K; Adair LS; Aung T; Cai Q; Chang LC; Chen YT; Gao Y; Hu FB; Kim HL; Kim S; Kim YJ; Lee JJ; Lee NR; Li Y; Liu JJ; Lu W; Nakamura J; Nakashima E; Ng DP; Tay WT; Tsai FJ; Wong TY; Yokota M; Zheng W; Zhang R; Wang C; So WY; Ohnaka K; Ikegami H; Hara K; Cho YM; Cho NH; Chang TJ; Bao Y; Hedman ÅK; Morris AP; McCarthy MI; ; ; Takayanagi R; Park KS; Jia W; Chuang LM; Chan JC; Maeda S; Kadowaki T; Lee JY; Wu JY; Teo YY; Tai ES; Shu XO; Mohlke KL; Kato N; Han BG; Seielstad M
    Nat Genet; 2011 Dec; 44(1):67-72. PubMed ID: 22158537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.