These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 29944945)

  • 41. Evaluation of a dual-wavelength size exclusion HPLC method with improved sensitivity to detect protein aggregates and its use to better characterize degradation pathways of an IgG1 monoclonal antibody.
    Bond MD; Panek ME; Zhang Z; Wang D; Mehndiratta P; Zhao H; Gunton K; Ni A; Nedved ML; Burman S; Volkin DB
    J Pharm Sci; 2010 Jun; 99(6):2582-97. PubMed ID: 20039394
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody.
    Arora J; Hickey JM; Majumdar R; Esfandiary R; Bishop SM; Samra HS; Middaugh CR; Weis DD; Volkin DB
    MAbs; 2015; 7(3):525-39. PubMed ID: 25875351
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Improved Comparative Signature Diagrams to Evaluate Similarity of Storage Stability Profiles of Different IgG1 mAbs.
    Kim JH; Joshi SB; Esfandiary R; Iyer V; Bishop SM; Volkin DB; Middaugh CR
    J Pharm Sci; 2016 Mar; 105(3):1028-35. PubMed ID: 26886311
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Distinct aggregation mechanisms of monoclonal antibody under thermal and freeze-thaw stresses revealed by hydrogen exchange.
    Zhang A; Singh SK; Shirts MR; Kumar S; Fernandez EJ
    Pharm Res; 2012 Jan; 29(1):236-50. PubMed ID: 21805212
    [TBL] [Abstract][Full Text] [Related]  

  • 45. The missing piece in the puzzle: Prediction of aggregation via the protein-protein interaction parameter A
    Koepf E; Schroeder R; Brezesinski G; Friess W
    Eur J Pharm Biopharm; 2018 Jul; 128():200-209. PubMed ID: 29723667
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Peptide Dendrons as Thermal-Stability Amplifiers for Immunoglobulin G1 Monoclonal Antibody Biotherapeutics.
    Bansal R; Dhawan S; Chattopadhyay S; Maurya GP; Haridas V; Rathore AS
    Bioconjug Chem; 2017 Oct; 28(10):2549-2559. PubMed ID: 28880521
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synergistic Effect of Cavitation and Agitation on Protein Aggregation.
    Torisu T; Maruno T; Hamaji Y; Ohkubo T; Uchiyama S
    J Pharm Sci; 2017 Feb; 106(2):521-529. PubMed ID: 27887723
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs.
    Clark RH; Latypov RF; De Imus C; Carter J; Wilson Z; Manchulenko K; Brown ME; Ketchem RR
    MAbs; 2014; 6(6):1540-50. PubMed ID: 25484048
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Arginine as an eluent for automated on-line Protein A/size exclusion chromatographic analysis of monoclonal antibody aggregates in cell culture.
    Wang S; Raghani A
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Jan; 945-946():115-20. PubMed ID: 24333642
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Effect of Thermal and Shear Stressors on the Physical Properties, Structural Integrity and Biological Activity of the Anti-TNF-alpha Monoclonal Antibody, Infliximab.
    Alsaddique JA; Pabari RM; Ramtoola Z
    Curr Pharm Biotechnol; 2016; 17(10):905-14. PubMed ID: 27194359
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Aggregation mechanism of an IgG2 and two IgG1 monoclonal antibodies at low pH: from oligomers to larger aggregates.
    Arosio P; Rima S; Morbidelli M
    Pharm Res; 2013 Mar; 30(3):641-54. PubMed ID: 23054090
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Dextrose-mediated aggregation of therapeutic monoclonal antibodies in human plasma: Implication of isoelectric precipitation of complement proteins.
    Luo S; Zhang B
    MAbs; 2015; 7(6):1094-103. PubMed ID: 26338058
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Accelerated Aggregation Studies of Monoclonal Antibodies: Considerations for Storage Stability.
    Wälchli R; Vermeire PJ; Massant J; Arosio P
    J Pharm Sci; 2020 Jan; 109(1):595-602. PubMed ID: 31676272
    [TBL] [Abstract][Full Text] [Related]  

  • 54. An accelerated surface-mediated stress assay of antibody instability for developability studies.
    Kopp MRG; Wolf Pérez AM; Zucca MV; Capasso Palmiero U; Friedrichsen B; Lorenzen N; Arosio P
    MAbs; 2020; 12(1):1815995. PubMed ID: 32954930
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Characterization of the physical stability of a lyophilized IgG1 mAb after accelerated shipping-like stress.
    Telikepalli S; Kumru OS; Kim JH; Joshi SB; O'Berry KB; Blake-Haskins AW; Perkins MD; Middaugh CR; Volkin DB
    J Pharm Sci; 2015 Feb; 104(2):495-507. PubMed ID: 25522000
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Probing Conformational Diversity of Fc Domains in Aggregation-Prone Monoclonal Antibodies.
    Majumder S; Jones MT; Kimmel M; Alphonse Ignatius A
    Pharm Res; 2018 Sep; 35(11):220. PubMed ID: 30255351
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Understanding the freezing of biopharmaceuticals: first-principle modeling of the process and evaluation of its effect on product quality.
    Radmanovic N; Serno T; Joerg S; Germershaus O
    J Pharm Sci; 2013 Aug; 102(8):2495-507. PubMed ID: 23775776
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Accelerated stability studies of abatacept formulations: comparison of freeze-thawing- and agitation-induced stresses.
    Cordes AA; Carpenter JF; Randolph TW
    J Pharm Sci; 2012 Jul; 101(7):2307-15. PubMed ID: 22488299
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Sorbitol crystallization-induced aggregation in frozen mAb formulations.
    Piedmonte DM; Hair A; Baker P; Brych L; Nagapudi K; Lin H; Cao W; Hershenson S; Ratnaswamy G
    J Pharm Sci; 2015 Feb; 104(2):686-97. PubMed ID: 25219372
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Impact of Freeze/Thaw Process on Drug Substance Storage of Therapeutics.
    Rayfield WJ; Kandula S; Khan H; Tugcu N
    J Pharm Sci; 2017 Aug; 106(8):1944-1951. PubMed ID: 28343990
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.